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The map label for this gene is purP [H]

Identifier: 37679037

GI number: 37679037

Start: 859196

End: 859825

Strand: Direct

Name: purP [H]

Synonym: VV0853

Alternate gene names: 37679037

Gene position: 859196-859825 (Clockwise)

Preceding gene: 37679035

Following gene: 37679038

Centisome position: 25.61

GC content: 48.57

Gene sequence:

>630_bases
ATGCTCGAAAGGCTATTTAAACTCAGCGAACATGGCACAAATGTGCGCACTGAGATCATTGCAGGTATTACTACCTTCTT
GACGATGGCTTACATCATTTTTGTTAACCCAGCGATTCTAGCTGATGCGGGAATGGACCGTGGTGCCGTGTTTGTTGCTA
CCTGTCTTGCCGCAGCAATTGGCTGTTTCATCATGGGTCTACTTGCCAACTACCCAATCGCACAGGCGCCAGGTATGGGC
TTAAATGCCTTCTTTACCTACGCGGTTGTTCTGGGAATGGGGTACACCTGGCAAGTCGCATTGGCGGCCGTATTTGTGTC
GGGTGTGCTTTTTATCCTGTTGAGCATCTTCAAAATTCGTGAGTGGATCATCAACTCGATTCCGCTCTCTTTGAGAACGG
GGATCTCAGCGGGTATCGGCTTGTTCCTTGCGTTCATCGCTCTGAAAAATGCAGGCATTGTTGTTGATAATCCTGCGACG
TTTGTTTCTCTTGGCGATATCACTTCTCTCGCACCAGCGTCTGGCGGCTTTTGGTTTCTTTTTGACTATTGCACTTGTTC
ACCGTGGTGTGAAAGGGGCAGTAATGATTGCGATCTTAGCTGTGACGGCACTTGGTTTGGTGTTTGGTGA

Upstream 100 bases:

>100_bases
AGAGTGAAAAATCTATCTGGAATTTGTTATTTGATAACTTTATAATCTGCAGCCAATCGATTACGCAACCGTTTACTTTT
TACCTTTACAGGATTCGATC

Downstream 100 bases:

>100_bases
TGTCCAATGGGCGGGTGTGATGTCAACCCCACCAAGTATTGCGCCTACGTTCATGCAACTGGACTTCTCTGCGGTATTTG
AAGTAGGCATGATTTCAGTG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLERLFKLSEHGTNVRTEIIAGITTFLTMAYIIFVNPAILADAGMDRGAVFVATCLAAAIGCFIMGLLANYPIAQAPGMG
LNAFFTYAVVLGMGYTWQVALAAVFVSGVLFILLSIFKIREWIINSIPLSLRTGISAGIGLFLAFIALKNAGIVVDNPAT
FVSLGDITSLAPASGGFWFLFDYCTCSPWCERGSNDCDLSCDGTWFGVW

Sequences:

>Translated_209_residues
MLERLFKLSEHGTNVRTEIIAGITTFLTMAYIIFVNPAILADAGMDRGAVFVATCLAAAIGCFIMGLLANYPIAQAPGMG
LNAFFTYAVVLGMGYTWQVALAAVFVSGVLFILLSIFKIREWIINSIPLSLRTGISAGIGLFLAFIALKNAGIVVDNPAT
FVSLGDITSLAPASGGFWFLFDYCTCSPWCERGSNDCDLSCDGTWFGVW
>Mature_209_residues
MLERLFKLSEHGTNVRTEIIAGITTFLTMAYIIFVNPAILADAGMDRGAVFVATCLAAAIGCFIMGLLANYPIAQAPGMG
LNAFFTYAVVLGMGYTWQVALAAVFVSGVLFILLSIFKIREWIINSIPLSLRTGISAGIGLFLAFIALKNAGIVVDNPAT
FVSLGDITSLAPASGGFWFLFDYCTCSPWCERGSNDCDLSCDGTWFGVW

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=169, Percent_Identity=60.9467455621302, Blast_Score=214, Evalue=2e-57,
Organism=Escherichia coli, GI87082309, Length=168, Percent_Identity=58.3333333333333, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1790499, Length=167, Percent_Identity=46.1077844311377, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI48994909, Length=170, Percent_Identity=44.1176470588235, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 22425; Mature: 22425

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLFKLSEHGTNVRTEIIAGITTFLTMAYIIFVNPAILADAGMDRGAVFVATCLAAAI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHH
GCFIMGLLANYPIAQAPGMGLNAFFTYAVVLGMGYTWQVALAAVFVSGVLFILLSIFKIR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPLSLRTGISAGIGLFLAFIALKNAGIVVDNPATFVSLGDITSLAPASGGFWFL
HHHHHCCCHHHHHCHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCHHHCCCCCCCEEEE
FDYCTCSPWCERGSNDCDLSCDGTWFGVW
EEHHCCCHHHHCCCCCCCEECCCCEEECC
>Mature Secondary Structure
MLERLFKLSEHGTNVRTEIIAGITTFLTMAYIIFVNPAILADAGMDRGAVFVATCLAAAI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHH
GCFIMGLLANYPIAQAPGMGLNAFFTYAVVLGMGYTWQVALAAVFVSGVLFILLSIFKIR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPLSLRTGISAGIGLFLAFIALKNAGIVVDNPATFVSLGDITSLAPASGGFWFL
HHHHHCCCHHHHHCHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCHHHCCCCCCCEEEE
FDYCTCSPWCERGSNDCDLSCDGTWFGVW
EEHHCCCHHHHCCCCCCCEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]