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The map label for this gene is yggW [H]

Identifier: 37681064

GI number: 37681064

Start: 2931675

End: 2932844

Strand: Direct

Name: yggW [H]

Synonym: VV2880

Alternate gene names: 37681064

Gene position: 2931675-2932844 (Clockwise)

Preceding gene: 161486599

Following gene: 37681068

Centisome position: 87.4

GC content: 48.21

Gene sequence:

>1170_bases
ATGTTAACGCCCCCAGCACTCAGTTTGTATGTTCACATCCCATGGTGTGTACAAAAGTGCCCTTATTGCGACTTCAACTC
TCACACACTCAAAGAGCAGATCCCAGAGCAGATGTACATCAATGCGCTGCTGGAAGATCTTGACCGTGATATCGAAAAGT
ATCAGCTTCACCGCGCGCCAAGACCACTGCACTCGATTTTTATCGGTGGAGGCACACCAAGCCTCATCTCAGCAGAAGGC
ATTCGAGATCTTTTGCAAGGGATCGAAAAACGCATTCCCTTTACGCCTTCGATCGAGATCACCATGGAAGCCAATCCCGG
CACCATCGAAGCTGAGCGCTTTGCGGGCTATCGCAAAGCAGGGGTCACGCGCATCTCCATCGGTGTACAAAGTTTTGAGC
AGCAAAAACTTGAGCGTTTGGGGCGTATTCATGGCCAAGATGAAGCAGTGAACGCCGCGAAACTGGCTCATCAAATTGGC
TTGAACAGTTTTAACCTCGATCTCATGCACGGTTTGCCCGATCAAAGCATCGAACAAGCTCTGGCCGATCTGGACAAAGC
GATTGAACTTAATCCGCCTCATCTTTCTTGGTATCAGCTCACTATTGAGCCAAATACCATGTTCTACTACAAACCGCCGG
CTCTCCCCGACGACGACCAGTTGTGGGACATCTTTGAGCGAGGTCATCAAAAACTCACACAAGCGGGATACGTGCAGTAT
GAGATTTCCGGTTACAGCAAACCCGGTTATCAATGTCAGCACAATCTTAACTACTGGCGTTTTGGTGATTACTTAGGGAT
TGGCTGTGGCTCACACGGCAAACTGAGCTTTGCTGACGGTCGCATCATTCGCACCACCAAAATTAAGCACCCGAAGGGCT
ACTTGGCGGCGCATCAAAATATGGTCAAACCCTATCTTGATAGCGAACAGTTGGTCGAAGAGATCGATCGTCCGTTCGAG
TTCTTTATGAATCGCTTTAGATTGATGGAAGCGTGCCCTAAACAAGATTTCATTGATACAACAGGGCTACCACTGAGTTT
TATCGAGACAACCATTCAATGGGCCGTTGAGATGGGCTATTTGAATGACAACGAAACCAGTTGGCAAATCACAGAGAAAG
GTAAGCTGTTCCTAAACGACTTGCTCGAAGCGTTTATGGCTGAAGAGTAA

Upstream 100 bases:

>100_bases
GCTTGAACCTGTGCGCAAGAAACAACTCTCTCATCGTGGTAAAGCATTGAAACAGCTTTTTGCTACGCTACGTGAACAAC
CTTTAGTGTAAGGTACTCGC

Downstream 100 bases:

>100_bases
CCTACTCGGAGAGCAGTTCGGCATCCAGCATCTCCCAGATATGCAAAGCAAGATAGGTACGATAAGGCGTGGCTGCGGAT
AAAATAGCTTCTGCATCAAC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLTPPALSLYVHIPWCVQKCPYCDFNSHTLKEQIPEQMYINALLEDLDRDIEKYQLHRAPRPLHSIFIGGGTPSLISAEG
IRDLLQGIEKRIPFTPSIEITMEANPGTIEAERFAGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIG
LNSFNLDLMHGLPDQSIEQALADLDKAIELNPPHLSWYQLTIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQNMVKPYLDSEQLVEEIDRPFE
FFMNRFRLMEACPKQDFIDTTGLPLSFIETTIQWAVEMGYLNDNETSWQITEKGKLFLNDLLEAFMAEE

Sequences:

>Translated_389_residues
MLTPPALSLYVHIPWCVQKCPYCDFNSHTLKEQIPEQMYINALLEDLDRDIEKYQLHRAPRPLHSIFIGGGTPSLISAEG
IRDLLQGIEKRIPFTPSIEITMEANPGTIEAERFAGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIG
LNSFNLDLMHGLPDQSIEQALADLDKAIELNPPHLSWYQLTIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQNMVKPYLDSEQLVEEIDRPFE
FFMNRFRLMEACPKQDFIDTTGLPLSFIETTIQWAVEMGYLNDNETSWQITEKGKLFLNDLLEAFMAEE
>Mature_389_residues
MLTPPALSLYVHIPWCVQKCPYCDFNSHTLKEQIPEQMYINALLEDLDRDIEKYQLHRAPRPLHSIFIGGGTPSLISAEG
IRDLLQGIEKRIPFTPSIEITMEANPGTIEAERFAGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIG
LNSFNLDLMHGLPDQSIEQALADLDKAIELNPPHLSWYQLTIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQY
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQNMVKPYLDSEQLVEEIDRPFE
FFMNRFRLMEACPKQDFIDTTGLPLSFIETTIQWAVEMGYLNDNETSWQITEKGKLFLNDLLEAFMAEE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=273, Percent_Identity=34.0659340659341, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1789325, Length=388, Percent_Identity=63.659793814433, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI87082341, Length=252, Percent_Identity=32.9365079365079, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44559; Mature: 44559

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPPALSLYVHIPWCVQKCPYCDFNSHTLKEQIPEQMYINALLEDLDRDIEKYQLHRAP
CCCCCCEEEEEECCHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
RPLHSIFIGGGTPSLISAEGIRDLLQGIEKRIPFTPSIEITMEANPGTIEAERFAGYRKA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHCCHHHC
GVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIGLNSFNLDLMHGLPDQSIEQA
CCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHH
LADLDKAIELNPPHLSWYQLTIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQY
HHHHHHHEECCCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQN
EECCCCCCCCCCCCCCCEEEECCEEEECCCCCCCEEECCCEEEEEEECCCCCHHHHHHHH
MVKPYLDSEQLVEEIDRPFEFFMNRFRLMEACPKQDFIDTTGLPLSFIETTIQWAVEMGY
HHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LNDNETSWQITEKGKLFLNDLLEAFMAEE
CCCCCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTPPALSLYVHIPWCVQKCPYCDFNSHTLKEQIPEQMYINALLEDLDRDIEKYQLHRAP
CCCCCCEEEEEECCHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
RPLHSIFIGGGTPSLISAEGIRDLLQGIEKRIPFTPSIEITMEANPGTIEAERFAGYRKA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHCCHHHC
GVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIGLNSFNLDLMHGLPDQSIEQA
CCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHH
LADLDKAIELNPPHLSWYQLTIEPNTMFYYKPPALPDDDQLWDIFERGHQKLTQAGYVQY
HHHHHHHEECCCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
EISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIIRTTKIKHPKGYLAAHQN
EECCCCCCCCCCCCCCCEEEECCEEEECCCCCCCEEECCCEEEEEEECCCCCHHHHHHHH
MVKPYLDSEQLVEEIDRPFEFFMNRFRLMEACPKQDFIDTTGLPLSFIETTIQWAVEMGY
HHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LNDNETSWQITEKGKLFLNDLLEAFMAEE
CCCCCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]