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The map label for this gene is fabH1 [H]

Identifier: 37679457

GI number: 37679457

Start: 1293895

End: 1294845

Strand: Direct

Name: fabH1 [H]

Synonym: VV1273

Alternate gene names: 37679457

Gene position: 1293895-1294845 (Clockwise)

Preceding gene: 161486634

Following gene: 37679458

Centisome position: 38.57

GC content: 47.42

Gene sequence:

>951_bases
ATGTATAGCAAAATTTTAGGTACTGGCAGCTACCTGCCATCTCAGATCCGCACCAATGCCGATCTAGAGAAAATGGTAGA
GACAAGTGATGAGTGGATTGTTGCCCGAACTGGTATTAAAGAGCGTCGTATTGCTGCTGAAAATGAAACGGTAGCTGATA
TGGGTTTTTATGCGGCTCAAAACGCGATAGAGATGGCAGGTATCGACAAAAATGATATTGACCTGATCATCGTCGCGACG
ACAAGTGGAAGCCATACTTTTCCTTCATCTGCATGTCAGGTGCAGGCAAAGCTTGGCATCAAAGGTTGTCCTGCATTCGA
TTTAGCTGCTGCGTGCTCTGGCTTTGTCTACGCACTTTCTATTGCTGATCAACATATTAAAACGGGTATGTGTAAAAACG
TACTGGTTATTGGCTCCGATACTTTATCGAAAACTTGTGATCCAACGGACCGCTCGACCATTATCTTATTCGGTGATGGT
GCCGGTGCTGTGGTTGTTGGAGCAAGCGAAGAGCCGGGTATTCTGTCTACTCACATCTACGCGGATGGTGAGTTTGGCGA
TCTTCTTAGCTTAGAAGTACCTGAGCGCGGCAAAGATGCCGACAAATGGTTACACATGGCGGGTAACGAAGTATTCAAAG
TAGCGGTGACTCAGTTATCGAAACTGGTGAAAGATACTCTAGAAGCGAACGGCATGCATAAATCTGAGTTGGATTGGTTA
GTTCCACATCAGGCGAACTACCGGATCATCTCAGCGACGGCGAAAAAACTGTCTATGTCGCTCGATCAAGTGGTGATTAC
CCTTGATCGTCATGGCAATACCTCTGCGGCAACCGTACCGACGGCATTAGATGAGGCCGTGCGTGATGGGCGTATTCAGC
GTGGTCAGACGCTACTACTAGAAGCCTTTGGTGGCGGTTTCACCTGGGGTTCGGCATTAGTTCGCTTTTAA

Upstream 100 bases:

>100_bases
ATGCGATTGGTGAGGCGGTACACGAGGTCAAACGACAAGTACCAAGCCGTATAAGCGATCGTTTGGAAGCGGTTTTACTC
GAGAGGCATTATTAGTCTTC

Downstream 100 bases:

>100_bases
TTAAGAATTCTAATTTTGCTGTTGCTCGTGAGTAGTAACAGCATTTTATTTAGCTTCGGTTAAGGAAAATTACTATGAGC
AAGTTTGCTATCGTATTTCC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYSKILGTGSYLPSQIRTNADLEKMVETSDEWIVARTGIKERRIAAENETVADMGFYAAQNAIEMAGIDKNDIDLIIVAT
TSGSHTFPSSACQVQAKLGIKGCPAFDLAAACSGFVYALSIADQHIKTGMCKNVLVIGSDTLSKTCDPTDRSTIILFGDG
AGAVVVGASEEPGILSTHIYADGEFGDLLSLEVPERGKDADKWLHMAGNEVFKVAVTQLSKLVKDTLEANGMHKSELDWL
VPHQANYRIISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLLEAFGGGFTWGSALVRF

Sequences:

>Translated_316_residues
MYSKILGTGSYLPSQIRTNADLEKMVETSDEWIVARTGIKERRIAAENETVADMGFYAAQNAIEMAGIDKNDIDLIIVAT
TSGSHTFPSSACQVQAKLGIKGCPAFDLAAACSGFVYALSIADQHIKTGMCKNVLVIGSDTLSKTCDPTDRSTIILFGDG
AGAVVVGASEEPGILSTHIYADGEFGDLLSLEVPERGKDADKWLHMAGNEVFKVAVTQLSKLVKDTLEANGMHKSELDWL
VPHQANYRIISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLLEAFGGGFTWGSALVRF
>Mature_316_residues
MYSKILGTGSYLPSQIRTNADLEKMVETSDEWIVARTGIKERRIAAENETVADMGFYAAQNAIEMAGIDKNDIDLIIVAT
TSGSHTFPSSACQVQAKLGIKGCPAFDLAAACSGFVYALSIADQHIKTGMCKNVLVIGSDTLSKTCDPTDRSTIILFGDG
AGAVVVGASEEPGILSTHIYADGEFGDLLSLEVPERGKDADKWLHMAGNEVFKVAVTQLSKLVKDTLEANGMHKSELDWL
VPHQANYRIISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLLEAFGGGFTWGSALVRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=71.9242902208202, Blast_Score=483, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 33857; Mature: 33857

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSKILGTGSYLPSQIRTNADLEKMVETSDEWIVARTGIKERRIAAENETVADMGFYAAQ
CCCCEECCCCCCCHHHCCCCCHHHHHCCCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHC
NAIEMAGIDKNDIDLIIVATTSGSHTFPSSACQVQAKLGIKGCPAFDLAAACSGFVYALS
CHHEECCCCCCCCEEEEEEECCCCCCCCCHHEEEEEECCCCCCCCHHHHHHHCCCEEEEE
IADQHIKTGMCKNVLVIGSDTLSKTCDPTDRSTIILFGDGAGAVVVGASEEPGILSTHIY
HHHHHHHHCCCCCEEEECCCHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGEFGDLLSLEVPERGKDADKWLHMAGNEVFKVAVTQLSKLVKDTLEANGMHKSELDWL
ECCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VPHQANYRIISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLL
CCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVRF
EECCCCCCHHHHHHCC
>Mature Secondary Structure
MYSKILGTGSYLPSQIRTNADLEKMVETSDEWIVARTGIKERRIAAENETVADMGFYAAQ
CCCCEECCCCCCCHHHCCCCCHHHHHCCCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHC
NAIEMAGIDKNDIDLIIVATTSGSHTFPSSACQVQAKLGIKGCPAFDLAAACSGFVYALS
CHHEECCCCCCCCEEEEEEECCCCCCCCCHHEEEEEECCCCCCCCHHHHHHHCCCEEEEE
IADQHIKTGMCKNVLVIGSDTLSKTCDPTDRSTIILFGDGAGAVVVGASEEPGILSTHIY
HHHHHHHHCCCCCEEEECCCHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGEFGDLLSLEVPERGKDADKWLHMAGNEVFKVAVTQLSKLVKDTLEANGMHKSELDWL
ECCCCCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
VPHQANYRIISATAKKLSMSLDQVVITLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLL
CCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVRF
EECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]