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The map label for this gene is torA [H]

Identifier: 37679559

GI number: 37679559

Start: 1398142

End: 1400604

Strand: Direct

Name: torA [H]

Synonym: VV1375

Alternate gene names: 37679559

Gene position: 1398142-1400604 (Clockwise)

Preceding gene: 37679558

Following gene: 37679560

Centisome position: 41.68

GC content: 49.33

Gene sequence:

>2463_bases
ATGGCTATTACAAGAAGAAGTTTTCTTAAGGGCGTAGCAACCACAAGTGCTGCCTCTGTTATCGGTCCTAGCTTATTGGC
GTCGGCTTCTGCAAACGCAGTAGAAACAACAGGAACTTGGAAAGTATCTGGTTCTCACTGGGGCGCGTTCCGCGCCCACA
TCTACGCGGGTAAAGTTCAAGAGATCAAACCGATAGAGCTAGACCAAAACCCAACTGAGATGCTAAACGGCATCAAAGGC
ATCATCTACAGCCCTTCACGTGTGCGTTACCCAATGGTGCGCCTTGACTGGCTGAAAAAACACAAGTACAGCGCCGATAC
GCGCGGTAACAACCGTTTTGTACGTGTGACTTGGGATGAAGCGCTGGATCTGTTCTACCGTGAGCTAGAGCGCGTACAAA
AAGAGTACGGCCCTTGGGCGCTACACGCAGGCCAAACAGGTTGGAACCAAACGGGTTCATTCAACAACTGTACTGCACAT
ATGCAGCGCGCTGTTGGCATGCACGGTAACTACATCACCAAAGTGGGTGATTACTCAACCGGTGCCGGTCAAACGATTCT
GCCATACGTGCTAGGTTCTACCGAAGTATACGCACAAGGCACGTCTTGGTCTGAAATTTTAGAAAACGCAGACAACATTA
TTCTTTGGGCGAACGACCCAGTGAAAAACCTGCAAGTGGGTTGGAACTGTGAAACGCATGAATCTTACGCTTACCTTGCG
CAACTAAAAGAGAAAGTGGCCAAAGGCGAGATCAACGTGATTTCGGTTGACCCAGTTAAGAACAAAACACAGCGTTACCT
AGAGAACGATCATCTGTATGTCAACCCAATGACAGATGTACCGTTTATGTTGGCGATTGCACACGTTCTCTACACTGAAA
ACCTATACGATAAGAAGTTCATCGAAACTTACTGTCTTGGCTTTGAAGAGTTCATCAACTACGTTCAAGGCAAAACGAAG
GACAAAGTTGAGAAAACACCAGAATGGGCTGCGCCTATTTGTGGCGTGAAAGCGGACAAAATCCGTGAATTTGCCCGCAT
GCTTGTGAAAGGTCGCACTCAGATCCTGATGGGTTGGTGTATCCAACGTCAAGAGCACGGTGAACAGCCTTACTGGGCAG
CAGCGGTTGTTGCGGCAATGATTGGTCAAATCGGCTTGCCTGGCGGTGGTATCTCTTATGGTCACCACTACTCAAGTATC
GGTGTGCCTTCAACCGGTTTTGCTGGCCCTGGTGGTTTCCCTCGTAACCTTGATGCGGGCATGAAACCTAAGTGGGACAA
CAATGACTTCAATGGTTACAGCCGTACTATCCCTGTTGCGCGTTGGATCGACTGTCTGCTAGAGCCAGGCAAAGAGATCA
ACTACAACGGTGGCAAAGTGAAGCTGCCAGACTTCAAGATGATGGTCATTTCGGGTTGTAACCCATGGCACCACCATCAA
GATCGCAACCGCATGAAGCAAGCGTTCCAGAAACTACAAACTGTTGTGACGATCGACTTCGCGTGGACAGCGACGTGTCG
CTTCTCAGACATCGTGCTACCAGCATGTACCCAGTGGGAACGCAATGACATCGACGTATACGGTTCATACTCAAGCCGTG
GTTTGATTGCGATGCACCGTTTGGTGGATCCACTGTTCCAATCTAAGCCAGACTTCCAAATCATGAAGGAATTGACTGAG
CGCTTTGGCCGCAGTGAAGAATACTCTCGCGGTATGAGTGAAATGGATTGGATTCGCAGCCTATACAACGATTGTAAGAA
ATCGAACGAAGGCAAGTTCGAGATGCCAGAGTTTGATGAGTTCTGGGAGAAGAGCGTACTGGACTTCGGCCAAGGTCAAC
CTTGGGTTCGTCACGCGGACTTCCGTCAAGATCCTGAAATCAACCCACTGGGTACACCTTCAGGCTTTATCGAGATCACG
TCTCGTAAGATCGGTCGTTACGGTTACGAACACTGTCAAGAGCACCCAATGTGGTTCGAAAAATCAGAACGTTCACACGG
CGGACCAGGTTCAGACAAACATCCGTTCTGGTTGCAATCTTGTCACCCAGACAAACGCCTGCACTCTCAGATGTGTGAAT
CTGAAGAGTTCCGTGCGACTTACGCAGTAAAAGGTCGTGAGCCAGTCTACATCAACCCACTTGATGCAAAAGCAAAAGGC
ATCAAAGAGGGTGATTTGGTACGCGTGTTTAATGACCGTGGTCAGCTTCTTGCTGGTGCTGTGCTAACGGACAGCTACCC
ACGTGGCGTGATTCGTATCGAAGAAGGTGCGTGGTACGGTCCCCTAAGCGAGAAAGTGGGAGCTATCTGTACTTACGGTG
ACCCTAACACACTGACTCAAGATATCGGCTCATCTGAGTTGGCACAGGCAACTTCTGCGAACACCTGTATCGTGGACTTC
GAGAAGTTCACTGGTAAAGTTCCACCAGTCACCTCATTTGGTGGTCCAATCGAAGTCGCGTAA

Upstream 100 bases:

>100_bases
TGATACGGATAGCGAAGCACTGATCTTGAAATATCTACAGAAGCACTCTTCAGATTATGCTGAAGGTCATCACTAATAAG
CATTGGATGGAGTAATTTAA

Downstream 100 bases:

>100_bases
TCGCAGCTTGATAATGAACGATAGAAGGTCTGGCATACATGCCGGACCTTTTTTTGTTTCGATAACGCAAAAATAGAATT
ATCCATTACATATTCCTTCG

Product: anaerobic dehydrogenase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MAITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQEIKPIELDQNPTEMLNGIKG
IIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDEALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAH
MQRAVGMHGNYITKVGDYSTGAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLA
QLKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKFIETYCLGFEEFINYVQGKTK
DKVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWCIQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSI
GVPSTGFAGPGGFPRNLDAGMKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQ
DRNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHRLVDPLFQSKPDFQIMKELTE
RFGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDEFWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKG
IKEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLSEKVGAICTYGDPNTLTQDIGSSELAQATSANTCIVDF
EKFTGKVPPVTSFGGPIEVA

Sequences:

>Translated_820_residues
MAITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQEIKPIELDQNPTEMLNGIKG
IIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDEALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAH
MQRAVGMHGNYITKVGDYSTGAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLA
QLKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKFIETYCLGFEEFINYVQGKTK
DKVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWCIQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSI
GVPSTGFAGPGGFPRNLDAGMKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQ
DRNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHRLVDPLFQSKPDFQIMKELTE
RFGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDEFWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEIT
SRKIGRYGYEHCQEHPMWFEKSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKG
IKEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLSEKVGAICTYGDPNTLTQDIGSSELAQATSANTCIVDF
EKFTGKVPPVTSFGGPIEVA
>Mature_819_residues
AITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQEIKPIELDQNPTEMLNGIKGI
IYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDEALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAHM
QRAVGMHGNYITKVGDYSTGAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLAQ
LKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKFIETYCLGFEEFINYVQGKTKD
KVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWCIQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSIG
VPSTGFAGPGGFPRNLDAGMKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQD
RNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHRLVDPLFQSKPDFQIMKELTER
FGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDEFWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEITS
RKIGRYGYEHCQEHPMWFEKSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKGI
KEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLSEKVGAICTYGDPNTLTQDIGSSELAQATSANTCIVDFE
KFTGKVPPVTSFGGPIEVA

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=835, Percent_Identity=51.8562874251497, Blast_Score=878, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=825, Percent_Identity=36.969696969697, Blast_Score=563, Evalue=1e-161,
Organism=Escherichia coli, GI145693196, Length=790, Percent_Identity=37.4683544303797, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI87081797, Length=865, Percent_Identity=29.2485549132948, Blast_Score=293, Evalue=4e-80,
Organism=Escherichia coli, GI171474008, Length=853, Percent_Identity=27.3153575615475, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI1787870, Length=863, Percent_Identity=27.9258400926999, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI3868721, Length=695, Percent_Identity=23.3093525179856, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 92470; Mature: 92338

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQ
CCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCEEEECCCCCCCEEEEEEECCCC
EIKPIELDQNPTEMLNGIKGIIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDE
CCCCCCCCCCHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
ALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAHMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLA
CCCCEEHHHHCCCCEEEECCCCHHHHHCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHH
QLKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFINYVQGKTKDKVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWC
HHHHHCCHHHHHHHHCCCCHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
IQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSIGVPSTGFAGPGGFPRNLDAG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEECCCEEEEEEECCCCHHHHH
DRNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHR
HHHHHHHHHHHHHHEEEEEEEEEEEEEECCEECCCCCCCCCCCEEEEECCCCCCHHHHHH
LVDPLFQSKPDFQIMKELTERFGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDE
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
FWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
KSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKG
CCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHCCCHHCCEEEEECCCCCEEECCCCHHHCC
IKEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLSEKVGAICTYGDPNTLTQ
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCEECCHHHHHCEEEECCCCCHHHH
DIGSSELAQATSANTCIVDFEKFTGKVPPVTSFGGPIEVA
HCCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
AITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQ
CCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCEEEECCCCCCCEEEEEEECCCC
EIKPIELDQNPTEMLNGIKGIIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDE
CCCCCCCCCCHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
ALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAHMQRAVGMHGNYITKVGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
GAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLA
CCCCEEHHHHCCCCEEEECCCCHHHHHCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHH
QLKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKF
HHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHH
IETYCLGFEEFINYVQGKTKDKVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWC
HHHHHCCHHHHHHHHCCCCHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
IQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSIGVPSTGFAGPGGFPRNLDAG
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQ
CCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEECCCCCEEECCCEEEEEEECCCCHHHHH
DRNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHR
HHHHHHHHHHHHHHEEEEEEEEEEEEEECCEECCCCCCCCCCCEEEEECCCCCCHHHHHH
LVDPLFQSKPDFQIMKELTERFGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDE
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
FWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEITSRKIGRYGYEHCQEHPMWFE
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
KSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKG
CCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHCCCHHCCEEEEECCCCCEEECCCCHHHCC
IKEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLSEKVGAICTYGDPNTLTQ
CCCCCEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCEECCHHHHHCEEEECCCCCHHHH
DIGSSELAQATSANTCIVDFEKFTGKVPPVTSFGGPIEVA
HCCCHHHHHHCCCCEEEEEHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]