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The map label for this gene is can [H]

Identifier: 37680952

GI number: 37680952

Start: 2821886

End: 2822596

Strand: Direct

Name: can [H]

Synonym: VV2768

Alternate gene names: 37680952

Gene position: 2821886-2822596 (Clockwise)

Preceding gene: 37680948

Following gene: 37680954

Centisome position: 84.12

GC content: 45.71

Gene sequence:

>711_bases
GTGTATAGTGATGCAAGAATTTTTAGGGAAGTAAGACGCAACATGCCGGAAATCAAGCAATTATTTGAAAACAACTCAAA
ATGGTCCGAAGAGATCAAATCGCATCAACCGGAGTATTTTTCCAAGTTAGAAGAAGGGCAAAACCCCGGCTTTCTCTGGA
TTGGGTGTTCCGACAGTCGCGTTCCTGCAGAGCGCTTGACTGGGCTTTATTCGGGTGAACTATTTGTTCACCGTAATGTG
GCAAACCAAGTGATCCATACCGATTTAAACTGCCTCTCGGTTGTGCAATACGCCGTCGACGTGTTGAAAGTTAAACACAT
CATCATCTGTGGTCATTACGGCTGTGGAGGGGTGAACGCTGCGATTGAAAATCCGCGCCTTGGTTTGATCAATAACTGGC
TACTGCACATCCGCGATCTCTACCTCAAACATCGCAATTGGTTAGGTGAACTACCAAAAGAAAAATGGGGCGACAAACTG
TGTGAAATTAACGTCGCAGAGCAGGTCTACAACTTAGGTAATTCTACTATTATGGAAAGCGCTTGGGAGCGTGGACAAGA
TGTGGAAATTCACGGCGTTGTCTATGGCATTGGTGATGGCCGCCTACAAGACATTGGCGTACGTTGCTACAGCAGAGAGT
CACTCGAAGTCAACTATCAGGCTGCAATGGCAAAAATCCTCAATAGCGATGTGATGAAGTTTCACGAATAG

Upstream 100 bases:

>100_bases
TTGTGGTTTGGTTAACGGCTAAGTTTATGATTTTTTATGCCATAACTAGTCAGATGAGTACTTTTCTGCCAATTTATTTC
GGGCGGTAAATTGTAACATT

Downstream 100 bases:

>100_bases
CGCCATCGTTAGACCGCCGACACAATCCGTGTTCTAGAGATAAAAATGCAATGGCCCGCTGTATCAGCGGGCCATTATTA
TTTATGAGTACCACTTACTC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MYSDARIFREVRRNMPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNV
ANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKL
CEINVAEQVYNLGNSTIMESAWERGQDVEIHGVVYGIGDGRLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE

Sequences:

>Translated_236_residues
MYSDARIFREVRRNMPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNV
ANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKL
CEINVAEQVYNLGNSTIMESAWERGQDVEIHGVVYGIGDGRLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
>Mature_236_residues
MYSDARIFREVRRNMPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNV
ANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKL
CEINVAEQVYNLGNSTIMESAWERGQDVEIHGVVYGIGDGRLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=66.5094339622642, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI1786534, Length=192, Percent_Identity=29.6875, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=30.1507537688442, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 27107; Mature: 27107

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSDARIFREVRRNMPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSR
CCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCC
VPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNA
CCHHHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
AIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGNSTIMES
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHEEEHHHHHHHHCCCHHHHHH
AWERGQDVEIHGVVYGIGDGRLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
HHHCCCCEEEEEEEEECCCCCCHHHCCEEECCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYSDARIFREVRRNMPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSR
CCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCC
VPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNA
CCHHHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
AIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGNSTIMES
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHEEEHHHHHHHHCCCHHHHHH
AWERGQDVEIHGVVYGIGDGRLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
HHHCCCCEEEEEEEEECCCCCCHHHCCEEECCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]