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The map label for this gene is ubiC [H]

Identifier: 37678304

GI number: 37678304

Start: 126413

End: 126964

Strand: Direct

Name: ubiC [H]

Synonym: VV0120

Alternate gene names: 37678304

Gene position: 126413-126964 (Clockwise)

Preceding gene: 37678302

Following gene: 37678305

Centisome position: 3.77

GC content: 47.64

Gene sequence:

>552_bases
TTGAATACTAGTATGAATCAGCCAAACTCGCTCTATCTTGCTTTGTTAATAGAAGCAAAATGGCAAAATCCTGAAGATTT
TCACTTTTCTAGTGACTTTGCTAAGCACTGGTTACTGGAGCAAGGCTCCTTGTCTCGCCGTTTGGCGCGTCATTGCCAAC
ATCTGACCGTTGAGTTGATGCGCAATGAAAAAAGTGGTGTGGGCCAATTAACAATGCAAGAGACTCAGGGGTTATCCCCT
GAGATTTGCTTGATCCGAGAGGTGGTGCTATCCGGTGATCAAACACCGTGGGTGCTGGGAAGAACGTTGATCCCTGAAAC
CACCTTAGCTGATCAGCCCTACGACTTAGCCACGCTGGGTGATATTCCTCTGGGTCTCACCGTGTTTAGTGCAGAGCAAG
TTGAGCGTGACGCATTGCAAGTGGCTTGGATTGAAACACCGCAAGGGCGTTTACTCGCCAGACGTTCTCGTTTATGGATG
AACCACAAACCGATGTTAGTGGCAGAACTGTTTTTACCTGATGCACCGATTTACTCCAGGGAGAGTGTGTAA

Upstream 100 bases:

>100_bases
GGCGGTCCAAATGTCACTATAAGTTATTACAATCTTTACGGTGGCTCATTACCGTAAAGTGACGCTTTATTGTACGCACA
ACGCGACTAAAAGCTACTAA

Downstream 100 bases:

>100_bases
ATGTCAGTAGAAAAGGCCAAGGCGTATTGGCAACTGATGAGGATGGACCGACCAATTGGCACGTTACTGCTGCTTTGGCC
AACCTTGTGGGCGTTGATTA

Product: chorismate-pyruvate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNTSMNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELMRNEKSGVGQLTMQETQGLSP
EICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLGDIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWM
NHKPMLVAELFLPDAPIYSRESV

Sequences:

>Translated_183_residues
MNTSMNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELMRNEKSGVGQLTMQETQGLSP
EICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLGDIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWM
NHKPMLVAELFLPDAPIYSRESV
>Mature_183_residues
MNTSMNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELMRNEKSGVGQLTMQETQGLSP
EICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLGDIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWM
NHKPMLVAELFLPDAPIYSRESV

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=144, Percent_Identity=34.0277777777778, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 20822; Mature: 20822

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSMNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELM
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RNEKSGVGQLTMQETQGLSPEICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLG
HCCCCCCCEEEEHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEC
DIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWMNHKPMLVAELFLPDAPIYSR
CCCCCEEEECHHHHHHHCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
ESV
CCC
>Mature Secondary Structure
MNTSMNQPNSLYLALLIEAKWQNPEDFHFSSDFAKHWLLEQGSLSRRLARHCQHLTVELM
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RNEKSGVGQLTMQETQGLSPEICLIREVVLSGDQTPWVLGRTLIPETTLADQPYDLATLG
HCCCCCCCEEEEHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEC
DIPLGLTVFSAEQVERDALQVAWIETPQGRLLARRSRLWMNHKPMLVAELFLPDAPIYSR
CCCCCEEEECHHHHHHHCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
ESV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA