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The map label for this gene is epsM [H]

Identifier: 37678407

GI number: 37678407

Start: 234282

End: 234773

Strand: Direct

Name: epsM [H]

Synonym: VV0223

Alternate gene names: 37678407

Gene position: 234282-234773 (Clockwise)

Preceding gene: 37678406

Following gene: 37678408

Centisome position: 6.98

GC content: 50.0

Gene sequence:

>492_bases
ATGACAAATTTACTCAATATGTTCCAAGCTTGGTGGAGCAGCATTAGCCAGCGTGAGCAACGTTTAGTGGTGGTGTGTGG
TGTATTCGGTCTTATCGGGCTGATTTACTGGGGCGTTTTGCAGCCCATCAATGCGCGCGCTGAGCAAGCTCAGTTACGCA
TCCAAAGTGAGAAACAGCTACTCAGTTGGGTGAGTGAGAAAGCCGATGAGCTCACCGGTTTACGTGCCAGTGGCGGTGTA
TCGTTTTCCAATCAGCCGCTAAACCAAGTCATTGCGTCATCCGCGCGCCAATTTAAGGTGGAGCTACAGCGTGTTCAGCC
CCGCAATGAGATGTTGCAAGTGTGGGTGGCTCCGATGCCATTTAACCGTTTAGTGGACTGGCTGACCTTTTTGAAAGAGA
AGCAAGGCATTGAAGTGGAATTCATGGACATCGACCGTGGTAAAGAGTCCGGTCTAGTGGAAGTTAACCGATTACAGTTT
AAGCGAGGCTAG

Upstream 100 bases:

>100_bases
GTGAAGTTGAGCGAGCAGTTCGAAGTGGAGCAAGGGCAGCTTAACCGCACTGGCGACGCTGTGATTGGCAGCTTTGTGTT
AAAGCGTAAGTGAGGAGCAG

Downstream 100 bases:

>100_bases
GGTGAAGCGCGCGATTATTTACAGCCTGATTTTTATTCTCTTTTTTAGCATCAGTTTGCTGTCGAGCATTCCGGTTAGCT
TTGCGCTCAATTACTTGCCA

Product: type II secretory pathway, component EpsM

Products: NA

Alternate protein names: Cholera toxin secretion protein epsM [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTNLLNMFQAWWSSISQREQRLVVVCGVFGLIGLIYWGVLQPINARAEQAQLRIQSEKQLLSWVSEKADELTGLRASGGV
SFSNQPLNQVIASSARQFKVELQRVQPRNEMLQVWVAPMPFNRLVDWLTFLKEKQGIEVEFMDIDRGKESGLVEVNRLQF
KRG

Sequences:

>Translated_163_residues
MTNLLNMFQAWWSSISQREQRLVVVCGVFGLIGLIYWGVLQPINARAEQAQLRIQSEKQLLSWVSEKADELTGLRASGGV
SFSNQPLNQVIASSARQFKVELQRVQPRNEMLQVWVAPMPFNRLVDWLTFLKEKQGIEVEFMDIDRGKESGLVEVNRLQF
KRG
>Mature_162_residues
TNLLNMFQAWWSSISQREQRLVVVCGVFGLIGLIYWGVLQPINARAEQAQLRIQSEKQLLSWVSEKADELTGLRASGGVS
FSNQPLNQVIASSARQFKVELQRVQPRNEMLQVWVAPMPFNRLVDWLTFLKEKQGIEVEFMDIDRGKESGLVEVNRLQFK
RG

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3149

COG function: function code U; Type II secretory pathway, component PulM

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP M family [H]

Homologues:

Organism=Escherichia coli, GI1789339, Length=148, Percent_Identity=30.4054054054054, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007690
- InterPro:   IPR023229 [H]

Pfam domain/function: PF04612 GspM [H]

EC number: NA

Molecular weight: Translated: 18722; Mature: 18591

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLLNMFQAWWSSISQREQRLVVVCGVFGLIGLIYWGVLQPINARAEQAQLRIQSEKQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LSWVSEKADELTGLRASGGVSFSNQPLNQVIASSARQFKVELQRVQPRNEMLQVWVAPMP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
FNRLVDWLTFLKEKQGIEVEFMDIDRGKESGLVEVNRLQFKRG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEHHHHHCCCC
>Mature Secondary Structure 
TNLLNMFQAWWSSISQREQRLVVVCGVFGLIGLIYWGVLQPINARAEQAQLRIQSEKQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LSWVSEKADELTGLRASGGVSFSNQPLNQVIASSARQFKVELQRVQPRNEMLQVWVAPMP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
FNRLVDWLTFLKEKQGIEVEFMDIDRGKESGLVEVNRLQFKRG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8406031; 10952301 [H]