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The map label for this gene is phoE [H]

Identifier: 37679661

GI number: 37679661

Start: 1513655

End: 1514293

Strand: Direct

Name: phoE [H]

Synonym: VV1477

Alternate gene names: 37679661

Gene position: 1513655-1514293 (Clockwise)

Preceding gene: 37679660

Following gene: 37679662

Centisome position: 45.12

GC content: 49.3

Gene sequence:

>639_bases
ATGGAAGTGATCTTACTGCGTCATGGCAAAACAGCAGCGGAAGCGGGTTTATTTGGCCGAACCGATGCCAAGGTACCGGC
GGATCGTCAGCAAGCGATTGCCGAAGCGTTGTTCGCTCAGCATGACGATGTTGAACTCATCGTGAGCTCGCCTCTCTCTC
GATGCCATGAGTTGGCTGAGTTGCTGGGTCAACAACACCATTGGCCAATTCAATTGCAAGCAGACCTACAAGAGATGGAC
TTTGGTTTGTTAGACGGAGTGCCTTTTGATACTCAGGACTATCCGTGGCCTCTACTCAACGCCTTTTGGCAAGACCCTGC
CAATGCCTCTTTGCCAGAGGGCGAGACGTTGGCTGAATTTCAGCAAAGGGTAGTGCAGTGCTGGTCGCAAATCATCAGCG
CAGAACATCGCAAAGTGTTAATCATCACTCATGGTGGTGTAATTCGACTTATCTTAGCTCACCTTTTGGGTGTAGACTGG
CAAAGCCCTCACTGGTATCAAAACTTGGCCATTGAGAACGCAAGTCTGACACACATAACGATTTTTACCGATAGTGACCA
AACGCAGTTTCCGACAGTCAAAATGATCGGGATGCCTCTCTCTATCAGGGAAGAACAGACGAATCATCCAGTCGATTAG

Upstream 100 bases:

>100_bases
TATGAATCAATCACTTGCTCAGGCGTGTGACAACGTCACCCTAATCGCAGCGGGGTTACCCCTCATACTGAAATCGAGTG
GTCATCAATAGGGAAATACG

Downstream 100 bases:

>100_bases
TCACAGATTCATAAGGAACACAGAATGACCGCGCCAAGCTGGGATCTTTCTATTGCCTATGCAGATTTAACCGATGTTCG
TATCGAACAAGATATCGAAC

Product: fructose-2;6-bisphosphatase

Products: alpha-ribazole; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MEVILLRHGKTAAEAGLFGRTDAKVPADRQQAIAEALFAQHDDVELIVSSPLSRCHELAELLGQQHHWPIQLQADLQEMD
FGLLDGVPFDTQDYPWPLLNAFWQDPANASLPEGETLAEFQQRVVQCWSQIISAEHRKVLIITHGGVIRLILAHLLGVDW
QSPHWYQNLAIENASLTHITIFTDSDQTQFPTVKMIGMPLSIREEQTNHPVD

Sequences:

>Translated_212_residues
MEVILLRHGKTAAEAGLFGRTDAKVPADRQQAIAEALFAQHDDVELIVSSPLSRCHELAELLGQQHHWPIQLQADLQEMD
FGLLDGVPFDTQDYPWPLLNAFWQDPANASLPEGETLAEFQQRVVQCWSQIISAEHRKVLIITHGGVIRLILAHLLGVDW
QSPHWYQNLAIENASLTHITIFTDSDQTQFPTVKMIGMPLSIREEQTNHPVD
>Mature_212_residues
MEVILLRHGKTAAEAGLFGRTDAKVPADRQQAIAEALFAQHDDVELIVSSPLSRCHELAELLGQQHHWPIQLQADLQEMD
FGLLDGVPFDTQDYPWPLLNAFWQDPANASLPEGETLAEFQQRVVQCWSQIISAEHRKVLIITHGGVIRLILAHLLGVDW
QSPHWYQNLAIENASLTHITIFTDSDQTQFPTVKMIGMPLSIREEQTNHPVD

Specific function: Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activtiy [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.73

Molecular weight: Translated: 23907; Mature: 23907

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVILLRHGKTAAEAGLFGRTDAKVPADRQQAIAEALFAQHDDVELIVSSPLSRCHELAE
CEEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHH
LLGQQHHWPIQLQADLQEMDFGLLDGVPFDTQDYPWPLLNAFWQDPANASLPEGETLAEF
HHCCCCCCCEEEECCHHHCCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHH
QQRVVQCWSQIISAEHRKVLIITHGGVIRLILAHLLGVDWQSPHWYQNLAIENASLTHIT
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEE
IFTDSDQTQFPTVKMIGMPLSIREEQTNHPVD
EEECCCCCCCCEEEEECCCCEECCCCCCCCCC
>Mature Secondary Structure
MEVILLRHGKTAAEAGLFGRTDAKVPADRQQAIAEALFAQHDDVELIVSSPLSRCHELAE
CEEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHH
LLGQQHHWPIQLQADLQEMDFGLLDGVPFDTQDYPWPLLNAFWQDPANASLPEGETLAEF
HHCCCCCCCEEEECCHHHCCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHH
QQRVVQCWSQIISAEHRKVLIITHGGVIRLILAHLLGVDWQSPHWYQNLAIENASLTHIT
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEE
IFTDSDQTQFPTVKMIGMPLSIREEQTNHPVD
EEECCCCCCCCEEEEECCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alpha-ribazole 5'-phosphate; H2O

Specific reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]