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The map label for this gene is epsL [H]

Identifier: 37678406

GI number: 37678406

Start: 233075

End: 234274

Strand: Direct

Name: epsL [H]

Synonym: VV0222

Alternate gene names: 37678406

Gene position: 233075-234274 (Clockwise)

Preceding gene: 37678405

Following gene: 37678407

Centisome position: 6.95

GC content: 53.25

Gene sequence:

>1200_bases
GTGAGCGAGTTTCTGACCGTTCGGCTGAGTAGCGAACAATATAGCCCCATTCCTTGGTTGGTTTGGTCATCAAGCCAACA
AGAAGTGATCGCCAGTGGGGAGTTGTCGGATTGGCAACAACTGGACGATCTCAAAAATTATGCCGAGCAGAGGCCGATTG
TGGTGCTGGTCGCGGCCAGTGATGTGGTGTTAACCGAAGTGGACATCCCACCGGGCGCTTCACGTCAGTTTGAGTCGATG
TTGCCTTACCTGCTGGAAGATGAAATCGCCCAAGATGTGGATGATTTGCATTTCTCTGTGTTGGCCAAAGAGAATGGCAA
AGCGCAAGTGTGTGGTGTGGATCGTCGTTGGTTGCAACATATGCTTGATGCATTTCGCGCTCAAGGTTTGGATGTCAAAC
GTGTGCTGCCAGACTCACTGGCGCTGCCACTCGACGACGAAGGCATCAGCGCCGCGCAATTGGGGGAGCAGTGGCTGTTC
CGTCATTCTGCCTGCCAAGGCAGCGCAGTCGACGACAGCTGGATGCCCGTCTATTTGAATGCCCTTGCCGGCGAGCAACC
CCTTTCTGTCGCCTGCTTTAGCTCGTTGCCTGAACAGCAAGGTCAAGCGCATTGGCTGAGTCGCCCAGTGGAAATGACCA
TGGCGTTACTCAGCCAAGGCGTTGCCGATGGTAAATTCTCGCTGCTAACCGGTGAGTTTAAGCCGAAAAGCTCGTTCTTT
AAGCACTGGAAAGTGTGGCAGAAGGTGGCGATCAGTGGCAGCTTATTGATCGCCGCGTTGGTCGCGCAACAAGTGCTCAC
GATTCAGCGCTATGAGTCGCAAGCGCAGGCGTATCGAGAAGAGAGCGAGCGTATTTTCCGTCAAGTGATGCCGGGCCGAA
ACAAGATCCCAACCGTCAGTTACCTCAAACGCCAAATGGAAGACGAAATTCGCCGTTTGTCTGGGGGTGGCACGGGTGAT
TCGATGTTGCAGTGGATGGCACAATTGCCGGGTACCATTGGCCAAGTGAAGAACTTTGAAGTGCTGAGCATCAAATACGA
TGGGAATCGAGGCGAAGTCCGCATTCAGGCGAAAAGTAACGATTTCCAAATTTTTGAACAGGCACGCGTGAAGTTGAGCG
AGCAGTTCGAAGTGGAGCAAGGGCAGCTTAACCGCACTGGCGACGCTGTGATTGGCAGCTTTGTGTTAAAGCGTAAGTGA

Upstream 100 bases:

>100_bases
CAGGTGTTAGTCGAGGACTCTCGGGTGAGAATTCGCAGCCTTATGTACAGTAAAAACAGAGAAACCGTGACCGTTGTGCG
TCGCCGTTTTGGAGGAATCA

Downstream 100 bases:

>100_bases
GGAGCAGATGACAAATTTACTCAATATGTTCCAAGCTTGGTGGAGCAGCATTAGCCAGCGTGAGCAACGTTTAGTGGTGG
TGTGTGGTGTATTCGGTCTT

Product: type II secretory pathway, component EpsL

Products: NA

Alternate protein names: Cholera toxin secretion protein epsL [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSEFLTVRLSSEQYSPIPWLVWSSSQQEVIASGELSDWQQLDDLKNYAEQRPIVVLVAASDVVLTEVDIPPGASRQFESM
LPYLLEDEIAQDVDDLHFSVLAKENGKAQVCGVDRRWLQHMLDAFRAQGLDVKRVLPDSLALPLDDEGISAAQLGEQWLF
RHSACQGSAVDDSWMPVYLNALAGEQPLSVACFSSLPEQQGQAHWLSRPVEMTMALLSQGVADGKFSLLTGEFKPKSSFF
KHWKVWQKVAISGSLLIAALVAQQVLTIQRYESQAQAYREESERIFRQVMPGRNKIPTVSYLKRQMEDEIRRLSGGGTGD
SMLQWMAQLPGTIGQVKNFEVLSIKYDGNRGEVRIQAKSNDFQIFEQARVKLSEQFEVEQGQLNRTGDAVIGSFVLKRK

Sequences:

>Translated_399_residues
MSEFLTVRLSSEQYSPIPWLVWSSSQQEVIASGELSDWQQLDDLKNYAEQRPIVVLVAASDVVLTEVDIPPGASRQFESM
LPYLLEDEIAQDVDDLHFSVLAKENGKAQVCGVDRRWLQHMLDAFRAQGLDVKRVLPDSLALPLDDEGISAAQLGEQWLF
RHSACQGSAVDDSWMPVYLNALAGEQPLSVACFSSLPEQQGQAHWLSRPVEMTMALLSQGVADGKFSLLTGEFKPKSSFF
KHWKVWQKVAISGSLLIAALVAQQVLTIQRYESQAQAYREESERIFRQVMPGRNKIPTVSYLKRQMEDEIRRLSGGGTGD
SMLQWMAQLPGTIGQVKNFEVLSIKYDGNRGEVRIQAKSNDFQIFEQARVKLSEQFEVEQGQLNRTGDAVIGSFVLKRK
>Mature_398_residues
SEFLTVRLSSEQYSPIPWLVWSSSQQEVIASGELSDWQQLDDLKNYAEQRPIVVLVAASDVVLTEVDIPPGASRQFESML
PYLLEDEIAQDVDDLHFSVLAKENGKAQVCGVDRRWLQHMLDAFRAQGLDVKRVLPDSLALPLDDEGISAAQLGEQWLFR
HSACQGSAVDDSWMPVYLNALAGEQPLSVACFSSLPEQQGQAHWLSRPVEMTMALLSQGVADGKFSLLTGEFKPKSSFFK
HWKVWQKVAISGSLLIAALVAQQVLTIQRYESQAQAYREESERIFRQVMPGRNKIPTVSYLKRQMEDEIRRLSGGGTGDS
MLQWMAQLPGTIGQVKNFEVLSIKYDGNRGEVRIQAKSNDFQIFEQARVKLSEQFEVEQGQLNRTGDAVIGSFVLKRK

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3297

COG function: function code U; Type II secretory pathway, component PulL

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP L family [H]

Homologues:

Organism=Escherichia coli, GI87082244, Length=298, Percent_Identity=23.1543624161074, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007812 [H]

Pfam domain/function: PF05134 GspL [H]

EC number: NA

Molecular weight: Translated: 44812; Mature: 44681

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLTVRLSSEQYSPIPWLVWSSSQQEVIASGELSDWQQLDDLKNYAEQRPIVVLVAAS
CCCEEEEEECCCCCCCCCEEEECCCCCHHEECCCCHHHHHHHHHHHHHHCCCEEEEEEEC
DVVLTEVDIPPGASRQFESMLPYLLEDEIAQDVDDLHFSVLAKENGKAQVCGVDRRWLQH
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCHHHHHH
MLDAFRAQGLDVKRVLPDSLALPLDDEGISAAQLGEQWLFRHSACQGSAVDDSWMPVYLN
HHHHHHHCCCCHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ALAGEQPLSVACFSSLPEQQGQAHWLSRPVEMTMALLSQGVADGKFSLLTGEFKPKSSFF
HHCCCCCCCHHHHHHCCHHCCCHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
KHWKVWQKVAISGSLLIAALVAQQVLTIQRYESQAQAYREESERIFRQVMPGRNKIPTVS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YLKRQMEDEIRRLSGGGTGDSMLQWMAQLPGTIGQVKNFEVLSIKYDGNRGEVRIQAKSN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCEEEEEEEECCCCCEEEEEECCC
DFQIFEQARVKLSEQFEVEQGQLNRTGDAVIGSFVLKRK
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SEFLTVRLSSEQYSPIPWLVWSSSQQEVIASGELSDWQQLDDLKNYAEQRPIVVLVAAS
CCEEEEEECCCCCCCCCEEEECCCCCHHEECCCCHHHHHHHHHHHHHHCCCEEEEEEEC
DVVLTEVDIPPGASRQFESMLPYLLEDEIAQDVDDLHFSVLAKENGKAQVCGVDRRWLQH
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCHHHHHH
MLDAFRAQGLDVKRVLPDSLALPLDDEGISAAQLGEQWLFRHSACQGSAVDDSWMPVYLN
HHHHHHHCCCCHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ALAGEQPLSVACFSSLPEQQGQAHWLSRPVEMTMALLSQGVADGKFSLLTGEFKPKSSFF
HHCCCCCCCHHHHHHCCHHCCCHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
KHWKVWQKVAISGSLLIAALVAQQVLTIQRYESQAQAYREESERIFRQVMPGRNKIPTVS
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YLKRQMEDEIRRLSGGGTGDSMLQWMAQLPGTIGQVKNFEVLSIKYDGNRGEVRIQAKSN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHCCCCEEEEEEEECCCCCEEEEEECCC
DFQIFEQARVKLSEQFEVEQGQLNRTGDAVIGSFVLKRK
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]