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The map label for this gene is dppB [H]

Identifier: 37678229

GI number: 37678229

Start: 54385

End: 55362

Strand: Direct

Name: dppB [H]

Synonym: VV0045

Alternate gene names: 37678229

Gene position: 54385-55362 (Clockwise)

Preceding gene: 37678228

Following gene: 37678230

Centisome position: 1.62

GC content: 48.77

Gene sequence:

>978_bases
ATGTTTTCGTTTCTGGTCAAGCGCCTGTTTCAGGCACTGATAGTGATGTTTGTGATCAGTTTAGTGGCGTTTGCCATTCA
GGATAACCTAGGCGACCCGTTGCGTGAGCTAGTGGGCCAGTCAGTTTCAGAAGCAGAGCGCCAAGCGCTGCGAGATGAAC
TTGGTCTAAACGATCCCTTTATCACCAAATACACACGCTTTATCGGCGCTGCATTGCAGGGCGATTTAGGCACTTCATAC
TTTTTTAAACGTCCTGCGGTGGATGTGATTCTTGATAAACTCGTTGCCACCCTAGAGTTGGTGTTTGGCGCGACCGTATT
AATCATCGTCTTTTCGATCCCGCTTGGGGTTTATTCCGCGATTCATCCGAAGAGTTTCTTTACCAAAGTGGTCATGGCAG
GCAGCAGCATCGGTATTTCGATCCCCGTTTTCTTAACCGCGATCATGCTGATGTACGTCTTCTCGATTGAGCTGCAATGG
CTGCCATCCTATGGGCGAGGGGAAACGTATAACCTACTCGGTTGGGAATCGGGCTTTTTTACCATTGATGGCTTAAAGCA
CTTAGTGCTGCCTTGTATCGCGTTGGCGTCGATCATGCTGCCACTGTTTATTCGTCTGGTGCGTTCAGAAATGCTGGAAG
TGCTGAGTTCGGAATACATCAAATTTGCCAAGGCGAAAGGTCTCGCGCTGAACAAAATTTATTACCAACATGCGCTCAAA
AATACCATGCTGCCAGTGTTAACCGTTGGTGGCGTGCAGATTGGTACCATGGTGGCGTACACCATTTTGACTGAAACCGT
GTTCCAATGGCCGGGAACGGGCTTCCTTTTCCTTGAGGCGATCAACCGCGTGGATACCCCACTGATCACCGCTTACGTCA
TTTTTGTCGGACTGATTTTCGTGGTGACCAACACCATCGTTGACCTGCTGTATGGTTTAATCAACCCGACCGTGAACTTA
ACAGGCAAAGGAGCATAA

Upstream 100 bases:

>100_bases
TCAACTTTGTTTCAGTCGGGTTGAGCGCCGTTTTCAGACTGAAGTTTATATGGCCGTGATAGCGAACGGGCATAGTCATG
GATAGCAAAAGGGGCAAGGA

Downstream 100 bases:

>100_bases
TCATGGAACACGTTAATAAAGCTCCTTCTGCATGGGAACGCTTTAAAGAATCGGATTTTCTTTACTATTTTAAACGCGAC
AAAGTGGCGATGAGCAGCTT

Product: peptide ABC transporter, permease component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFSFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFITKYTRFIGAALQGDLGTSY
FFKRPAVDVILDKLVATLELVFGATVLIIVFSIPLGVYSAIHPKSFFTKVVMAGSSIGISIPVFLTAIMLMYVFSIELQW
LPSYGRGETYNLLGWESGFFTIDGLKHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFAKAKGLALNKIYYQHALK
NTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVTNTIVDLLYGLINPTVNL
TGKGA

Sequences:

>Translated_325_residues
MFSFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFITKYTRFIGAALQGDLGTSY
FFKRPAVDVILDKLVATLELVFGATVLIIVFSIPLGVYSAIHPKSFFTKVVMAGSSIGISIPVFLTAIMLMYVFSIELQW
LPSYGRGETYNLLGWESGFFTIDGLKHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFAKAKGLALNKIYYQHALK
NTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVTNTIVDLLYGLINPTVNL
TGKGA
>Mature_325_residues
MFSFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPFITKYTRFIGAALQGDLGTSY
FFKRPAVDVILDKLVATLELVFGATVLIIVFSIPLGVYSAIHPKSFFTKVVMAGSSIGISIPVFLTAIMLMYVFSIELQW
LPSYGRGETYNLLGWESGFFTIDGLKHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFAKAKGLALNKIYYQHALK
NTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIFVVTNTIVDLLYGLINPTVNL
TGKGA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=36.2017804154303, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=31.25, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=31.8885448916409, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=34.0298507462687, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787497, Length=323, Percent_Identity=30.9597523219814, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=30.7692307692308, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35888; Mature: 35888

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
ITKYTRFIGAALQGDLGTSYFFKRPAVDVILDKLVATLELVFGATVLIIVFSIPLGVYSA
HHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHPKSFFTKVVMAGSSIGISIPVFLTAIMLMYVFSIELQWLPSYGRGETYNLLGWESGFF
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCE
TIDGLKHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFAKAKGLALNKIYYQHALK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
VVTNTIVDLLYGLINPTVNLTGKGA
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFSFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQALRDELGLNDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
ITKYTRFIGAALQGDLGTSYFFKRPAVDVILDKLVATLELVFGATVLIIVFSIPLGVYSA
HHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHPKSFFTKVVMAGSSIGISIPVFLTAIMLMYVFSIELQWLPSYGRGETYNLLGWESGFF
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCE
TIDGLKHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFAKAKGLALNKIYYQHALK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLIF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
VVTNTIVDLLYGLINPTVNLTGKGA
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9680333 [H]