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The map label for this gene is torC [H]

Identifier: 37679558

GI number: 37679558

Start: 1396933

End: 1398117

Strand: Direct

Name: torC [H]

Synonym: VV1374

Alternate gene names: 37679558

Gene position: 1396933-1398117 (Clockwise)

Preceding gene: 37679555

Following gene: 37679559

Centisome position: 41.64

GC content: 47.26

Gene sequence:

>1185_bases
ATGAAATCATTGATCATTAAATTGTGGCGTACTGTAACGCGCCCAGCAGTTCATATCAGCCTTGGTGTGCTGACCGTGGG
CGGCTTCATTGCCGGTGTGATTTTCTGGGGTGGTTTTAATACCGCGTTGGAAGCGACCAACACCGAAGAGTTTTGTATCA
GTTGTCACACCATGCGTGACAATGTGTACCAAGAACTGCAAGACACTGTGCACTGGAAAAACCACTCAGGTGTTCGCGCG
ACCTGTCCTGACTGCCACGTACCCCACAACTGGACGGACAAAATTGCACGTAAAATGCAGGCGTCTAAAGAAGTTTTTGC
GCAAGTATTTGGCAACTACGATGAACCGGGCGTTTTCGAAGCTCGCCGTATCGAGCTAGCAAAACACGAATGGGATCGCT
TCTCAGCCAACAAGTCCCTTGAATGTAAAAACTGTCATAACTACGACTCGATGGATTTCGAGCAAATGTCTCCAACAGCT
CGCATCCAAATGAAGCAAGCGGCAGAGAAAGATCAAAGCTGTGTTGACTGTCACAAAGGTATCGCACACAAACTACCAGC
AGGTATGGATAGCATTGGCGGCATCGTGGGTGATCTAGAGCAGATGGCATCCAATACCGATTACTCTGTGGGTAAAGAGC
TCGTGAGTGTTCGTCACCTACCAATCTACTTTGATGCACAAGGTCAAACCGAAGCGGGTCTATTGAACCCTGCGTCTACC
GTAAAAGTATTGGAAGACAAAGGCGATTATGTCGAAATCGAGATCGACGGCTGGCGTAAAGCAAAAGGCTTTGGTCGTGT
AATCCAAGAAGACTTCGGCAAGAACATCGCAGTGGCTTCGCTACTAAAAGAAGCGTCTATGGATGACAAGATTGTCACCA
CTGGTGAAGAGAAAGTGGATGAGCTGACTGGTCTTCCATGGGAAAAAGTGGCCGCGAAAGTTTGGATCAAGAAAGAGTCA
ATGCTGAACGACATCAACCCAGTATGGGAAAAATCTCGTGAAGCATACAAAACAAACTGTTCAGTGTGTCACACACAACC
TGCAGAAGCGCACTTCGATGCCAATACTTGGCCAGGTATGTTTGACGGCATGCTAGCGTTCGTGAACCTTGATACGGATA
GCGAAGCACTGATCTTGAAATATCTACAGAAGCACTCTTCAGATTATGCTGAAGGTCATCACTAA

Upstream 100 bases:

>100_bases
GGATGTTGCAAGTTTTCTTCTTCGGACCTCCAGGTGCTCACGGCATGTAAGCCTGTGAACTTATCCCCACACTTTTGAAA
AGATTTTAAGAGAGCAGACA

Downstream 100 bases:

>100_bases
TAAGCATTGGATGGAGTAATTTAAATGGCTATTACAAGAAGAAGTTTTCTTAAGGGCGTAGCAACCACAAGTGCTGCCTC
TGTTATCGGTCCTAGCTTAT

Product: cytochrome c-type protein TorC

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKSLIIKLWRTVTRPAVHISLGVLTVGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQDTVHWKNHSGVRA
TCPDCHVPHNWTDKIARKMQASKEVFAQVFGNYDEPGVFEARRIELAKHEWDRFSANKSLECKNCHNYDSMDFEQMSPTA
RIQMKQAAEKDQSCVDCHKGIAHKLPAGMDSIGGIVGDLEQMASNTDYSVGKELVSVRHLPIYFDAQGQTEAGLLNPAST
VKVLEDKGDYVEIEIDGWRKAKGFGRVIQEDFGKNIAVASLLKEASMDDKIVTTGEEKVDELTGLPWEKVAAKVWIKKES
MLNDINPVWEKSREAYKTNCSVCHTQPAEAHFDANTWPGMFDGMLAFVNLDTDSEALILKYLQKHSSDYAEGHH

Sequences:

>Translated_394_residues
MKSLIIKLWRTVTRPAVHISLGVLTVGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQDTVHWKNHSGVRA
TCPDCHVPHNWTDKIARKMQASKEVFAQVFGNYDEPGVFEARRIELAKHEWDRFSANKSLECKNCHNYDSMDFEQMSPTA
RIQMKQAAEKDQSCVDCHKGIAHKLPAGMDSIGGIVGDLEQMASNTDYSVGKELVSVRHLPIYFDAQGQTEAGLLNPAST
VKVLEDKGDYVEIEIDGWRKAKGFGRVIQEDFGKNIAVASLLKEASMDDKIVTTGEEKVDELTGLPWEKVAAKVWIKKES
MLNDINPVWEKSREAYKTNCSVCHTQPAEAHFDANTWPGMFDGMLAFVNLDTDSEALILKYLQKHSSDYAEGHH
>Mature_394_residues
MKSLIIKLWRTVTRPAVHISLGVLTVGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRDNVYQELQDTVHWKNHSGVRA
TCPDCHVPHNWTDKIARKMQASKEVFAQVFGNYDEPGVFEARRIELAKHEWDRFSANKSLECKNCHNYDSMDFEQMSPTA
RIQMKQAAEKDQSCVDCHKGIAHKLPAGMDSIGGIVGDLEQMASNTDYSVGKELVSVRHLPIYFDAQGQTEAGLLNPAST
VKVLEDKGDYVEIEIDGWRKAKGFGRVIQEDFGKNIAVASLLKEASMDDKIVTTGEEKVDELTGLPWEKVAAKVWIKKES
MLNDINPVWEKSREAYKTNCSVCHTQPAEAHFDANTWPGMFDGMLAFVNLDTDSEALILKYLQKHSSDYAEGHH

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=390, Percent_Identity=41.5384615384615, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1788530, Length=183, Percent_Identity=53.551912568306, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788181, Length=350, Percent_Identity=29.1428571428571, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44204; Mature: 44204

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLIIKLWRTVTRPAVHISLGVLTVGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRD
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
NVYQELQDTVHWKNHSGVRATCPDCHVPHNWTDKIARKMQASKEVFAQVFGNYDEPGVFE
HHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ARRIELAKHEWDRFSANKSLECKNCHNYDSMDFEQMSPTARIQMKQAAEKDQSCVDCHKG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IAHKLPAGMDSIGGIVGDLEQMASNTDYSVGKELVSVRHLPIYFDAQGQTEAGLLNPAST
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHH
VKVLEDKGDYVEIEIDGWRKAKGFGRVIQEDFGKNIAVASLLKEASMDDKIVTTGEEKVD
HHHEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCHHHHH
ELTGLPWEKVAAKVWIKKESMLNDINPVWEKSREAYKTNCSVCHTQPAEAHFDANTWPGM
HHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCH
FDGMLAFVNLDTDSEALILKYLQKHSSDYAEGHH
HHCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSLIIKLWRTVTRPAVHISLGVLTVGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRD
CHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
NVYQELQDTVHWKNHSGVRATCPDCHVPHNWTDKIARKMQASKEVFAQVFGNYDEPGVFE
HHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ARRIELAKHEWDRFSANKSLECKNCHNYDSMDFEQMSPTARIQMKQAAEKDQSCVDCHKG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IAHKLPAGMDSIGGIVGDLEQMASNTDYSVGKELVSVRHLPIYFDAQGQTEAGLLNPAST
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHH
VKVLEDKGDYVEIEIDGWRKAKGFGRVIQEDFGKNIAVASLLKEASMDDKIVTTGEEKVD
HHHEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCHHHHH
ELTGLPWEKVAAKVWIKKESMLNDINPVWEKSREAYKTNCSVCHTQPAEAHFDANTWPGM
HHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCH
FDGMLAFVNLDTDSEALILKYLQKHSSDYAEGHH
HHCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]