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The map label for this gene is panC

Identifier: 37680948

GI number: 37680948

Start: 2817151

End: 2818056

Strand: Direct

Name: panC

Synonym: VV2764

Alternate gene names: 37680948

Gene position: 2817151-2818056 (Clockwise)

Preceding gene: 37680947

Following gene: 37680952

Centisome position: 83.98

GC content: 48.9

Gene sequence:

>906_bases
ATGCAAACCTTTGCCGAAATTTCAGCCCTTCGTGAACAGATCAAAACGTTCAAACGCGAAGGACGTCGAATTGCTTTTGT
TCCAACCATGGGCAATTTACATGAAGGCCACTTGACGCTCGTGCGTAAAGCTCGTGAGCACGCCGATATCGTGGTTGTCA
GTATTTTTGTTAACCCAATGCAGTTTGATCGCGCTGACGATTTAAATAATTATCCAAGAACATTGGAAGACGATCTCAGT
AAACTCAACGGTGAAGCGGTTGAACTGGTCTTTACTCCAACACCTGAAATGATCTACCCAGAAGGCTTGGATAAGCAGAC
TCTCGTTGAAGTCCCTAGCTTATCAACCATGCTGGAAGGGGCATCGCGCCCAGGCCATTTCCGCGGCGTTGCGACAGTGG
TTACTAAGCTATTTAACATTGTTCAGCCGGATGTGGCTTGCTTTGGTGAAAAAGACTTCCAACAGCTCGCTATCATTCGC
AAAATGACCACCGATTTGGCAATGGACATTGAGATTATTGGTGTGCCTACCGTGCGTGAAATGGATGGCCTTGCCATGAG
CTCTCGCAATGGCTTATTGACCATTGATGAGCGCCAACGTGCGCCTGTCTTGGCTCGCACCATGCGTTGGATCAGCAGTG
CTATCCGTGGTGGCCGTGACGATTTTGCATCGATCATCGAAGACGCCAGCGATCAATTGCGCGCCGCAGGCTTGCACCCC
GATGAAATTTTCATCCGTGATGCACGTACTCTACAAGCGGTCAACACGGAGAGCACGCAAGCCGTTATTCTGATGTCCGC
TTTCTTGGGCAAAGCTCGCCTGATCGACAATCAAGTGGTTGAGTTGGTGAAAGACAGCAAAGAAGAAGTCGACAGCATCG
AATCAGAAAGTGAAAACAGTCACTGA

Upstream 100 bases:

>100_bases
AACAGGAGATATGCGCAAAGCCGTGGCGCTGTACATGGAACAAGTACAAGCAGGCACCTTCCCTGATGAAGCGCACACCA
TTGCTTAGAGGATAATGTAG

Downstream 100 bases:

>100_bases
TGTCTCATCACTGACCTAAACACTTCCCGCACAAAGAATAAAGGGATTGCCATCGGCAATCCCTTTTTGTTATCTGTGAA
CTGAACATGAGTTTTCGTTA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADIVVVSIFVNPMQFDRADDLNNYPRTLEDDLS
KLNGEAVELVFTPTPEMIYPEGLDKQTLVEVPSLSTMLEGASRPGHFRGVATVVTKLFNIVQPDVACFGEKDFQQLAIIR
KMTTDLAMDIEIIGVPTVREMDGLAMSSRNGLLTIDERQRAPVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHP
DEIFIRDARTLQAVNTESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSIESESENSH

Sequences:

>Translated_301_residues
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADIVVVSIFVNPMQFDRADDLNNYPRTLEDDLS
KLNGEAVELVFTPTPEMIYPEGLDKQTLVEVPSLSTMLEGASRPGHFRGVATVVTKLFNIVQPDVACFGEKDFQQLAIIR
KMTTDLAMDIEIIGVPTVREMDGLAMSSRNGLLTIDERQRAPVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHP
DEIFIRDARTLQAVNTESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSIESESENSH
>Mature_301_residues
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADIVVVSIFVNPMQFDRADDLNNYPRTLEDDLS
KLNGEAVELVFTPTPEMIYPEGLDKQTLVEVPSLSTMLEGASRPGHFRGVATVVTKLFNIVQPDVACFGEKDFQQLAIIR
KMTTDLAMDIEIIGVPTVREMDGLAMSSRNGLLTIDERQRAPVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHP
DEIFIRDARTLQAVNTESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSIESESENSH

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=273, Percent_Identity=59.3406593406593, Blast_Score=340, Evalue=9e-95,
Organism=Saccharomyces cerevisiae, GI6322046, Length=307, Percent_Identity=38.4364820846906, Blast_Score=183, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 33609; Mature: 33609

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADIVVVSIFVNPM
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCH
QFDRADDLNNYPRTLEDDLSKLNGEAVELVFTPTPEMIYPEGLDKQTLVEVPSLSTMLEG
HCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHC
ASRPGHFRGVATVVTKLFNIVQPDVACFGEKDFQQLAIIRKMTTDLAMDIEIIGVPTVRE
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHH
MDGLAMSSRNGLLTIDERQRAPVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHP
HCCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DEIFIRDARTLQAVNTESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSIESESENS
HHEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
H
C
>Mature Secondary Structure
MQTFAEISALREQIKTFKREGRRIAFVPTMGNLHEGHLTLVRKAREHADIVVVSIFVNPM
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCH
QFDRADDLNNYPRTLEDDLSKLNGEAVELVFTPTPEMIYPEGLDKQTLVEVPSLSTMLEG
HCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHC
ASRPGHFRGVATVVTKLFNIVQPDVACFGEKDFQQLAIIRKMTTDLAMDIEIIGVPTVRE
CCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHH
MDGLAMSSRNGLLTIDERQRAPVLARTMRWISSAIRGGRDDFASIIEDASDQLRAAGLHP
HCCCEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DEIFIRDARTLQAVNTESTQAVILMSAFLGKARLIDNQVVELVKDSKEEVDSIESESENS
HHEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA