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The map label for this gene is gluQ [H]

Identifier: 37680944

GI number: 37680944

Start: 2813479

End: 2814390

Strand: Direct

Name: gluQ [H]

Synonym: VV2760

Alternate gene names: 37680944

Gene position: 2813479-2814390 (Clockwise)

Preceding gene: 37680943

Following gene: 37680945

Centisome position: 83.87

GC content: 47.26

Gene sequence:

>912_bases
ATGCTCCCTTTTTGTTTTGAGATGACATCCATGAGCTACATCGGTCGTTTTGCCCCTTCCCCATCAGGCCCATTGCATTT
TGGCTCCTTGATTGCTGCTTTAGGCAGCTACTTTCAAGCCAAATCTCAACATGGTCAGTGGTTAGTGCGCATTGAAGATC
TCGATCCGCCTCGAGAAATGCCGGGGGCGGCGGATTTGATTTTAAAAACGCTCGAAACTTATCACTTATTTTGGGATGGT
GAAGTGGTTTACCAAAGCCAGCGTCATCACCTCTATCAAGCGCAAATTGACCACTGGCTGCAAAGTGGCCAAGCCTATTA
CTGCCAGTGCAGTCGCAAGCAGATCAAAGAAATGGGTGGCTATTACAACGGCCATTGCCAAGAATTGCATTTGGATGCAG
GGGCTATTCGTCTCAAAATGACGCAGCCAATCACTCATTTTGACGATCTTCGTCATGGGCAGATGCACATTCCTCTCGAA
CTCGCGCAAGAAGATTTCATCATCAAGCGCCGTGATGGTTTGTTTGCCTATAATCTTGCAGTGGTATTGGACGATATCGA
TCAGGGTGTGACCGAAGTGGTGCGTGGCGCTGATTTAATCGAACCAACTGGTCGTCAAATCAGCTTGTACCACATGCTCG
GTCAAGTTCCTGTCCGATATTTGCACTTGCCACTGGCAATGGATAAAAATGGCAACAAACTCTCCAAACAAAATCATGCC
ACTGGCATTGATTTGACACATCCAGCCTCTATGATTCTTGAAGCGATGGCGTTTCTAGGTTTTGCCATTCCCAAAGAACT
TCATCAGGCCAATTTGGATGAAATTCTGCGTTGGGGTGTACAAAATTGGCGCCTAAATCAGTTGCCCGAATCGCTAGAAA
TCACGGCGCGATTCTCAAATGGCACGGCGTGA

Upstream 100 bases:

>100_bases
CAACTGCCGATCTTTGTATCGACTGTAAAACGCTTGCAGAGATCAAAGAGAAGCAAATGCAAGGTTAAGAATAACCGGCC
TAACATGATTAAGGGAGCTG

Downstream 100 bases:

>100_bases
GCTATTATAGGGCGCAAATTCAGGCCAAATCGGCGTAAAAAACTAACCCATGCAAAGTGATGACCACTCACTGTTGCCAG
ATGCACATGAATAAAAACGA

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLPFCFEMTSMSYIGRFAPSPSGPLHFGSLIAALGSYFQAKSQHGQWLVRIEDLDPPREMPGAADLILKTLETYHLFWDG
EVVYQSQRHHLYQAQIDHWLQSGQAYYCQCSRKQIKEMGGYYNGHCQELHLDAGAIRLKMTQPITHFDDLRHGQMHIPLE
LAQEDFIIKRRDGLFAYNLAVVLDDIDQGVTEVVRGADLIEPTGRQISLYHMLGQVPVRYLHLPLAMDKNGNKLSKQNHA
TGIDLTHPASMILEAMAFLGFAIPKELHQANLDEILRWGVQNWRLNQLPESLEITARFSNGTA

Sequences:

>Translated_303_residues
MLPFCFEMTSMSYIGRFAPSPSGPLHFGSLIAALGSYFQAKSQHGQWLVRIEDLDPPREMPGAADLILKTLETYHLFWDG
EVVYQSQRHHLYQAQIDHWLQSGQAYYCQCSRKQIKEMGGYYNGHCQELHLDAGAIRLKMTQPITHFDDLRHGQMHIPLE
LAQEDFIIKRRDGLFAYNLAVVLDDIDQGVTEVVRGADLIEPTGRQISLYHMLGQVPVRYLHLPLAMDKNGNKLSKQNHA
TGIDLTHPASMILEAMAFLGFAIPKELHQANLDEILRWGVQNWRLNQLPESLEITARFSNGTA
>Mature_303_residues
MLPFCFEMTSMSYIGRFAPSPSGPLHFGSLIAALGSYFQAKSQHGQWLVRIEDLDPPREMPGAADLILKTLETYHLFWDG
EVVYQSQRHHLYQAQIDHWLQSGQAYYCQCSRKQIKEMGGYYNGHCQELHLDAGAIRLKMTQPITHFDDLRHGQMHIPLE
LAQEDFIIKRRDGLFAYNLAVVLDDIDQGVTEVVRGADLIEPTGRQISLYHMLGQVPVRYLHLPLAMDKNGNKLSKQNHA
TGIDLTHPASMILEAMAFLGFAIPKELHQANLDEILRWGVQNWRLNQLPESLEITARFSNGTA

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=249, Percent_Identity=34.136546184739, Blast_Score=127, Evalue=9e-30,
Organism=Escherichia coli, GI226510925, Length=308, Percent_Identity=54.5454545454545, Blast_Score=334, Evalue=5e-93,
Organism=Escherichia coli, GI1788743, Length=252, Percent_Identity=35.7142857142857, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71993394, Length=250, Percent_Identity=31.2, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324540, Length=290, Percent_Identity=31.3793103448276, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24665321, Length=260, Percent_Identity=31.5384615384615, Blast_Score=121, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 34466; Mature: 34466

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPFCFEMTSMSYIGRFAPSPSGPLHFGSLIAALGSYFQAKSQHGQWLVRIEDLDPPREM
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHC
PGAADLILKTLETYHLFWDGEVVYQSQRHHLYQAQIDHWLQSGQAYYCQCSRKQIKEMGG
CCHHHHHHHHHHHHEEEECCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCC
YYNGHCQELHLDAGAIRLKMTQPITHFDDLRHGQMHIPLELAQEDFIIKRRDGLFAYNLA
CCCCCCEEEEECCCEEEEEECCCCHHHHHCCCCCEECCHHHCCCCCEEEECCCEEEEEHH
VVLDDIDQGVTEVVRGADLIEPTGRQISLYHMLGQVPVRYLHLPLAMDKNGNKLSKQNHA
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCHHHEEEEEEECCCCCCCCCCCCC
TGIDLTHPASMILEAMAFLGFAIPKELHQANLDEILRWGVQNWRLNQLPESLEITARFSN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHCCCCCEEEEEEECC
GTA
CCC
>Mature Secondary Structure
MLPFCFEMTSMSYIGRFAPSPSGPLHFGSLIAALGSYFQAKSQHGQWLVRIEDLDPPREM
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHC
PGAADLILKTLETYHLFWDGEVVYQSQRHHLYQAQIDHWLQSGQAYYCQCSRKQIKEMGG
CCHHHHHHHHHHHHEEEECCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCC
YYNGHCQELHLDAGAIRLKMTQPITHFDDLRHGQMHIPLELAQEDFIIKRRDGLFAYNLA
CCCCCCEEEEECCCEEEEEECCCCHHHHHCCCCCEECCHHHCCCCCEEEECCCEEEEEHH
VVLDDIDQGVTEVVRGADLIEPTGRQISLYHMLGQVPVRYLHLPLAMDKNGNKLSKQNHA
HHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHCCHHHEEEEEEECCCCCCCCCCCCC
TGIDLTHPASMILEAMAFLGFAIPKELHQANLDEILRWGVQNWRLNQLPESLEITARFSN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHCCCCCEEEEEEECC
GTA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA