Click here to switch to the map view.

The map label for this gene is nhaR

Identifier: 37678866

GI number: 37678866

Start: 680636

End: 681526

Strand: Direct

Name: nhaR

Synonym: VV0682

Alternate gene names: 37678866

Gene position: 680636-681526 (Clockwise)

Preceding gene: 37678863

Following gene: 37678867

Centisome position: 20.29

GC content: 44.33

Gene sequence:

>891_bases
ATGTCACATCTCAATTATAATCACCTCTACTATTTCTGGATGGTTTGTAAGCAAGGTTCCGTTACTAAAGCGGCAGACGC
GCTGTTTCTCACACCACAAACGGTGACTGGACAGATCAAAGCGCTAGAAGATCGCATGAAAGGCAAGCTGACAAAGCGAA
ACGGCCGTACCGTTGAACCCACTGAGCTTGGGCAATTGGTATTCAAATACGCTGACCGTATGTTCGGTCTAAGTTACGAA
ATGCTCGATATCGTCAACTATAGCCAGCATGCCAATATTCTATTTGAAGTCGGTGTTGCTGATGCGTTGTCAAAACGGTT
AGTGAGTAAGGTGCTGAAAACCACCGTACCTCAAGACAAAAAAATCCACTTATGTTGTTACGAATCGACGCACGAATTGC
TGCTGGAACGTTTGGCACAACACAAGCTCGACATGATTCTGTCTGATTGTCCTGTCGACTCGACACAAAGTCCGGGCCTA
TATAGTAAGAAACTGGGTGAGTCGAGCATGAGTTTCTTCTCTTCCACCAAAATAGATAATGCTGAATTTCCCGCAATTTT
GGAGCAGAAAAAACTGTTGATTCCTGGGAGCCGAACAGCGATGGGGCGTAAGGTTTTACAGTGGTTTGATCGCCAAGGGA
TTCAACCTGATGTCTTAGGGGAATTTGATGATGTGGCCCTAATGAAAGCCTTTGCTCGCTACCATGATGATGTCATTTTC
CTTGCCCCGACCGTCTATATCTCAGAAATCGAAGAAGATCTGACTTTACAACTCATTGGCCATGTTGACGATCTCAAAGA
AGAGTATTACGTGATCTTTGCTGAGCGTATGATTCAACATCCCGCAGTAAAGAATGTATGTGACGCAGATTTTAGCCAAT
TGTTTGAATGA

Upstream 100 bases:

>100_bases
GTTATTGCGTTTTAAATTCGGTTTTTCCGATATAATTGGCGACGTCTGTCATATTTGTCACGTTCTCAGGGACGGCAGTG
GTTTCTTTTAAGGAAGGGTT

Downstream 100 bases:

>100_bases
AACCGTTCCCTTGAATACCCCAAATAGATTACTATCTACAAAAATATAAACCTAAATTATAAAATTGTTTAACACAACTA
TCTGCAACAACCGTTGGGAC

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRMKGKLTKRNGRTVEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQHANILFEVGVADALSKRLVSKVLKTTVPQDKKIHLCCYESTHELLLERLAQHKLDMILSDCPVDSTQSPGL
YSKKLGESSMSFFSSTKIDNAEFPAILEQKKLLIPGSRTAMGRKVLQWFDRQGIQPDVLGEFDDVALMKAFARYHDDVIF
LAPTVYISEIEEDLTLQLIGHVDDLKEEYYVIFAERMIQHPAVKNVCDADFSQLFE

Sequences:

>Translated_296_residues
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRMKGKLTKRNGRTVEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQHANILFEVGVADALSKRLVSKVLKTTVPQDKKIHLCCYESTHELLLERLAQHKLDMILSDCPVDSTQSPGL
YSKKLGESSMSFFSSTKIDNAEFPAILEQKKLLIPGSRTAMGRKVLQWFDRQGIQPDVLGEFDDVALMKAFARYHDDVIF
LAPTVYISEIEEDLTLQLIGHVDDLKEEYYVIFAERMIQHPAVKNVCDADFSQLFE
>Mature_295_residues
SHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRMKGKLTKRNGRTVEPTELGQLVFKYADRMFGLSYEM
LDIVNYSQHANILFEVGVADALSKRLVSKVLKTTVPQDKKIHLCCYESTHELLLERLAQHKLDMILSDCPVDSTQSPGLY
SKKLGESSMSFFSSTKIDNAEFPAILEQKKLLIPGSRTAMGRKVLQWFDRQGIQPDVLGEFDDVALMKAFARYHDDVIFL
APTVYISEIEEDLTLQLIGHVDDLKEEYYVIFAERMIQHPAVKNVCDADFSQLFE

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=61.0169491525424, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788297, Length=232, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33778; Mature: 33647

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRMKGKLTKRNGRTVEP
CCCCCCCCEEEEEEEECCCCCCHHCCEEEECCCHHHHHHHHHHHHHHCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQHANILFEVGVADALSKRLVSKVLKTTVPQDK
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
KIHLCCYESTHELLLERLAQHKLDMILSDCPVDSTQSPGLYSKKLGESSMSFFSSTKIDN
EEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHHCCCCC
AEFPAILEQKKLLIPGSRTAMGRKVLQWFDRQGIQPDVLGEFDDVALMKAFARYHDDVIF
CCCCHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCEEE
LAPTVYISEIEEDLTLQLIGHVDDLKEEYYVIFAERMIQHPAVKNVCDADFSQLFE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRMKGKLTKRNGRTVEP
CCCCCCCEEEEEEEECCCCCCHHCCEEEECCCHHHHHHHHHHHHHHCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQHANILFEVGVADALSKRLVSKVLKTTVPQDK
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
KIHLCCYESTHELLLERLAQHKLDMILSDCPVDSTQSPGLYSKKLGESSMSFFSSTKIDN
EEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHHCCCCC
AEFPAILEQKKLLIPGSRTAMGRKVLQWFDRQGIQPDVLGEFDDVALMKAFARYHDDVIF
CCCCHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCEEE
LAPTVYISEIEEDLTLQLIGHVDDLKEEYYVIFAERMIQHPAVKNVCDADFSQLFE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]