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The map label for this gene is ppiD [H]

Identifier: 37679292

GI number: 37679292

Start: 1115567

End: 1117444

Strand: Direct

Name: ppiD [H]

Synonym: VV1108

Alternate gene names: 37679292

Gene position: 1115567-1117444 (Clockwise)

Preceding gene: 37679291

Following gene: 37679293

Centisome position: 33.26

GC content: 45.69

Gene sequence:

>1878_bases
GTGGAGAGCAGTTTAGTTATGATGGATCGATTGCGCGAAGGCGTGAATAGCATCGCGGTTAAAATTATCCTAGGATTGAT
CATCCTATCGTTTGTCTTTGCAGGTGTCGGCAGTTACCTCGTGAGTGGTAGTAGTAACTCTGCAGCAAAAGTTGGCAATG
TCGAAATCGGTCGTGGTGAGTTTGAAATGGCTTACCAAAACGAGCGTAATCGTATGCAGTCGCAACTAGGAGATTACTTT
TCTCAACTCCTTGCTGACCCTGCTTACGTAGAGTCTTTCCGTAAATCGGTATTAGACCGCATGATTAATGACGTTTTGCT
TGATCAGCATGCAGAATCATTAGGTTTACGCATCAGTGATGCTCAAGTAAGAAGCATGATTCTAGCGATGCCAGAATTCC
AGCAAGACGGTAAATTCAACCAAGACGTCTACCAAGCGACCCTACGTCGCGCGGGCTACTCACCAGATTCTTTTGCAGAG
TACATGCGTCGTGAACTGATTCGTTCTCAATTGCTTGATGCACTACAAACCAGCGAATTTACCCTACCAGGTGAAGTGGA
TGCAGAAGGTAAACTGTTTACTCAAACACGTGATGTTCGCACGGTGACGCTAAATATTCGCGACTTTGCAGATAAAGTGA
CGCTGACAGAAGAAGATATCCAAAAGTACTACGATGAAAACAAATCACGCTTTACTCGCCCTGAGCAGGTGAAGGTGTCT
TACATCGAGTTAGCGGCGGATTCACTCAAGCAGCAAATCACCATTTCTGATGACGAAGTGAAACAGTACTATCAAGAGCA
CCTTGATAAGTATTCCTCTGAGGAGAAGCGTCGAGTGGCTCATATCCTCATTGAGGGGGATGACCAAGCTAAAGCACAAG
CAATTTTAGACGAATTGAACGCTGGTGCGGATTTCGCGGCACTAGCTCAAGACAAATCAGACGATTTTGGCAGTGCTGAT
AACGGCGGTGAACTGGGTTGGATTGAACGTGGTGTGATGGACCCAGCGTTTGAAGAAGCGGCGTTTGCGCTAAAAAATGT
GGGTGATGTCACTGGCTTGGTGAAGTCTGACTTCGGCTACCACATCATCAAACTCGAAGAGCTAAAAGAACCGGTTGTGA
AGCCATTTAGCGACGTTGCTGCGCAAATCAAACAAGAAATGATCGACCAGAAAGCAGTCGACCAATTCTATGAGTTGCAA
AGTGAGCTAGAGAAAGTGGCATTCGAATACCCAGATTCTTTAGAAGAAGCATCAAAAGCGGTGGGTCAACAAGTGAAACA
CACTGACTTTATCTCTCAAGTTGATGCGCCTGAAATTCTTCGTACACCTGCGGTTACTCAAGCGATTACCAGTCCAGAAG
TTAAGTTGGATGGCCTGAACTCAGAAGCGATTGAAATTGCTCCTGAACACATCATCGTTGTTCGTGTTGATGATGCTCGT
GATGAGACGGTGCTACCTTTGACTGAGGTGCAAGACCAAGTAGCTGCAGAGCTTTCTCAAGTGAAAGGTGAGCAACAAGC
ACTTGAGCTGGGAACCGAAGTCGTGACGGCACTGAAAGCGGGTAACACAGCTATTTTACAAGAAAAAGGCTTATCGTTTG
GTGAGTTAGAGAAGATTGATCGTCGTTCTCCTTTAGCTCAGACCGTGTTTGCTATGGCAAAACCAGCAGCAGGTAATGCG
GTATACGGCCAAAGTAAAGATATGGAAGGCAATGTTGTTGTCGTGGCGCTTGAAAAAGTAGAAGAGAGCTTAGAGCCTGT
ACTAGCACAGCAAATTTCAGTGCAATTGCAACGTGTCTCTGCACAGCGTGACTTGAGTTCTATCGTCGCGATTCTTCGTG
CTAACACCGATATTGAATACTTTGTTGTGAGCAACTAA

Upstream 100 bases:

>100_bases
AAGCCGAACTTTTTTAAATTATGCGCATCCTACTGATGCGCATTTCTTTTTTCTGGTATTATCGCGTGATTACATTTCAA
GAGAAGCGTTGGCTTCGTGA

Downstream 100 bases:

>100_bases
TCGTTCGGTGTGCAACTGATATGTAACTAAAAACAGGTCGCTTTCGCGGCCTGTTTTATTTTTGTCTCTTGTCTGTTTTG
TGCTCTCGCTGGGTTAGGTA

Product: parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MESSLVMMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYF
SQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAE
YMRRELIRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVS
YIELAADSLKQQITISDDEVKQYYQEHLDKYSSEEKRRVAHILIEGDDQAKAQAILDELNAGADFAALAQDKSDDFGSAD
NGGELGWIERGVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQ
SELEKVAFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDAR
DETVLPLTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNA
VYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN

Sequences:

>Translated_625_residues
MESSLVMMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYF
SQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAE
YMRRELIRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVS
YIELAADSLKQQITISDDEVKQYYQEHLDKYSSEEKRRVAHILIEGDDQAKAQAILDELNAGADFAALAQDKSDDFGSAD
NGGELGWIERGVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQ
SELEKVAFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDAR
DETVLPLTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNA
VYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN
>Mature_625_residues
MESSLVMMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYF
SQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAE
YMRRELIRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVS
YIELAADSLKQQITISDDEVKQYYQEHLDKYSSEEKRRVAHILIEGDDQAKAQAILDELNAGADFAALAQDKSDDFGSAD
NGGELGWIERGVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQ
SELEKVAFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDAR
DETVLPLTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNA
VYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=625, Percent_Identity=38.88, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69382; Mature: 69382

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSLVMMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
FEMAYQNERNRMQSQLGDYFSQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECH
AQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRRELIRSQLLDALQTSEF
HHHHHHHHHCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVS
CCCCCCCCCCCEEEECCCEEEEEEEHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHH
YIELAADSLKQQITISDDEVKQYYQEHLDKYSSEEKRRVAHILIEGDDQAKAQAILDELN
HHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCHHHHHHHHHHHC
AGADFAALAQDKSDDFGSADNGGELGWIERGVMDPAFEEAAFALKNVGDVTGLVKSDFGY
CCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
HIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKVAFEYPDSLEEASKA
EEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDAR
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCEEECCCCCCCEEECCCEEEEEEECCCC
DETVLPLTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKID
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHH
RRSPLAQTVFAMAKPAAGNAVYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVS
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AQRDLSSIVAILRANTDIEYFVVSN
HHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MESSLVMMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCC
FEMAYQNERNRMQSQLGDYFSQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISD
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECH
AQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRRELIRSQLLDALQTSEF
HHHHHHHHHCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVS
CCCCCCCCCCCEEEECCCEEEEEEEHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHH
YIELAADSLKQQITISDDEVKQYYQEHLDKYSSEEKRRVAHILIEGDDQAKAQAILDELN
HHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCHHHHHHHHHHHC
AGADFAALAQDKSDDFGSADNGGELGWIERGVMDPAFEEAAFALKNVGDVTGLVKSDFGY
CCCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
HIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKVAFEYPDSLEEASKA
EEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDAR
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCEEECCCCCCCEEECCCEEEEEEECCCC
DETVLPLTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKID
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHH
RRSPLAQTVFAMAKPAAGNAVYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVS
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AQRDLSSIVAILRANTDIEYFVVSN
HHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]