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The map label for this gene is glpG [H]

Identifier: 37678302

GI number: 37678302

Start: 124951

End: 125793

Strand: Direct

Name: glpG [H]

Synonym: VV0118

Alternate gene names: 37678302

Gene position: 124951-125793 (Clockwise)

Preceding gene: 161486673

Following gene: 37678304

Centisome position: 3.72

GC content: 50.06

Gene sequence:

>843_bases
ATGCAGCGTCTTATTGTGTTGAACAATCCAAGGATGGCGCAGGCTTTTATCGACTACATGGCTTCTCGACAAATTGATTT
GCGAATGATGCCTGAAGGTGAAGGGCAGTTTGCCTTATGGCTGATGGACGATCAGCATTGGGTTGAAACCGAAGCAGAGC
TCAAACAGTTTTTGGCTAATCCTGGTGACAGTAAATACAGCGCTGCATCTTGGGATATGGCGGAAACGCGCAAAACTCAG
TTCAGTTACCGAAGCCCCAGTTTACTGGCGATGGTGAAAGCGAAAGCGGGTCCTGTCACCATGGCGGTGATGGTCGCCTG
TGTGGCGGTTTATGTGCTCATGATGTTTGGTTGGGAAAGCGCGCTTTTAAGTGCGATGCATTTTCCGGCGGAAGCCGCGC
AACAATGGCAATTATGGCGTTGGGTGAGCCATGCACTGCTGCACTTCTCGGTGACCCACATTGTGTTTAACTTACTGTGG
TGGTGGCAGTTTGGTGGCGACATTGAACAGAGATTGGGTAGCGGTAAACTACTGCAAATCTTTGTCATTTCGGCCGCACT
CTCTGGCGCTGGTCAGTTTTGGGTTGAAGGGGCCAATTTTGGTGGCTTATCTGGTGTGGTTTATGCCTTGCTCGGTTACG
CTTGGATTTTAGGTTATCGCGTGCCTCACCTTGGCTTATCAGTGCCTAGGCCCGTGGTCGCTTTTATGCTGGTATGGCTC
ATTCTTGGTTACGTTCAACCCTTTATGGCGATTGCCAATACTGCTCATCTCGTGGGTTTGTTGTCTGGTATGGGGCTGGC
CTATCTGGATTCCACCAAGCAAAAACATCAAAAAGCGGCCTAG

Upstream 100 bases:

>100_bases
CGTTGAAGCAAGCTGATCCCTTTAGAAAGAAGGGCTTTTGCCTAACGGCCTTTGATGTGGAAGAATGAGGTTCGATTTTT
CGTCTAACTGAGGTTTCTCT

Downstream 100 bases:

>100_bases
GCCGCTTTTTGCTTTATAACATAAATAGAATCAGCCGAGCTGAACATGCTACTGATAGAGGTATTTGGTAAACAGCAGGT
CAGCAATGACGGTTTTGCCC

Product: uncharacterized membrane protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQRLIVLNNPRMAQAFIDYMASRQIDLRMMPEGEGQFALWLMDDQHWVETEAELKQFLANPGDSKYSAASWDMAETRKTQ
FSYRSPSLLAMVKAKAGPVTMAVMVACVAVYVLMMFGWESALLSAMHFPAEAAQQWQLWRWVSHALLHFSVTHIVFNLLW
WWQFGGDIEQRLGSGKLLQIFVISAALSGAGQFWVEGANFGGLSGVVYALLGYAWILGYRVPHLGLSVPRPVVAFMLVWL
ILGYVQPFMAIANTAHLVGLLSGMGLAYLDSTKQKHQKAA

Sequences:

>Translated_280_residues
MQRLIVLNNPRMAQAFIDYMASRQIDLRMMPEGEGQFALWLMDDQHWVETEAELKQFLANPGDSKYSAASWDMAETRKTQ
FSYRSPSLLAMVKAKAGPVTMAVMVACVAVYVLMMFGWESALLSAMHFPAEAAQQWQLWRWVSHALLHFSVTHIVFNLLW
WWQFGGDIEQRLGSGKLLQIFVISAALSGAGQFWVEGANFGGLSGVVYALLGYAWILGYRVPHLGLSVPRPVVAFMLVWL
ILGYVQPFMAIANTAHLVGLLSGMGLAYLDSTKQKHQKAA
>Mature_280_residues
MQRLIVLNNPRMAQAFIDYMASRQIDLRMMPEGEGQFALWLMDDQHWVETEAELKQFLANPGDSKYSAASWDMAETRKTQ
FSYRSPSLLAMVKAKAGPVTMAVMVACVAVYVLMMFGWESALLSAMHFPAEAAQQWQLWRWVSHALLHFSVTHIVFNLLW
WWQFGGDIEQRLGSGKLLQIFVISAALSGAGQFWVEGANFGGLSGVVYALLGYAWILGYRVPHLGLSVPRPVVAFMLVWL
ILGYVQPFMAIANTAHLVGLLSGMGLAYLDSTKQKHQKAA

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=271, Percent_Identity=43.1734317343173, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31348; Mature: 31348

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLIVLNNPRMAQAFIDYMASRQIDLRMMPEGEGQFALWLMDDQHWVETEAELKQFLAN
CCCEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
PGDSKYSAASWDMAETRKTQFSYRSPSLLAMVKAKAGPVTMAVMVACVAVYVLMMFGWES
CCCCCCCCCCCCHHHHHHHHCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLSAMHFPAEAAQQWQLWRWVSHALLHFSVTHIVFNLLWWWQFGGDIEQRLGSGKLLQI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
FVISAALSGAGQFWVEGANFGGLSGVVYALLGYAWILGYRVPHLGLSVPRPVVAFMLVWL
HHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ILGYVQPFMAIANTAHLVGLLSGMGLAYLDSTKQKHQKAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRLIVLNNPRMAQAFIDYMASRQIDLRMMPEGEGQFALWLMDDQHWVETEAELKQFLAN
CCCEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
PGDSKYSAASWDMAETRKTQFSYRSPSLLAMVKAKAGPVTMAVMVACVAVYVLMMFGWES
CCCCCCCCCCCCHHHHHHHHCCCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLSAMHFPAEAAQQWQLWRWVSHALLHFSVTHIVFNLLWWWQFGGDIEQRLGSGKLLQI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHH
FVISAALSGAGQFWVEGANFGGLSGVVYALLGYAWILGYRVPHLGLSVPRPVVAFMLVWL
HHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ILGYVQPFMAIANTAHLVGLLSGMGLAYLDSTKQKHQKAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA