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The map label for this gene is tdk [H]

Identifier: 37679547

GI number: 37679547

Start: 1388101

End: 1388679

Strand: Direct

Name: tdk [H]

Synonym: VV1363

Alternate gene names: 37679547

Gene position: 1388101-1388679 (Clockwise)

Preceding gene: 37679546

Following gene: 37679551

Centisome position: 41.38

GC content: 44.73

Gene sequence:

>579_bases
GTGGCTCAGATGTATTTCTATTACTCAGCGATGAACGCGGGTAAATCAACGACTCTTCTTCAGTCTTCTTTCAACTATCA
AGAGCGTGGTATGACGCCCGTTATTTTTACTGCAGCTTTAGATGATCGCTATGGTATTGGTAAAGTCAGCTCACGAATTG
GCTTACAAGCTGAAGCGCAATTGTTTAAAGCAGACACCAATCTCTACCAAGAGATCGCTGCTCTGAATGAAGTGGAGAAA
CGCCATTGTATTTTGGTGGATGAGTGCCAATTCTTATCGAAAGAGCAAGTGTATCAGTTAACGGAAGTGGTCGATAAGCT
GCACATTCCTGTATTGTGTTACGGACTTCGTACGGATTTTCTTGGTGAGCTGTTTGAAGGCAGCAAATACCTCCTTTCTT
GGGCTGATAAATTGGTCGAGCTAAAAACCATTTGTCATTGTGGACGCAAAGCCAACATGGTTATCCGCACCGACGAGCAT
GGCAACGCGATTAAAGAAGGCGACCAAGTGGCGATTGGGGGGAACGATCGTTACGTGTCAGTCTGTCGTCAACACTACAA
AGAAGCGTTGGGTAAATAA

Upstream 100 bases:

>100_bases
CAACGTGGCGTCGCAAGTAATTGCATCTTTTTAAAGGGCTGTTGATTCAGCCCTTTTCTTTATATTTTTTCATTTTCCAA
TTTTACTTAGGTAGTGCTCT

Downstream 100 bases:

>100_bases
CGGGGTCTTTGAGTACCCCTACCGACAAGAATGCAATGAAGCCACTCACATCATGTGCAGTGGCTTTTTTTCGTTGGTTA
CTGCATTAAACGTGTGACTG

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQAEAQLFKADTNLYQEIAALNEVEK
RHCILVDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEH
GNAIKEGDQVAIGGNDRYVSVCRQHYKEALGK

Sequences:

>Translated_192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQAEAQLFKADTNLYQEIAALNEVEK
RHCILVDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEH
GNAIKEGDQVAIGGNDRYVSVCRQHYKEALGK
>Mature_191_residues
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQAEAQLFKADTNLYQEIAALNEVEKR
HCILVDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHG
NAIKEGDQVAIGGNDRYVSVCRQHYKEALGK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=70.5263157894737, Blast_Score=291, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21752; Mature: 21621

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQAEAQ
CCEEEEEEEECCCCCCHHHHHHCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHCCHHHHH
LFKADTNLYQEIAALNEVEKRHCILVDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDF
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCHHHHHHHHHHHHHHCCCHHEEHHHHHH
LGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHGNAIKEGDQVAIGGNDRYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHH
VCRQHYKEALGK
HHHHHHHHHHCC
>Mature Secondary Structure 
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMTPVIFTAALDDRYGIGKVSSRIGLQAEAQ
CEEEEEEEECCCCCCHHHHHHCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHCCHHHHH
LFKADTNLYQEIAALNEVEKRHCILVDECQFLSKEQVYQLTEVVDKLHIPVLCYGLRTDF
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCHHHHHHHHHHHHHHCCCHHEEHHHHHH
LGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHGNAIKEGDQVAIGGNDRYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHH
VCRQHYKEALGK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]