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The map label for this gene is hscB

Identifier: 37678942

GI number: 37678942

Start: 762764

End: 763279

Strand: Direct

Name: hscB

Synonym: VV0758

Alternate gene names: 37678942

Gene position: 762764-763279 (Clockwise)

Preceding gene: 37678941

Following gene: 37678943

Centisome position: 22.74

GC content: 45.74

Gene sequence:

>516_bases
ATGAATCACTTTGAATTGTTTGGGCTACCACCTCAGTTTTCTCTGGATGGTAGCCTTCTTTCTTCTCAGTTCCGAGAATT
GCAAAAACGCTTCCATCCGGACAATTTTGCGACCGCTTCTGAACGCGATCGTTTGTTAGCGGTACAAAAAGCGGCACAAA
TTAATGATGCTTACCAGGTGCTTAAGAATCCCATTTCTCGTGCGGAGTACCTTTTGTCGCAAAACGGTTTAGAAATCCGA
GGTGAGCAGCAAACCATGCAAGATCCCATGTTTCTGATGGAACAGATGGAATTGCGTGAAGAGTTGGAAGAGATCCCTCA
TGGCTCAGATGCTGAGAGTGCTTTGGCGGCGTTTGATGCCAGAGTGAGCAAAATGTACAAACAACATCTCGCATCAATTG
AGCAAGAGCTGAATGACGCTCAGTGGCCACAAGCCGCCGATCGCGTACGTAAGCTGAAATTTATTGCCAAACTAAAGAAT
GAAATAGAGCTAGTGGAAGAGAAACTCTTCGGCTAG

Upstream 100 bases:

>100_bases
GAAAAGTGAATGTGGTTGCGGTGAAAGCTTCAACGTCTAATGACTGAAATTCTGAGCCGTTACCGTCGGCTCAGAAGGTT
TATTCAAGGACCATAGATCA

Downstream 100 bases:

>100_bases
TTTGAAAAACAAGGATCCATCATGGCATTACTTCAAATTGCAGAACCGGGCCAAAGCTCGGCACCTCATGAGCACAAAAG
AGCAGCCGGTATCGATCTTG

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNHFELFGLPPQFSLDGSLLSSQFRELQKRFHPDNFATASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLSQNGLEIR
GEQQTMQDPMFLMEQMELREELEEIPHGSDAESALAAFDARVSKMYKQHLASIEQELNDAQWPQAADRVRKLKFIAKLKN
EIELVEEKLFG

Sequences:

>Translated_171_residues
MNHFELFGLPPQFSLDGSLLSSQFRELQKRFHPDNFATASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLSQNGLEIR
GEQQTMQDPMFLMEQMELREELEEIPHGSDAESALAAFDARVSKMYKQHLASIEQELNDAQWPQAADRVRKLKFIAKLKN
EIELVEEKLFG
>Mature_171_residues
MNHFELFGLPPQFSLDGSLLSSQFRELQKRFHPDNFATASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLSQNGLEIR
GEQQTMQDPMFLMEQMELREELEEIPHGSDAESALAAFDARVSKMYKQHLASIEQELNDAQWPQAADRVRKLKFIAKLKN
EIELVEEKLFG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=163, Percent_Identity=26.3803680981595, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=47.6470588235294, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17541320, Length=140, Percent_Identity=29.2857142857143, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161084223, Length=104, Percent_Identity=35.5769230769231, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19723; Mature: 19723

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFELFGLPPQFSLDGSLLSSQFRELQKRFHPDNFATASERDRLLAVQKAAQINDAYQV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKNPISRAEYLLSQNGLEIRGEQQTMQDPMFLMEQMELREELEEIPHGSDAESALAAFDA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RVSKMYKQHLASIEQELNDAQWPQAADRVRKLKFIAKLKNEIELVEEKLFG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHFELFGLPPQFSLDGSLLSSQFRELQKRFHPDNFATASERDRLLAVQKAAQINDAYQV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKNPISRAEYLLSQNGLEIRGEQQTMQDPMFLMEQMELREELEEIPHGSDAESALAAFDA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RVSKMYKQHLASIEQELNDAQWPQAADRVRKLKFIAKLKNEIELVEEKLFG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA