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The map label for this gene is hutI [H]

Identifier: 37680133

GI number: 37680133

Start: 1937242

End: 1938462

Strand: Direct

Name: hutI [H]

Synonym: VV1949

Alternate gene names: 37680133

Gene position: 1937242-1938462 (Clockwise)

Preceding gene: 37680132

Following gene: 37680134

Centisome position: 57.75

GC content: 50.53

Gene sequence:

>1221_bases
ATGGATCTGTTGCTTACCAACGCACGCCTTGTCACTTTGCAATCAGGGGAAATGGGTTATCAACCCAGCACGCCGATGTC
GATTGGCATTAAGGCGGGGAAGATCCATTATCTAGGCATTGACACGGCACTGGCTGCTACTAAGCAAATTGATCTAAAAG
GTAAGCTGGTTACTCCCGGCCTTATCGACTGCCACACACATCTTGTTTACGCGGGTAATCGGTCCAACGAATTTGAAATG
CGATTGCAGGGCGTTCCCTATCAAGAAATCGCTCGCCAAGGCGGCGGCATTCTTTCTACCGTTTACGGGACACGCCAAGC
CAGTGAAGCCCAGTTACTCGAACAAACACTACCACGTCTTGATGGCTTACTTGCCAGTGGCGTCACGTCGGTTGAAATCA
AATCGGGCTATGGATTAACACTGGTTGATGAAATCAAAATGCTGCGAGTGGCAAAGTCCTTATCACAGCATCGATTGGTG
AAGGTCACACCAACACTGTTAGCCGCCCATGCCCTCCCCCCTGAATTTACTGGCCGTGCGAACGACTACATCGAGTTTAT
TTGCCAAGAGATCATCCCAGTGGTGGCCGAAGAACAGTTAGCCACCAGCGTCGATGTATTTTGTGAGTCAATTGGGTTTG
ATTTGGCACAAACGGAAAGGGTCTATGCCTGCGCTGTCGACCACGGGCTGCGTGTCAAAGGGCACACAGAGCAACTGTCA
AATTTGGGCGGAACCGCTTTAACTGCTCGTTATCAGGGGCTTTCTGCTGACCATATTGAATTTCTTGATCGAGCAGGCGT
CGAAGCACTTGCCCGTTCATCGACCGTCGCGACTCTATTGCCTGGGGCGTTCTATTTTCTGCGTGAAACCCAATTGCCGC
CGATTGAACTATTGCGTCAGTTTGGTGTGCCCATGGCCATTGCCAGCGATGTTAACCCCGGCACCTCACCATTTTGTGAT
TTAACCTTAATGATGAACATGGCTTGCACCCTCTTTCGTTTAACGCCAGAAGAAGCTTTACGTGGCGTCACTCAACATGC
GGCGCAAGCATTGGGCTATGCGGAGAGTCGAGGGCAAATCAAAACAGGTTATGACGCGGATCTCGCCATCTGGCAGATCG
AGCATCCCGCCGATCTCAGTTATCAAGTCGGAACTCAGCGTCTCTTTGCAAGAGTCGTTGATGGTCAATTCGAGCAACAC
AAGGAGTGTTGTGATGAGTAA

Upstream 100 bases:

>100_bases
TTTGATCACATTTCAGCAACATTCACCTTGTCACAACGGTTATTTTCTCCTATTTATTTGTATATACATTTAGTCAATAC
AAATCATTGGAACCTTAATC

Downstream 100 bases:

>100_bases
ACATTTTTTTCTTCATAATGAATTTCATTGGCAAGGTCGCCACGATGCGGAAGACGGTGCCGCGGGTTCGCGTGTTCATC
ATGTGGTGCAGCAGATTGAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYGTRQASEAQLLEQTLPRLDGLLASGVTSVEIKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPVVAEEQLATSVDVFCESIGFDLAQTERVYACAVDHGLRVKGHTEQLS
NLGGTALTARYQGLSADHIEFLDRAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQHAAQALGYAESRGQIKTGYDADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE

Sequences:

>Translated_406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYGTRQASEAQLLEQTLPRLDGLLASGVTSVEIKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPVVAEEQLATSVDVFCESIGFDLAQTERVYACAVDHGLRVKGHTEQLS
NLGGTALTARYQGLSADHIEFLDRAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQHAAQALGYAESRGQIKTGYDADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE
>Mature_406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYGTRQASEAQLLEQTLPRLDGLLASGVTSVEIKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPVVAEEQLATSVDVFCESIGFDLAQTERVYACAVDHGLRVKGHTEQLS
NLGGTALTARYQGLSADHIEFLDRAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQHAAQALGYAESRGQIKTGYDADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=340, Percent_Identity=36.7647058823529, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17555004, Length=359, Percent_Identity=32.5905292479109, Blast_Score=194, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 44267; Mature: 44267

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPG
CCEEEECCEEEEEECCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHEECCCCEEECCC
LIDCHTHLVYAGNRSNEFEMRLQGVPYQEIARQGGGILSTVYGTRQASEAQLLEQTLPRL
EEECCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHH
DGLLASGVTSVEIKSGYGLTLVDEIKMLRVAKSLSQHRLVKVTPTLLAAHALPPEFTGRA
HHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCH
NDYIEFICQEIIPVVAEEQLATSVDVFCESIGFDLAQTERVYACAVDHGLRVKGHTEQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCEECCCHHHHH
NLGGTALTARYQGLSADHIEFLDRAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQ
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHH
FGVPMAIASDVNPGTSPFCDLTLMMNMACTLFRLTPEEALRGVTQHAAQALGYAESRGQI
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCHHCCCCE
KTGYDADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQHKECCDE
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPG
CCEEEECCEEEEEECCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHEECCCCEEECCC
LIDCHTHLVYAGNRSNEFEMRLQGVPYQEIARQGGGILSTVYGTRQASEAQLLEQTLPRL
EEECCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHH
DGLLASGVTSVEIKSGYGLTLVDEIKMLRVAKSLSQHRLVKVTPTLLAAHALPPEFTGRA
HHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCH
NDYIEFICQEIIPVVAEEQLATSVDVFCESIGFDLAQTERVYACAVDHGLRVKGHTEQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCEECCCHHHHH
NLGGTALTARYQGLSADHIEFLDRAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQ
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHH
FGVPMAIASDVNPGTSPFCDLTLMMNMACTLFRLTPEEALRGVTQHAAQALGYAESRGQI
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCHHCCCCE
KTGYDADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQHKECCDE
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA