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The map label for this gene is luxO [H]

Identifier: 37679379

GI number: 37679379

Start: 1211703

End: 1213103

Strand: Direct

Name: luxO [H]

Synonym: VV1195

Alternate gene names: 37679379

Gene position: 1211703-1213103 (Clockwise)

Preceding gene: 37679377

Following gene: 37679380

Centisome position: 36.12

GC content: 47.61

Gene sequence:

>1401_bases
ATGCAACAAATAACGACAACGAAACAGCGCTACTTGCTGATGGTAGAAGACACCGCTTCTGTCGCAGCCCTCTATCGCTC
CTATCTCATGCCATTGGGTATCGATATCAATATCGTGGGTACTGGGCGCGACGCGATAGACAGTTTAAAACATCGCATTC
CAGATCTTATTCTGCTGGATTTACGTCTACCGGACATGACGGGAATGGACGTATTGCATGCAGTGAAAGCAAGTCACCCT
GATGTTCCTATCATTTTCATGACCGCACACGGCTCGATCGATACTGCCGTTGAAGCAATGCGACATGGTTCTCAGGATTT
TCTTATCAAGCCATGCGAAGCGGATCGCTTGAGGGTCACGGTAAACAACGCTATCCGCAAAGCGAGTAAATTGAAGAATG
ATGCGGACAGTGCAGGCAGCCAAAATTATCAAGGCTTTATCGGCAGTAGCCAAAAAATGCAGCAGGTTTATCGCACCATT
GACTCCGCGGCGAGCAGTAAAGCAAGCATCTTTATCACAGGTGAAAGTGGTACAGGTAAAGAGGTGTGCGCAGAAGCCAT
TCATGCGGCCAGTCGACGTGGAGACAAGCCATTTATTGCGATTAACTGTGCTGCGATTCCCAAAGATTTGATTGAAAGCG
AGCTATTTGGTCATGTCAAAGGTGCGTTTACCGGCGCTGCGACCGATCGCCAAGGGGCGGCAGAGCTCGCTGATGGAGGC
ACACTTTTCCTGGATGAGCTGTGTGAAATGGACTTGGATCTGCAAACAAAATTGCTGCGTTTTATCCAAACGGGTACTTT
CCAAAAAGTAGGCTCTTCAAAAATGAAGAGTGTTGACGTGCGTTTTGTGTGCGCGACAAACCGAGACCCCTGGAAAGAGG
TACAAGAAGGGCGCTTTCGTGAAGATTTGTACTACCGACTTTATGTGATTCCACTGCACTTGCCACCACTTCGTGAACGT
GGAGAGGATGTCATCGAGATCGCTTACTCGTTACTGGGTTACATGTCACACGAGGAAGGGAAAAACTTTGTTCGTTTCTC
TCAACCTGTGATAGATAGATTTAACGAATATGAGTGGCCAGGTAATGTGCGTCAGTTACAAAATGTGCTGCGTAATGTGG
TGGTGCTTAACAACGGTAAAGAGATTACCATGGAGATGCTGCCGCCTCCTTTGAACCAGCCCTTTGAACGCAAAGAAAGT
GTGCAGCCTGATCTGAGTGAGTTGATTTCCGTCAGGGATATTTGTCCATTGTGGTTGACAGAGAAACTGGCGATTGAACA
AGCGATCAAAGCGTGTGATGGTAACATTCCGAGAGCCGCCGGCTATCTGGATGTCAGCCCGTCAACGATTTATCGCAAGT
TACAGGCGTGGAACGAAAAAGAAGAAAAACAGAAAGCATAA

Upstream 100 bases:

>100_bases
GATTATTTACCGTTAAAAGTGAATATTTGCCATTGTTATTTGCAAAATGCATCGCGCAATGCGATTATTATCCAAAACAC
AAATGATAATTGGCTAGATT

Downstream 100 bases:

>100_bases
TGGAATTACTAAATCAGAAGAAAATTGCCTCGTTGACAGAGGAAATAGGCGCCGACAATGTCCCCGTGTTGTTGGAGATA
TTTTTGAGCGAGCTTGAGAG

Product: luxO repressor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQQITTTKQRYLLMVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLDLRLPDMTGMDVLHAVKASHP
DVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTI
DSAASSKASIFITGESGTGKEVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGG
TLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRER
GEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWPGNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKES
VQPDLSELISVRDICPLWLTEKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA

Sequences:

>Translated_466_residues
MQQITTTKQRYLLMVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLDLRLPDMTGMDVLHAVKASHP
DVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTI
DSAASSKASIFITGESGTGKEVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGG
TLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRER
GEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWPGNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKES
VQPDLSELISVRDICPLWLTEKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA
>Mature_466_residues
MQQITTTKQRYLLMVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLDLRLPDMTGMDVLHAVKASHP
DVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTI
DSAASSKASIFITGESGTGKEVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGG
TLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRER
GEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWPGNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKES
VQPDLSELISVRDICPLWLTEKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA

Specific function: Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=38.963963963964, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=39.4678492239468, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1790299, Length=393, Percent_Identity=42.7480916030534, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1788905, Length=448, Percent_Identity=37.5, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI87082117, Length=365, Percent_Identity=38.3561643835616, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=40.4833836858006, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=259, Percent_Identity=46.7181467181467, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789087, Length=301, Percent_Identity=40.8637873754153, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786524, Length=324, Percent_Identity=38.2716049382716, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1787583, Length=264, Percent_Identity=39.7727272727273, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081872, Length=254, Percent_Identity=40.1574803149606, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789828, Length=284, Percent_Identity=32.7464788732394, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081858, Length=393, Percent_Identity=25.9541984732824, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786838, Length=133, Percent_Identity=33.0827067669173, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52121; Mature: 52121

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQITTTKQRYLLMVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLD
CCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEE
LRLPDMTGMDVLHAVKASHPDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVT
EECCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCEEEE
VNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTIDSAASSKASIFITGESGTGK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
EVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGG
HHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
TLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFR
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCHHCEEEEEEEEECCCCHHHHHHCCCCH
EDLYYRLYVIPLHLPPLRERGEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWP
HCEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHCCCCCC
GNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKESVQPDLSELISVRDICPLWLT
CCHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHH
EKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA
HHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MQQITTTKQRYLLMVEDTASVAALYRSYLMPLGIDINIVGTGRDAIDSLKHRIPDLILLD
CCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCEEEEE
LRLPDMTGMDVLHAVKASHPDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVT
EECCCCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCEEEE
VNNAIRKASKLKNDADSAGSQNYQGFIGSSQKMQQVYRTIDSAASSKASIFITGESGTGK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
EVCAEAIHAASRRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATDRQGAAELADGG
HHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
TLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFR
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHCCCHHCEEEEEEEEECCCCHHHHHHCCCCH
EDLYYRLYVIPLHLPPLRERGEDVIEIAYSLLGYMSHEEGKNFVRFSQPVIDRFNEYEWP
HCEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHCCCCCC
GNVRQLQNVLRNVVVLNNGKEITMEMLPPPLNQPFERKESVQPDLSELISVRDICPLWLT
CCHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHH
EKLAIEQAIKACDGNIPRAAGYLDVSPSTIYRKLQAWNEKEEKQKA
HHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA