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The map label for this gene is csgD [H]

Identifier: 37681138

GI number: 37681138

Start: 3019881

End: 3020528

Strand: Direct

Name: csgD [H]

Synonym: VV2954

Alternate gene names: 37681138

Gene position: 3019881-3020528 (Clockwise)

Preceding gene: 37681110

Following gene: 37681139

Centisome position: 90.02

GC content: 44.44

Gene sequence:

>648_bases
ATGAGAAAATCTTCTTACGCGCGGAAGCCATTTTTTATCAGTTTGCAAAACGAACAAACTCCTGAGTTCGTCACGGTATT
AGCTAAACAGATTCAAATGGAGATCCCTGTGATTACCCCGGCAACGCTCATGCAAGCCGATCCCAATCATCGTAATCGCA
TCTTATTAATTGATCATCAGCAACATAAGGTGCTGTTGAGAGAAATTAAAAACCTACCCCTGATATGGAAAGGGTTTGAA
ACTGTCCTGTGTAATGTACCTAGCCGATTGACGACTGAGGAACTGATCGGTTTTGGCCAGTGCAAAGCGATCTTCTACCG
AGACACCGCCATTACAGACATGGCCAAAGGACTAAATTCGGTGATTAATGGCAAAAGCTGGCTGCCACGCGACGTCAGCG
CACAACTCATCCACTACTATCGAAATATGGTTTGTTCACACACTTCACCAGTGAATGTGGATCTCACGATGAGAGAAATT
CAAGTGTTACGCTGCGTGCAGTCTGGCAAGTCAAATTCTCAAATCGCCGAAGATCTTTTCATTAGTGAATTCACCGTAAA
GTCGCATCTCTATCAAACCTTTAGAAAGCTCTCCGTGAAGAATCGTGTCCAAGCTGCCGCGTGGGCTGACCAAAATTTGA
TCTCATAA

Upstream 100 bases:

>100_bases
GCATTTCACTATTCTGCCAGTAGCCTGTGCGATTTAATGATGACAACGTTGCACCCGCGCATTCGACTTATTCAATAATT
AACCATAAATGGAGGTTGTT

Downstream 100 bases:

>100_bases
GTAAGAAGATCGCGAATTTTCCTTTAGAGTGTAACGTATGACAAAATAACAGGTTAGAATCGCCCCTAATGATAACTAAC
TGTTTATGGAACGACACACT

Product: DNA-binding HTH domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRKSSYARKPFFISLQNEQTPEFVTVLAKQIQMEIPVITPATLMQADPNHRNRILLIDHQQHKVLLREIKNLPLIWKGFE
TVLCNVPSRLTTEELIGFGQCKAIFYRDTAITDMAKGLNSVINGKSWLPRDVSAQLIHYYRNMVCSHTSPVNVDLTMREI
QVLRCVQSGKSNSQIAEDLFISEFTVKSHLYQTFRKLSVKNRVQAAAWADQNLIS

Sequences:

>Translated_215_residues
MRKSSYARKPFFISLQNEQTPEFVTVLAKQIQMEIPVITPATLMQADPNHRNRILLIDHQQHKVLLREIKNLPLIWKGFE
TVLCNVPSRLTTEELIGFGQCKAIFYRDTAITDMAKGLNSVINGKSWLPRDVSAQLIHYYRNMVCSHTSPVNVDLTMREI
QVLRCVQSGKSNSQIAEDLFISEFTVKSHLYQTFRKLSVKNRVQAAAWADQNLIS
>Mature_215_residues
MRKSSYARKPFFISLQNEQTPEFVTVLAKQIQMEIPVITPATLMQADPNHRNRILLIDHQQHKVLLREIKNLPLIWKGFE
TVLCNVPSRLTTEELIGFGQCKAIFYRDTAITDMAKGLNSVINGKSWLPRDVSAQLIHYYRNMVCSHTSPVNVDLTMREI
QVLRCVQSGKSNSQIAEDLFISEFTVKSHLYQTFRKLSVKNRVQAAAWADQNLIS

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=199, Percent_Identity=29.1457286432161, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 24674; Mature: 24674

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSSYARKPFFISLQNEQTPEFVTVLAKQIQMEIPVITPATLMQADPNHRNRILLIDHQ
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECH
QHKVLLREIKNLPLIWKGFETVLCNVPSRLTTEELIGFGQCKAIFYRDTAITDMAKGLNS
HHHHHHHHHHCCCEEECCHHHHHHCCCCCCCHHHHHCCCCCEEEEEECHHHHHHHHHHHH
VINGKSWLPRDVSAQLIHYYRNMVCSHTSPVNVDLTMREIQVLRCVQSGKSNSQIAEDLF
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHH
ISEFTVKSHLYQTFRKLSVKNRVQAAAWADQNLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKSSYARKPFFISLQNEQTPEFVTVLAKQIQMEIPVITPATLMQADPNHRNRILLIDHQ
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECH
QHKVLLREIKNLPLIWKGFETVLCNVPSRLTTEELIGFGQCKAIFYRDTAITDMAKGLNS
HHHHHHHHHHCCCEEECCHHHHHHCCCCCCCHHHHHCCCCCEEEEEECHHHHHHHHHHHH
VINGKSWLPRDVSAQLIHYYRNMVCSHTSPVNVDLTMREIQVLRCVQSGKSNSQIAEDLF
HHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHH
ISEFTVKSHLYQTFRKLSVKNRVQAAAWADQNLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]