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The map label for this gene is cysS

Identifier: 37679546

GI number: 37679546

Start: 1386491

End: 1388020

Strand: Direct

Name: cysS

Synonym: VV1362

Alternate gene names: 37679546

Gene position: 1386491-1388020 (Clockwise)

Preceding gene: 37679541

Following gene: 37679547

Centisome position: 41.33

GC content: 46.54

Gene sequence:

>1530_bases
ATGCAAAACGAAGGACTAAGCAAATTACGCTTTTGTGTTGGAAGTTTAGTCGATTATCGTTTTTCAGCGGAATTGTTATT
ACCTAAAAACAATGTAGTTGGTATACTGCCGATTCATTTTAGTTCAATCAATATACAGATAGAGATCATGTTGAAGATAT
ATAACACACTGACAAGACAGAAAGAGGAATTCAAACCAATCACAGCCGGTAAAGTCGGTATGTATGTCTGTGGAGTTACC
ATTTACGATCTCTGTCACATCGGTCATGGCCGTACATTTGTCTCTTTTGACGTCGTATCTCGTTACTTGCGCTATTTAGG
TTACGATCTGACGTTTGTGCGCAACATTACCGATATCGATGACAAAATCATCAAACGTGCGGCGGAAAACGGTGAAACCT
GTGATTCATTGACCGAACGTTTGATCGGTGAAATGCACGCTGACTTCGATGCGCTAAACATGAAGCGCCCAGATGTGGAA
CCGCGCGCAACGCAATACATTCAAGAAATCATTGAGTTAGTTGAAAGACTGATTGAACGTGGTTTTGCGTATGTCGCCGA
CAACGGTGATGTGATGTTTGAAGTCAATAAATTTGACGAATACGGTAAGCTTTCTAAGCAAGACCTTGACCAGCTTCAAG
CGGGCGCGCGCGTCGATGTAGAAACAGCAAAACGCTGTCCTCTGGATTTCGTGTTGTGGAAAATGTCCAAGCCGGGTGAG
CCTACATGGGAATCCCCATGGGGGCCAGGTCGTCCTGGTTGGCACATCGAATGTTCGGCAATGAACTCGTCCATTCTTGG
TAATCATTTTGATATTCACGGCGGTGGCTCTGATCTTCAGTTCCCTCACCACGAAAACGAAATTGCTCAGTCTTGCTGTG
CCCATGACACTCAGTATGTGAATACTTGGATGCACAGCGGTATGGTGATGGTCGACAAAGAGAAGATGTCTAAGTCTCTA
GGTAACTTCTTCACTATTCGCGATGTGTTAGGTCACTATGATGCGGAAACCGTACGTTACTTCCTAATGTCAGGTCACTA
CCGCAGTCAGCTTAACTACAGCGAAGAAAATCTCAACCAAGCTCGCGCGTCACTAGAGCGCCTATACACTTCTCTGCGTG
GTTTGGATTTCTCGGCTGCGCCAGCAGGTGGTGAAGAGTATGTGTCACGCTTTACCGCAGCAATGAACGACGATTTCAAC
ACGCCGGAAGCCTATTCCGTGTTGTTTGATATGGCGCGTGAGATCAACCGATTGAAAACGGAAGATCTAGCCAACGCCAG
TGCTTTAGGTGCCTTGATGCGTGAGCTTGCTGACGTGATCGGCATTCTTCATCAAGATCCAGAAGCGTTTTTGAAAGGTG
ACGCGGGCAATGATGATGAAGTGGCAGAAATTGAAGCGTTGATCAAACTGCGTAACGATTCTCGTGCGGCGAAAGATTGG
GCAAACGCGGATATGGCGCGCGATAAGCTGAACGAGATGGGCATCGTACTTGAAGATGGCCCTGACGGAACAACGTGGCG
TCGCAAGTAA

Upstream 100 bases:

>100_bases
CTCAATCTTGATGTCACCAAAATTTGTGTGAAGGGTGATCATGCTGTTTTCCTTTGTGCTGTTTTGTTTAAAGTCAGAAT
TCTAGCCTAAGTTCAGGCTC

Downstream 100 bases:

>100_bases
TTGCATCTTTTTAAAGGGCTGTTGATTCAGCCCTTTTCTTTATATTTTTTCATTTTCCAATTTTACTTAGGTAGTGCTCT
GTGGCTCAGATGTATTTCTA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MQNEGLSKLRFCVGSLVDYRFSAELLLPKNNVVGILPIHFSSINIQIEIMLKIYNTLTRQKEEFKPITAGKVGMYVCGVT
IYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVE
PRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLDFVLWKMSKPGE
PTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYVNTWMHSGMVMVDKEKMSKSL
GNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFN
TPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPEAFLKGDAGNDDEVAEIEALIKLRNDSRAAKDW
ANADMARDKLNEMGIVLEDGPDGTTWRRK

Sequences:

>Translated_509_residues
MQNEGLSKLRFCVGSLVDYRFSAELLLPKNNVVGILPIHFSSINIQIEIMLKIYNTLTRQKEEFKPITAGKVGMYVCGVT
IYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVE
PRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLDFVLWKMSKPGE
PTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYVNTWMHSGMVMVDKEKMSKSL
GNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFN
TPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPEAFLKGDAGNDDEVAEIEALIKLRNDSRAAKDW
ANADMARDKLNEMGIVLEDGPDGTTWRRK
>Mature_509_residues
MQNEGLSKLRFCVGSLVDYRFSAELLLPKNNVVGILPIHFSSINIQIEIMLKIYNTLTRQKEEFKPITAGKVGMYVCGVT
IYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVE
PRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLDFVLWKMSKPGE
PTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYVNTWMHSGMVMVDKEKMSKSL
GNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFN
TPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPEAFLKGDAGNDDEVAEIEALIKLRNDSRAAKDW
ANADMARDKLNEMGIVLEDGPDGTTWRRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=497, Percent_Identity=34.20523138833, Blast_Score=256, Evalue=4e-68,
Organism=Homo sapiens, GI62240992, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI10835051, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI21269877, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI303304987, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=76.7895878524946, Blast_Score=724, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509795, Length=247, Percent_Identity=40.8906882591093, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17509797, Length=247, Percent_Identity=40.8906882591093, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324082, Length=378, Percent_Identity=33.0687830687831, Blast_Score=206, Evalue=8e-54,
Organism=Drosophila melanogaster, GI19922218, Length=499, Percent_Identity=35.2705410821643, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI19922364, Length=232, Percent_Identity=43.5344827586207, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 57583; Mature: 57583

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNEGLSKLRFCVGSLVDYRFSAELLLPKNNVVGILPIHFSSINIQIEIMLKIYNTLTRQ
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHH
KEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDID
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHHHHCCHHHH
DKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQEIIELVERLIER
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLDFVLWKMSKPGE
CCEEEECCCCEEEEECCCCHHCCCCHHHHHHHHCCCCCCHHHHHHCCHHHEEEECCCCCC
PTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYV
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCHHHH
NTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQ
HHHHHCCEEEEEHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCHHHHHH
ARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLFDMAREINRLKT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EDLANASALGALMRELADVIGILHQDPEAFLKGDAGNDDEVAEIEALIKLRNDSRAAKDW
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ANADMARDKLNEMGIVLEDGPDGTTWRRK
HHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MQNEGLSKLRFCVGSLVDYRFSAELLLPKNNVVGILPIHFSSINIQIEIMLKIYNTLTRQ
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHH
KEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDID
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHHHHCCHHHH
DKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQEIIELVERLIER
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLDFVLWKMSKPGE
CCEEEECCCCEEEEECCCCHHCCCCHHHHHHHHCCCCCCHHHHHHCCHHHEEEECCCCCC
PTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYV
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCHHHH
NTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQ
HHHHHCCEEEEEHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCCCHHHHHH
ARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLFDMAREINRLKT
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
EDLANASALGALMRELADVIGILHQDPEAFLKGDAGNDDEVAEIEALIKLRNDSRAAKDW
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ANADMARDKLNEMGIVLEDGPDGTTWRRK
HHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA