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The map label for this gene is fabD [H]

Identifier: 37679458

GI number: 37679458

Start: 1294920

End: 1295843

Strand: Direct

Name: fabD [H]

Synonym: VV1274

Alternate gene names: 37679458

Gene position: 1294920-1295843 (Clockwise)

Preceding gene: 37679457

Following gene: 37679459

Centisome position: 38.6

GC content: 49.13

Gene sequence:

>924_bases
ATGAGCAAGTTTGCTATCGTATTTCCAGGTCAAGGTTCTCAAGCAGTTGGTATGCTGGCAGATCTTGGCGAACAGTATGA
AATCGTTAAACAAACATTTGCACAAGCGTCAGAAGCGCTTGGCTACGATTTATGGGCACTGGTACAAAACGGTCCTGCGG
AAGATTTGAATCAGACGTTCCGCACTCAACCGGCATTGCTGGCTTCGTCGGTAGCGATCTGGCGAGTGTGGCAAGAATTA
GGTCTTGCTCAACCAGAAAACTTGGCAGGCCATAGCTTGGGTGAGTACTCAGCATTAGTGTGTGCTGGCGTGATTGATTT
CCAAGAAGCGATCAAACTTGTCGAGCTTCGTGGTCAACTTATGCAAGAAGCCGTACCAGCAGGGACTGGCGCGATGTACG
CGATCATCGGCCTAGATGATGAAGCGATTGCCAAAGCTTGTGAAGAAGCAGCGCAAGGCGAGGTGGTCTCTCCAGTGAAC
TTCAACTCTCCTGGCCAAGTGGTGATTGCAGGCAGCAAAGACGCAGTAGAGCGTGCGGGTGCACTGTGTAAAGAAGCGGG
CGCTAAACGTGCTCTTCCTCTTCCAGTTTCTGTGCCTTCACACTGTGCACTAATGAAACCAGCAGCAGAGAAACTTGCGG
TTGCACTGGAATCTATCGAATTCAAAGCCCCACAGCTGCCAGTGATCAACAACGTGGATGTGGTTGCAGAAACCGACCCA
GCGAGAATCAAAGATGCCCTAGTTCGTCAACTGTACAGCCCAGTTCGTTGGACTGAAAGTGTGGAACTAATGAGTTCACA
GGGTGTCGAAAAATTGCTTGAAATGGGCCCTGGTAAAGTATTGACAGGTTTGACAAAACGTATTGTCAAATCACTAGAAG
CAGCGGTAGTAAACGATGTTGCATCGCTTGACGCTGTAAAGTAA

Upstream 100 bases:

>100_bases
GGGGTTCGGCATTAGTTCGCTTTTAATTAAGAATTCTAATTTTGCTGTTGCTCGTGAGTAGTAACAGCATTTTATTTAGC
TTCGGTTAAGGAAAATTACT

Downstream 100 bases:

>100_bases
TAGGGAATAAAAATGACTGACTTATTAAACCTAAGCGGTAAAGTTGCGTTAGTAACGGGCGCGAGCCGTGGTATCGGTCG
CGCAATCGCAGAAACTCTGG

Product: acyl carrier protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSKFAIVFPGQGSQAVGMLADLGEQYEIVKQTFAQASEALGYDLWALVQNGPAEDLNQTFRTQPALLASSVAIWRVWQEL
GLAQPENLAGHSLGEYSALVCAGVIDFQEAIKLVELRGQLMQEAVPAGTGAMYAIIGLDDEAIAKACEEAAQGEVVSPVN
FNSPGQVVIAGSKDAVERAGALCKEAGAKRALPLPVSVPSHCALMKPAAEKLAVALESIEFKAPQLPVINNVDVVAETDP
ARIKDALVRQLYSPVRWTESVELMSSQGVEKLLEMGPGKVLTGLTKRIVKSLEAAVVNDVASLDAVK

Sequences:

>Translated_307_residues
MSKFAIVFPGQGSQAVGMLADLGEQYEIVKQTFAQASEALGYDLWALVQNGPAEDLNQTFRTQPALLASSVAIWRVWQEL
GLAQPENLAGHSLGEYSALVCAGVIDFQEAIKLVELRGQLMQEAVPAGTGAMYAIIGLDDEAIAKACEEAAQGEVVSPVN
FNSPGQVVIAGSKDAVERAGALCKEAGAKRALPLPVSVPSHCALMKPAAEKLAVALESIEFKAPQLPVINNVDVVAETDP
ARIKDALVRQLYSPVRWTESVELMSSQGVEKLLEMGPGKVLTGLTKRIVKSLEAAVVNDVASLDAVK
>Mature_306_residues
SKFAIVFPGQGSQAVGMLADLGEQYEIVKQTFAQASEALGYDLWALVQNGPAEDLNQTFRTQPALLASSVAIWRVWQELG
LAQPENLAGHSLGEYSALVCAGVIDFQEAIKLVELRGQLMQEAVPAGTGAMYAIIGLDDEAIAKACEEAAQGEVVSPVNF
NSPGQVVIAGSKDAVERAGALCKEAGAKRALPLPVSVPSHCALMKPAAEKLAVALESIEFKAPQLPVINNVDVVAETDPA
RIKDALVRQLYSPVRWTESVELMSSQGVEKLLEMGPGKVLTGLTKRIVKSLEAAVVNDVASLDAVK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=296, Percent_Identity=34.7972972972973, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=42.9906542056075, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787334, Length=305, Percent_Identity=72.1311475409836, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=30.6122448979592, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=31.4569536423841, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=33.2225913621262, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32504; Mature: 32373

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFAIVFPGQGSQAVGMLADLGEQYEIVKQTFAQASEALGYDLWALVQNGPAEDLNQTF
CCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHH
RTQPALLASSVAIWRVWQELGLAQPENLAGHSLGEYSALVCAGVIDFQEAIKLVELRGQL
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPAGTGAMYAIIGLDDEAIAKACEEAAQGEVVSPVNFNSPGQVVIAGSKDAVERAG
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKEAGAKRALPLPVSVPSHCALMKPAAEKLAVALESIEFKAPQLPVINNVDVVAETDP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCH
ARIKDALVRQLYSPVRWTESVELMSSQGVEKLLEMGPGKVLTGLTKRIVKSLEAAVVNDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLDAVK
HHHCCCC
>Mature Secondary Structure 
SKFAIVFPGQGSQAVGMLADLGEQYEIVKQTFAQASEALGYDLWALVQNGPAEDLNQTF
CCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHH
RTQPALLASSVAIWRVWQELGLAQPENLAGHSLGEYSALVCAGVIDFQEAIKLVELRGQL
HCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPAGTGAMYAIIGLDDEAIAKACEEAAQGEVVSPVNFNSPGQVVIAGSKDAVERAG
HHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKEAGAKRALPLPVSVPSHCALMKPAAEKLAVALESIEFKAPQLPVINNVDVVAETDP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCH
ARIKDALVRQLYSPVRWTESVELMSSQGVEKLLEMGPGKVLTGLTKRIVKSLEAAVVNDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLDAVK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]