Click here to switch to the map view.

The map label for this gene is ung [H]

Identifier: 37678839

GI number: 37678839

Start: 651800

End: 652504

Strand: Direct

Name: ung [H]

Synonym: VV0655

Alternate gene names: 37678839

Gene position: 651800-652504 (Clockwise)

Preceding gene: 37678838

Following gene: 37678840

Centisome position: 19.43

GC content: 46.52

Gene sequence:

>705_bases
ATGGTTTTCAATAGGATTCTCCCCATGACACAGCAACTCACTTGGCACGATGTAATTGGTGCGGAAAAAGAGCAAAGCTA
TTTTCAACAGACACTCAACTTTGTTGAAGCAGAGCGACAAGCTGGCAAAGTGATTTACCCTCCAGCAAAGGATGTCTTCA
ATGCCTTTCGTTATACCGAGTTTCAAGATGTCAAAGTGGTGATCTTAGGACAGGATCCTTACCATGGCCCCAACCAAGCT
CATGGTTTGTGTTTTTCAGTATTACCGGGTATCAAGACACCGCCTTCTTTGGTAAATATGTACAAAGAGTTGGCGCAGGA
TATCCAGGGCTTTCAGATCCCGGCGCATGGTTACCTTGAAGCTTGGGCTAAACAAGGCGTATTGCTGCTCAATACGGTGC
TTACGGTGGAGCAGGGCAAAGCGCATTCTCACGCTTCATTAGGATGGGAAACATTCACTGACAAAGTGATTGAGGCGATC
AATCAGCACCAACAAGGTGTGGTATTCCTATTGTGGGGATCGCATGCACAGAAAAAAGGCCGCTTTATTGATCGCCATAA
GCATGTGGTTCTCACCGCGCCACACCCATCCCCTCTTTCTGCTCACCGCGGCTTTTTGGGCTGTAAGCATTTTTCACAAG
CGAATCAACATTTACTTGATCAAGGAAAGCAAGCAATAGACTGGCAACTACCTTTGTCGCTCTAA

Upstream 100 bases:

>100_bases
ATGCAAGAACGCCACAAAAAAGCCCACAAAGTCACGAAAAAAACCAATAGCTTGTGATGAATTTGGTTAGGGGAGTGACC
TGACATAGAATAACCGCCTG

Downstream 100 bases:

>100_bases
GCACATTTGAATGTAATTTCGTAGAAAACGATGGTTTTTTGAGCGATATCTAAGCCGAATGGCGTTCTATCTTATACACT
TACAACAAATGAGGTGTTAA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MVFNRILPMTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDPYHGPNQA
HGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLEAWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAI
NQHQQGVVFLLWGSHAQKKGRFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL

Sequences:

>Translated_234_residues
MVFNRILPMTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDPYHGPNQA
HGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLEAWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAI
NQHQQGVVFLLWGSHAQKKGRFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL
>Mature_234_residues
MVFNRILPMTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDPYHGPNQA
HGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLEAWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAI
NQHQQGVVFLLWGSHAQKKGRFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=216, Percent_Identity=55.5555555555556, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI6224979, Length=216, Percent_Identity=55.5555555555556, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1788934, Length=220, Percent_Identity=72.2727272727273, Blast_Score=335, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=48.6111111111111, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6323620, Length=233, Percent_Identity=44.6351931330472, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26419; Mature: 26419

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFNRILPMTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTE
CCCCHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHCCC
FQDVKVVILGQDPYHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLE
CCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
AWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAINQHQQGVVFLLWGSHAQKKG
HHHHCCEEEEHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
RFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL
CCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHEECCCCCCC
>Mature Secondary Structure
MVFNRILPMTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTE
CCCCHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHCCC
FQDVKVVILGQDPYHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLE
CCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
AWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAINQHQQGVVFLLWGSHAQKKG
HHHHCCEEEEHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
RFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL
CCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA