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The map label for this gene is queC

Identifier: 37679725

GI number: 37679725

Start: 1581685

End: 1582383

Strand: Direct

Name: queC

Synonym: VV1541

Alternate gene names: 37679725

Gene position: 1581685-1582383 (Clockwise)

Preceding gene: 37679724

Following gene: 37679730

Centisome position: 47.15

GC content: 45.21

Gene sequence:

>699_bases
ATGAACAAAGCCGTTGTGGTTTTTAGTGGTGGTCAGGATTCGACGACCTGTTTAGTCAAAGCACTCAATGAATTTGATGA
AGTGCATGCCATCACGTTTGATTATGGCCAACGTCACCGTCTTGAAATCGAAGTGGCGCAAAATCTGGCGAAAGAACTGG
GTGTAGCTGCACACAAAGTGATGGATGTGACGCTGCTCAATGAGTTGGCCATTAGTTCACTGACTCGCGACGATATTCCT
GTATCTCATGAACTGCAGGAGAATGGTTTACCCAACTCGTTTGTTCCTGGTCGTAACATTCTTTTCCTCACTTTGGCGGG
CATTTACGCTTATCAAATTGGCGCAGAGACGATCATTACTGGAGTGTGTGAAACCGATTTTTCTGGCTATCCAGATTGTC
GTGATGACTTTGTCAAAGCGATGAACAGTGCGCTTGTGAAGGGCATGGATAAGCCATTAGTGATCCAAACACCACTCATG
TGGCTCAACAAAGCAGAGACGTGGGCGCTTGCGGATCAAAATAACGCTTTGCAATTGGTCAGAGAAAAAACCTTAACGTG
TTACAACGGCATCGTTGGTGATGGTTGTGGTGATTGTCCTTCTTGTCACTTACGTAAAGTGGGTCTCAATGACTATTTAG
ACAACCGTGAGGCGATCATGGCTTCTTTAGTTGAAAAGCAGCACGCCGAATCTAAATAA

Upstream 100 bases:

>100_bases
GAGAGCCACTCAGTTGTGCATCGACACCTGTATTAAGCGCAATTGGCGTTTGTCGATTCAAACACATAAGTATCTGAGTA
TCGCGTAAGAGGGATTGTTT

Downstream 100 bases:

>100_bases
ACGAAACAGAAGATGACGGCAATGCTGTTGAGTTGCGATAATTCGCTGGCGCCTTTAGCGCACAGGAATTATCGCTTTTT
CATTTTCTGTTCAATCAAAT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKAVVVFSGGQDSTTCLVKALNEFDEVHAITFDYGQRHRLEIEVAQNLAKELGVAAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETIITGVCETDFSGYPDCRDDFVKAMNSALVKGMDKPLVIQTPLM
WLNKAETWALADQNNALQLVREKTLTCYNGIVGDGCGDCPSCHLRKVGLNDYLDNREAIMASLVEKQHAESK

Sequences:

>Translated_232_residues
MNKAVVVFSGGQDSTTCLVKALNEFDEVHAITFDYGQRHRLEIEVAQNLAKELGVAAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETIITGVCETDFSGYPDCRDDFVKAMNSALVKGMDKPLVIQTPLM
WLNKAETWALADQNNALQLVREKTLTCYNGIVGDGCGDCPSCHLRKVGLNDYLDNREAIMASLVEKQHAESK
>Mature_232_residues
MNKAVVVFSGGQDSTTCLVKALNEFDEVHAITFDYGQRHRLEIEVAQNLAKELGVAAHKVMDVTLLNELAISSLTRDDIP
VSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETIITGVCETDFSGYPDCRDDFVKAMNSALVKGMDKPLVIQTPLM
WLNKAETWALADQNNALQLVREKTLTCYNGIVGDGCGDCPSCHLRKVGLNDYLDNREAIMASLVEKQHAESK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=67.84140969163, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_VIBVY (Q7ML86)

Other databases:

- EMBL:   BA000037
- RefSeq:   NP_934334.1
- ProteinModelPortal:   Q7ML86
- SMR:   Q7ML86
- STRING:   Q7ML86
- GeneID:   2624347
- GenomeReviews:   BA000037_GR
- KEGG:   vvy:VV1541
- NMPDR:   fig|196600.1.peg.1609
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   PRK11106
- BioCyc:   VVUL196600:VV1541-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25518; Mature: 25518

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAVVVFSGGQDSTTCLVKALNEFDEVHAITFDYGQRHRLEIEVAQNLAKELGVAAHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
MDVTLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETIIT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHH
GVCETDFSGYPDCRDDFVKAMNSALVKGMDKPLVIQTPLMWLNKAETWALADQNNALQLV
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEECCCCHHHHH
REKTLTCYNGIVGDGCGDCPSCHLRKVGLNDYLDNREAIMASLVEKQHAESK
HHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKAVVVFSGGQDSTTCLVKALNEFDEVHAITFDYGQRHRLEIEVAQNLAKELGVAAHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
MDVTLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETIIT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHH
GVCETDFSGYPDCRDDFVKAMNSALVKGMDKPLVIQTPLMWLNKAETWALADQNNALQLV
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEECCCCHHHHH
REKTLTCYNGIVGDGCGDCPSCHLRKVGLNDYLDNREAIMASLVEKQHAESK
HHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA