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The map label for this gene is ubiA

Identifier: 37678305

GI number: 37678305

Start: 126965

End: 127819

Strand: Direct

Name: ubiA

Synonym: VV0121

Alternate gene names: 37678305

Gene position: 126965-127819 (Clockwise)

Preceding gene: 37678304

Following gene: 37678307

Centisome position: 3.78

GC content: 50.53

Gene sequence:

>855_bases
ATGTCAGTAGAAAAGGCCAAGGCGTATTGGCAACTGATGAGGATGGACCGACCAATTGGCACGTTACTGCTGCTTTGGCC
AACCTTGTGGGCGTTGATTATTGCCGCGGAAGGGACACCCGATTGGCATGTTTTGCTGGTCTTTGTGTTGGGCGTGGTGT
TGATGCGCAGTGCCGGTTGCGTGATCAATGACTTTGCCGATCGTAAAGTGGATGGTCATGTTAAGCGCACTCAGCAGCGA
CCTCTGCCTTCAGGTCGCGTGACGGCGAAAGAAGCGGTCATTCTGTTTTTGCTGTTAGGGATCAGCTCTTTTTTGTTGGT
GTTGACCATGAACCCACTCACTATCCAGCTCTCATTTGCCGGTATCGTGCTGGCGTTCATTTACCCTTTTATGAAGCGCT
ATACCCATCTACCGCAGTTGTTTCTTGGCTTAGCGTTTAGCTGGGCAATCCCGATGGCGTGGGCCGCGCAGGCGAATGAG
TTGCCTTGGGTGGTGTGGTTTGTGTTTGCGATTAATGCGTTGTGGACCATTGCGTACGATACCCAATATGCGATGGTTGA
TCGCGATGATGACATCCAGATCGGTGTTAAATCGACCGCTATTTTGTTTGGCCGCCACGACAAGTTGATCATCGGCCTGT
TGCAATTGCTAACGCTAGTGATGCTGGTTTGGCTTGGCTTGCATTACCAATTGGGGCAAAGTTTTTATTGGAGTGTGCTG
GCCGCTGGTGCGCTGTTTGTATATCAGCAGCATTTGATCCGTCATCGTCAGCGAGAGTTGTGTTTCCAAGCGTTTCTCAA
TAATAACTATGTCGGGATGGTGCTGGCGCTCGGGTTATTTGTCGCGTTTTGGTAG

Upstream 100 bases:

>100_bases
ACTCGCCAGACGTTCTCGTTTATGGATGAACCACAAACCGATGTTAGTGGCAGAACTGTTTTTACCTGATGCACCGATTT
ACTCCAGGGAGAGTGTGTAA

Downstream 100 bases:

>100_bases
ACCGCGCTGAGTTTACTTGGCGCTCGTTGCACAGAAAAAGAAAAACAAAGGCATCCACGGGATGCCTTTGTTGTATCCCC
TTCCTACTTGAAGCTGCAGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGCVINDFADRKVDGHVKRTQQR
PLPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFAGIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANE
LPWVVWFVFAINALWTIAYDTQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVL
AAGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW

Sequences:

>Translated_284_residues
MSVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGCVINDFADRKVDGHVKRTQQR
PLPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFAGIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANE
LPWVVWFVFAINALWTIAYDTQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVL
AAGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW
>Mature_283_residues
SVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGCVINDFADRKVDGHVKRTQQRP
LPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFAGIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANEL
PWVVWFVFAINALWTIAYDTQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVLA
AGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=284, Percent_Identity=34.8591549295775, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=62.3239436619718, Blast_Score=350, Evalue=7e-98,
Organism=Escherichia coli, GI1786631, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17553718, Length=279, Percent_Identity=36.2007168458781, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=34.4086021505376, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=336, Percent_Identity=29.4642857142857, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=43.1654676258993, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=42.7536231884058, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=31.0344827586207, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21355567, Length=284, Percent_Identity=38.7323943661972, Blast_Score=184, Evalue=6e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32386; Mature: 32255

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGC
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
VINDFADRKVDGHVKRTQQRPLPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFA
EEEHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANELPWVVWFVFAINALWTIAYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEC
TQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVL
CEEEEECCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGC
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
VINDFADRKVDGHVKRTQQRPLPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFA
EEEHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
GIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANELPWVVWFVFAINALWTIAYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEC
TQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVL
CEEEEECCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA