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The map label for this gene is arcB [H]

Identifier: 37678828

GI number: 37678828

Start: 639275

End: 641617

Strand: Direct

Name: arcB [H]

Synonym: VV0644

Alternate gene names: 37678828

Gene position: 639275-641617 (Clockwise)

Preceding gene: 37678827

Following gene: 37678829

Centisome position: 19.06

GC content: 46.09

Gene sequence:

>2343_bases
ATGAAACCGATGAAAAACCTTGCCCAGTATTACGTTGATCTACTGGTTAAGCTGGGGATTGTGCGTTTTTCGATGTTGCT
AGCCTTGGCGTTGGTTGCATTAGCTGTGGTGGTCCAAGTGGGCATCACCTTGGTGCTGAAAGGTAATGTGGATGATATCG
ATATTGTCCGCTCAGTCTTTTTCGGTTTGCTCATTACTCCTTGGGCGGTTTATTTCTTGTCAGTGGTGGTGGATCAATTG
GAAGAGTCACGCCAGCGTCTCTCAAAATTGGTTTCTAAATTGAAAGATATGCGTTCACGAGATCAAGAGCTTAATGTTCA
GTTGCAACAGAACATCGAGCAATTGAACCAAGAGATCGAAGAACGTATTCGCGCCGAAGAAGCCAGAGAAGAGGCAATGA
AAGATCTCGAAAACGAGGTGTTTCAACGGGAACGGACCCAAGTGGAACTTGCGGAGCGTACGGCGTTATTGCGCTCTTTT
ATTGATGCCTCTCCGGATTTGATTTACTACCGCAATGCCGAGGGGGTGTTCTCTGGTTGTAACCGAGCGATGGAAGAGTT
GACTGGCAAGAAAGAGCATCAATTGGTCGGCTTAAGCCCTTGGGATGTTTACAGCAAGGAAGTTGCTCAACAAATTGTCG
ATACGGATCAGCAAGTTTTTGCCAATAATCGCGCTTTGACTTACGAGCAGTGGCTTGAATACCCAGATGGTAGAAAACAC
TACTTTGAGCTGCGTAAAGTGCCGTTTTACAGCAAAGATGGGCGTCACCTAGGATTGGTTGGCTTTGGCCGTGACATTAC
AGAACGTAAGCGCCATGAAGAATCATTGGAAAAAGCGAGCCGCGATAAAACCACGTTCATTTCAACCATCAGTCACGAGC
TTAGAACCCCACTTAACGGCATTGTTGGTTTAAGTCGTATGTTATTGGATACGCGCTTAACCGATGAGCAGCGCAAGTAC
ATGCAAACCATCAATGTCAGCGCGATCACCTTAGGTAATATATTCAATGACATCATAGATATGGACAAGTTTGATCGCCG
CAAATTAGAGCTGTTACCCGCTCCGCTTAACTTTGAAGATTTTGTCGCAGAAATCGAAAGCATTTCGGCACTTATGGCAG
AACAAAAAGGATTGCGATTTGATTTAGAGCGTCTGAGTGAACTGCCTAAAGCCATCGAGGTGGATGCCACGCGCTTGCGC
CAAGTCATTTGGAATCTCATCAGCAATGCGATGAAGTTTACCAAAGAGGGTGGAGTGGTCATGACGGTGAGTTCCGAAGT
GGAAGAGGATTTTGCCACCATCATTATTGAAGTAGAAGATACAGGGATCGGGATTCCAGAAGCGGAACTGGATAAGATTT
TTGCCATGTACTACCAAGTCAAATCGGGTAAAGATAACTTGCATGCCGTTGGAACCGGGATTGGTTTGGCGGTTTCACGC
CAGTTGATCAACATGATGGACGGCGATATTACCGTCAGCAGTGAGGAAGGCTTTGGTAGTACGTTCACTATTTCGATTCA
CGTTCCTGTGATTGAATCTGCACCATCGACTGTGGACAAACCGAAAACCCAGCTCTATCTCAGTATCTTTATGGTGGAAG
ACATTGCACTCAACGTCACCGTTGCTCGCTCTCTACTTGAAAGTCTCGGCCACAAAGTGACGGTTGCGATGACAGGGGAC
GAGGCGATACGCTCCTTTGACCCGAGCCGCTACGATTTGGTGTTACTGGATATCCAACTGCCGGATATGACGGGGTTTGA
TGTCGCTGCGTACTATCGCAAACACTATAGCCAATTGCCACCGCTGGTTGCTCTCACTGCCAACGTATTGAAAGATAAGC
GAGAGTATCTAGACAATGGCATGGATGAAGCCATTAGCAAGCCACTTGCGGTACAGGCAATTCAAGATGTGATTGAAAAA
CTGATCATCAAACAAGAAAGCACCACCATCGAGATGGAAGAGGCAGAAGTTGTTGAGATCACAACCAGCCATGTAGAGAA
TCATATTTTGGATCTGGTGATGCTTGAATCCTACGTAGAGATTGTTGGACCGCAGCCCGTCCTCGATAGCATTCGTATGT
TTGAAGAGATGATGCCTGAATACCTTGAAATACTCGATTCCAATATGATTGCAAAAGATCAACCTGGAATTGTTTCCGAA
GCGCATAAAATCAAGGGGGCGGCGGGTTCGATCGGGTTGAAACGAATTCAAAGCGTTGCGCAAAAAGCGCAATCTCCAGA
CATGCCCGCATGGTGGGAAAATATCGCGGACTGGGTAGAAGAAATCAAGAATGAGTATCAAAATGATATTCAGATATTGA
AGAGTTGGTTAGAACAGAGGTGA

Upstream 100 bases:

>100_bases
TTTTCATTACATGTCTGTTCGATGTTTGCACGGCATTAAATGCTAATGTCGCCAACGACTTCACTAGTTCAGGTTGCCCT
CTCATCTTTTGGAGCATTAA

Downstream 100 bases:

>100_bases
AGAAATGAAAAAACCATTAATTGCACTGCTGCCACTATTGCTGTTGGTAGGATGCACCTCCGAGCCAAACGTGAGTTGGC
AGCAAGATAATCGTATCACC

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MKPMKNLAQYYVDLLVKLGIVRFSMLLALALVALAVVVQVGITLVLKGNVDDIDIVRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNVQLQQNIEQLNQEIEERIRAEEAREEAMKDLENEVFQRERTQVELAERTALLRSF
IDASPDLIYYRNAEGVFSGCNRAMEELTGKKEHQLVGLSPWDVYSKEVAQQIVDTDQQVFANNRALTYEQWLEYPDGRKH
YFELRKVPFYSKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLTDEQRKY
MQTINVSAITLGNIFNDIIDMDKFDRRKLELLPAPLNFEDFVAEIESISALMAEQKGLRFDLERLSELPKAIEVDATRLR
QVIWNLISNAMKFTKEGGVVMTVSSEVEEDFATIIIEVEDTGIGIPEAELDKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLINMMDGDITVSSEEGFGSTFTISIHVPVIESAPSTVDKPKTQLYLSIFMVEDIALNVTVARSLLESLGHKVTVAMTGD
EAIRSFDPSRYDLVLLDIQLPDMTGFDVAAYYRKHYSQLPPLVALTANVLKDKREYLDNGMDEAISKPLAVQAIQDVIEK
LIIKQESTTIEMEEAEVVEITTSHVENHILDLVMLESYVEIVGPQPVLDSIRMFEEMMPEYLEILDSNMIAKDQPGIVSE
AHKIKGAAGSIGLKRIQSVAQKAQSPDMPAWWENIADWVEEIKNEYQNDIQILKSWLEQR

Sequences:

>Translated_780_residues
MKPMKNLAQYYVDLLVKLGIVRFSMLLALALVALAVVVQVGITLVLKGNVDDIDIVRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNVQLQQNIEQLNQEIEERIRAEEAREEAMKDLENEVFQRERTQVELAERTALLRSF
IDASPDLIYYRNAEGVFSGCNRAMEELTGKKEHQLVGLSPWDVYSKEVAQQIVDTDQQVFANNRALTYEQWLEYPDGRKH
YFELRKVPFYSKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLTDEQRKY
MQTINVSAITLGNIFNDIIDMDKFDRRKLELLPAPLNFEDFVAEIESISALMAEQKGLRFDLERLSELPKAIEVDATRLR
QVIWNLISNAMKFTKEGGVVMTVSSEVEEDFATIIIEVEDTGIGIPEAELDKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLINMMDGDITVSSEEGFGSTFTISIHVPVIESAPSTVDKPKTQLYLSIFMVEDIALNVTVARSLLESLGHKVTVAMTGD
EAIRSFDPSRYDLVLLDIQLPDMTGFDVAAYYRKHYSQLPPLVALTANVLKDKREYLDNGMDEAISKPLAVQAIQDVIEK
LIIKQESTTIEMEEAEVVEITTSHVENHILDLVMLESYVEIVGPQPVLDSIRMFEEMMPEYLEILDSNMIAKDQPGIVSE
AHKIKGAAGSIGLKRIQSVAQKAQSPDMPAWWENIADWVEEIKNEYQNDIQILKSWLEQR
>Mature_780_residues
MKPMKNLAQYYVDLLVKLGIVRFSMLLALALVALAVVVQVGITLVLKGNVDDIDIVRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNVQLQQNIEQLNQEIEERIRAEEAREEAMKDLENEVFQRERTQVELAERTALLRSF
IDASPDLIYYRNAEGVFSGCNRAMEELTGKKEHQLVGLSPWDVYSKEVAQQIVDTDQQVFANNRALTYEQWLEYPDGRKH
YFELRKVPFYSKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLTDEQRKY
MQTINVSAITLGNIFNDIIDMDKFDRRKLELLPAPLNFEDFVAEIESISALMAEQKGLRFDLERLSELPKAIEVDATRLR
QVIWNLISNAMKFTKEGGVVMTVSSEVEEDFATIIIEVEDTGIGIPEAELDKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLINMMDGDITVSSEEGFGSTFTISIHVPVIESAPSTVDKPKTQLYLSIFMVEDIALNVTVARSLLESLGHKVTVAMTGD
EAIRSFDPSRYDLVLLDIQLPDMTGFDVAAYYRKHYSQLPPLVALTANVLKDKREYLDNGMDEAISKPLAVQAIQDVIEK
LIIKQESTTIEMEEAEVVEITTSHVENHILDLVMLESYVEIVGPQPVLDSIRMFEEMMPEYLEILDSNMIAKDQPGIVSE
AHKIKGAAGSIGLKRIQSVAQKAQSPDMPAWWENIADWVEEIKNEYQNDIQILKSWLEQR

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=783, Percent_Identity=59.7701149425287, Blast_Score=920, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=530, Percent_Identity=27.9245283018868, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1789149, Length=312, Percent_Identity=33.6538461538462, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI87081816, Length=490, Percent_Identity=27.3469387755102, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=38.4920634920635, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788549, Length=354, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=28.3842794759825, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=25.9259259259259, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=389, Percent_Identity=22.107969151671, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=24.1525423728814, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=24.5535714285714, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=24.1228070175439, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=223, Percent_Identity=23.3183856502242, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=140, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88597; Mature: 88597

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMKNLAQYYVDLLVKLGIVRFSMLLALALVALAVVVQVGITLVLKGNVDDIDIVRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
FGLLITPWAVYFLSVVVDQLEESRQRLSKLVSKLKDMRSRDQELNVQLQQNIEQLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERIRAEEAREEAMKDLENEVFQRERTQVELAERTALLRSFIDASPDLIYYRNAEGVFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
NRAMEELTGKKEHQLVGLSPWDVYSKEVAQQIVDTDQQVFANNRALTYEQWLEYPDGRKH
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCEEHHHHHCCCCCCHH
YFELRKVPFYSKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNG
HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTRLTDEQRKYMQTINVSAITLGNIFNDIIDMDKFDRRKLELLPAPLNFED
HHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCHHHHHCCCCCCHHH
FVAEIESISALMAEQKGLRFDLERLSELPKAIEVDATRLRQVIWNLISNAMKFTKEGGVV
HHHHHHHHHHHHHHHCCCEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MTVSSEVEEDFATIIIEVEDTGIGIPEAELDKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
EEECHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHH
QLINMMDGDITVSSEEGFGSTFTISIHVPVIESAPSTVDKPKTQLYLSIFMVEDIALNVT
HHHHHCCCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VARSLLESLGHKVTVAMTGDEAIRSFDPSRYDLVLLDIQLPDMTGFDVAAYYRKHYSQLP
HHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
PLVALTANVLKDKREYLDNGMDEAISKPLAVQAIQDVIEKLIIKQESTTIEMEEAEVVEI
CHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
TTSHVENHILDLVMLESYVEIVGPQPVLDSIRMFEEMMPEYLEILDSNMIAKDQPGIVSE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AHKIKGAAGSIGLKRIQSVAQKAQSPDMPAWWENIADWVEEIKNEYQNDIQILKSWLEQR
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPMKNLAQYYVDLLVKLGIVRFSMLLALALVALAVVVQVGITLVLKGNVDDIDIVRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHH
FGLLITPWAVYFLSVVVDQLEESRQRLSKLVSKLKDMRSRDQELNVQLQQNIEQLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERIRAEEAREEAMKDLENEVFQRERTQVELAERTALLRSFIDASPDLIYYRNAEGVFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
NRAMEELTGKKEHQLVGLSPWDVYSKEVAQQIVDTDQQVFANNRALTYEQWLEYPDGRKH
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHCCCCEEHHHHHCCCCCCHH
YFELRKVPFYSKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNG
HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTRLTDEQRKYMQTINVSAITLGNIFNDIIDMDKFDRRKLELLPAPLNFED
HHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCHHHHHCCCCCCHHH
FVAEIESISALMAEQKGLRFDLERLSELPKAIEVDATRLRQVIWNLISNAMKFTKEGGVV
HHHHHHHHHHHHHHHCCCEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MTVSSEVEEDFATIIIEVEDTGIGIPEAELDKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
EEECHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHH
QLINMMDGDITVSSEEGFGSTFTISIHVPVIESAPSTVDKPKTQLYLSIFMVEDIALNVT
HHHHHCCCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VARSLLESLGHKVTVAMTGDEAIRSFDPSRYDLVLLDIQLPDMTGFDVAAYYRKHYSQLP
HHHHHHHHCCCEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
PLVALTANVLKDKREYLDNGMDEAISKPLAVQAIQDVIEKLIIKQESTTIEMEEAEVVEI
CHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
TTSHVENHILDLVMLESYVEIVGPQPVLDSIRMFEEMMPEYLEILDSNMIAKDQPGIVSE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AHKIKGAAGSIGLKRIQSVAQKAQSPDMPAWWENIADWVEEIKNEYQNDIQILKSWLEQR
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]