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The map label for this gene is wbdQ [H]

Identifier: 37678535

GI number: 37678535

Start: 359606

End: 360088

Strand: Direct

Name: wbdQ [H]

Synonym: VV0351

Alternate gene names: 37678535

Gene position: 359606-360088 (Clockwise)

Preceding gene: 37678534

Following gene: 37678536

Centisome position: 10.72

GC content: 36.44

Gene sequence:

>483_bases
ATGTTTCTAGATAAACGTACGTTTTCGACAGTAATAGAAAGCACGCCACTCATTTCAATCGATTTGGTTATATTTGATCA
AAATAATCAAGCGCTGTTGGGCGAGCGGCTAAATAAACCAGCTCAAGGAAAGTGGTTTGTACCAGGCGGACGGATTTTAA
AAAATGAATCGCTAACAGAGGCATTTGAAAGGTTAACTAAAGAAGAGCTTGGCGAGGTATTTTCACTATCAAAAGCAAGC
CTTTTGGGGCCTTATGACCATTTTTATGACGATAACGTTTTTGGTGACGGCTTTAGCACTCATTATGTTGCCATCGCTTA
TGTTATAAGGTTGAGTAATCCACTTAATGATTTACCTCATAGTATTCAACATGGTAAATATCAATGGTTTGATATAGATA
GCCTATTAATAGATGAAAAAGTCCATAAGCATACAAAATGGTACTTTGAAGCATTGCAGAATACACAGGGACAATTAATA
TGA

Upstream 100 bases:

>100_bases
CTGGGCTGGGAATACAGTATTTCTTTAGAGGTAGGTCTAAGAGATACGTATGGATGGTTTTTAGCAAACCAAGATAATTT
TAGAAAATAGAGAACATAGG

Downstream 100 bases:

>100_bases
TATTACCAATCATTATGGCAGGCGGTTCAGGCACGCGTTTATGGCCATTGTCGCGTGATAACTACCCAAAACAATTTTTA
AAATTGCATGGTGAAAATAC

Product: putative GDP-mannose mannosylhydrolase

Products: GDP; mannose [C]

Alternate protein names: GDPMH [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MFLDKRTFSTVIESTPLISIDLVIFDQNNQALLGERLNKPAQGKWFVPGGRILKNESLTEAFERLTKEELGEVFSLSKAS
LLGPYDHFYDDNVFGDGFSTHYVAIAYVIRLSNPLNDLPHSIQHGKYQWFDIDSLLIDEKVHKHTKWYFEALQNTQGQLI

Sequences:

>Translated_160_residues
MFLDKRTFSTVIESTPLISIDLVIFDQNNQALLGERLNKPAQGKWFVPGGRILKNESLTEAFERLTKEELGEVFSLSKAS
LLGPYDHFYDDNVFGDGFSTHYVAIAYVIRLSNPLNDLPHSIQHGKYQWFDIDSLLIDEKVHKHTKWYFEALQNTQGQLI
>Mature_160_residues
MFLDKRTFSTVIESTPLISIDLVIFDQNNQALLGERLNKPAQGKWFVPGGRILKNESLTEAFERLTKEELGEVFSLSKAS
LLGPYDHFYDDNVFGDGFSTHYVAIAYVIRLSNPLNDLPHSIQHGKYQWFDIDSLLIDEKVHKHTKWYFEALQNTQGQLI

Specific function: It could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. May be involved in the degradation of GDP-mannose and GDP-glucose, diverting the GDP to the synthesis of GDP-fucos

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI87082031, Length=155, Percent_Identity=45.1612903225806, Blast_Score=145, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021161
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 18405; Mature: 18405

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLDKRTFSTVIESTPLISIDLVIFDQNNQALLGERLNKPAQGKWFVPGGRILKNESLTE
CCCCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCCCCCCEECCCCCEECCCHHHH
AFERLTKEELGEVFSLSKASLLGPYDHFYDDNVFGDGFSTHYVAIAYVIRLSNPLNDLPH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
SIQHGKYQWFDIDSLLIDEKVHKHTKWYFEALQNTQGQLI
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLDKRTFSTVIESTPLISIDLVIFDQNNQALLGERLNKPAQGKWFVPGGRILKNESLTE
CCCCHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCCCCCCEECCCCCEECCCHHHH
AFERLTKEELGEVFSLSKASLLGPYDHFYDDNVFGDGFSTHYVAIAYVIRLSNPLNDLPH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
SIQHGKYQWFDIDSLLIDEKVHKHTKWYFEALQNTQGQLI
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDP-mannose; H2O [C]

Specific reaction: GDP-mannose + H2O = GDP + mannose [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9673232; 10222209; 11206551; 11258796 [H]