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The map label for this gene is engA

Identifier: 161486654

GI number: 161486654

Start: 774843

End: 776333

Strand: Direct

Name: engA

Synonym: VV0770

Alternate gene names: 161486654

Gene position: 774843-776333 (Clockwise)

Preceding gene: 37678953

Following gene: 37678955

Centisome position: 23.1

GC content: 47.75

Gene sequence:

>1491_bases
ATGATACCTGTTGTTGCTCTAGTCGGTCGTCCAAACGTAGGTAAATCTACGTTGTTTAACCGATTGACTCGCTCTCGTGA
CGCATTGGTGGCGGACTTTCCAGGTCTGACTCGTGACCGTAAATATGGTCAAGCCAAAGTAGGTGAGCACGACTTTATTG
TGATTGATACGGGTGGTATCGATGGTTCTGAAGAAGGCGTTGAAACCAAAATGGCAGAACAGTCACTTGCTGCGATCCGC
GAAGCTGACGTTGTGTTGTTCATGGTGGATGGTCGCGCAGGATTGACGCCATCCGATGAGGCGATTGCTGCCCATTTACG
TAAAATCGAAAAAGCCACCATGCTGGTGGTGAACAAAGTGGATGGCATCGATGCGGATGCTGCCAGCGCAGACTTTTGGC
AACTGGGCGTTGATGAGATGTACCAAATTGCCGCAGCGCATGGTCGTGGTGTGACTGCGCTGATTGAACGTGCACTCGAT
CCATTCTTTGACAATCTTCTCAGTACTAACAGCGAAGGTGAGATCGAAGATCTGACCAATATGGAAGATGAAGAAGCAGA
ACAGCAAGAGTACTCTGAAGAAGATGCCGAAGAGTCACTGAAGCGACTGCAAGACCAGCCAATTAAGCTTGCTATTATTG
GTCGTCCGAACGTGGGTAAATCAACGCTGACTAACCGTATTTTGGGTGAAGAACGCGTTGTTGTGTACGATATGCCAGGA
ACCACGCGTGACTCCATTTACATTCCAATGGAACGTGATGGTCGCGAATACGTGTTGATCGACACCGCAGGTGTTCGTCG
TCGCGGTAAAGTACATGAAACGGTTGAAAAATTCTCTGTTGTTAAAACATTGAAAGCCGTTGAAGATGCCAACGTTGTAC
TGTTAGTGATTGACGCTCGAGAAAACATCTCGGATCAGGATTTGAGCTTATTGGGCTTCGCACTTAATGCGGGTCGTTCT
ATCGTGCTGGCCGTGAACAAGTGGGATGGCTTGGATAACGAAGTGAAAGAGAATGTGAAGAAAGAGCTTGATCGTCGTCT
TGGCTTCGTCGATTTTGCTCGCATCCACTTCATCTCTGCGTTGCACGGCACTGGCGTAGGCCATTTGTTTGAATCAGTTC
AAGAAGCTTACCGCTCTGCAACCACTCGTGTAGGGACATCGGTACTGACGCGTATCATGAAGATGGCAACGGAAGATCAC
CAACCGCCGATGGTTCGTGGCCGTCGTGTGAAACTGAAATATGCGCACGCAGGTGGTTATAACCCACCAATCGTGGTGAT
CCATGGTAACCAAGTTCGTGAATTACCGGATTCTTACAAACGTTATCTAATGAACTACTTCCGTAAGTCACTAGATATCA
TGGGTACGCCGATTCGTATTCAGTTCCAAAACAGTGATAACCCGTTTGAGAACCGTGTCAATAAGATGACCCTTTCTCAA
GAGCGTGCACGTAAGCGCATGATGAGTGCGGTAAAAAATCGCAAGAAATAA

Upstream 100 bases:

>100_bases
TGACAAGACGATTGTGGTTATAGGTAAAAAGCTGGTTTGAAGTGCTATCAAGCAAGTGGTTACCTATAACTACAGATCAA
AGATTATTGTAGAGGTTGTT

Downstream 100 bases:

>100_bases
TCTGAACTGTTTTTGATGCCCAAGTTTTACTTGGGCATTTTTTTATTTTCCGTTTCCCAATATGGATAACATGCCACATC
ATTCGTTGAGCGGATGATGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MIPVVALVGRPNVGKSTLFNRLTRSRDALVADFPGLTRDRKYGQAKVGEHDFIVIDTGGIDGSEEGVETKMAEQSLAAIR
EADVVLFMVDGRAGLTPSDEAIAAHLRKIEKATMLVVNKVDGIDADAASADFWQLGVDEMYQIAAAHGRGVTALIERALD
PFFDNLLSTNSEGEIEDLTNMEDEEAEQQEYSEEDAEESLKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPG
TTRDSIYIPMERDGREYVLIDTAGVRRRGKVHETVEKFSVVKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNAGRS
IVLAVNKWDGLDNEVKENVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATEDH
QPPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVRELPDSYKRYLMNYFRKSLDIMGTPIRIQFQNSDNPFENRVNKMTLSQ
ERARKRMMSAVKNRKK

Sequences:

>Translated_496_residues
MIPVVALVGRPNVGKSTLFNRLTRSRDALVADFPGLTRDRKYGQAKVGEHDFIVIDTGGIDGSEEGVETKMAEQSLAAIR
EADVVLFMVDGRAGLTPSDEAIAAHLRKIEKATMLVVNKVDGIDADAASADFWQLGVDEMYQIAAAHGRGVTALIERALD
PFFDNLLSTNSEGEIEDLTNMEDEEAEQQEYSEEDAEESLKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPG
TTRDSIYIPMERDGREYVLIDTAGVRRRGKVHETVEKFSVVKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNAGRS
IVLAVNKWDGLDNEVKENVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATEDH
QPPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVRELPDSYKRYLMNYFRKSLDIMGTPIRIQFQNSDNPFENRVNKMTLSQ
ERARKRMMSAVKNRKK
>Mature_496_residues
MIPVVALVGRPNVGKSTLFNRLTRSRDALVADFPGLTRDRKYGQAKVGEHDFIVIDTGGIDGSEEGVETKMAEQSLAAIR
EADVVLFMVDGRAGLTPSDEAIAAHLRKIEKATMLVVNKVDGIDADAASADFWQLGVDEMYQIAAAHGRGVTALIERALD
PFFDNLLSTNSEGEIEDLTNMEDEEAEQQEYSEEDAEESLKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPG
TTRDSIYIPMERDGREYVLIDTAGVRRRGKVHETVEKFSVVKTLKAVEDANVVLLVIDARENISDQDLSLLGFALNAGRS
IVLAVNKWDGLDNEVKENVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATEDH
QPPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVRELPDSYKRYLMNYFRKSLDIMGTPIRIQFQNSDNPFENRVNKMTLSQ
ERARKRMMSAVKNRKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=495, Percent_Identity=71.9191919191919, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=144, Percent_Identity=34.7222222222222, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=34.6774193548387, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=30.5555555555556, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55486; Mature: 55486

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRSRDALVADFPGLTRDRKYGQAKVGEHDFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
DGSEEGVETKMAEQSLAAIREADVVLFMVDGRAGLTPSDEAIAAHLRKIEKATMLVVNKV
CCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEECC
DGIDADAASADFWQLGVDEMYQIAAAHGRGVTALIERALDPFFDNLLSTNSEGEIEDLTN
CCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
MEDEEAEQQEYSEEDAEESLKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPG
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMERDGREYVLIDTAGVRRRGKVHETVEKFSVVKTLKAVEDANVVLLVIDAR
CCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ENISDQDLSLLGFALNAGRSIVLAVNKWDGLDNEVKENVKKELDRRLGFVDFARIHFISA
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATEDHQPPMVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVRELPDSYKRYLMNYFRKSLDIMGTPIRIQFQNSDNPFENRVNKMTLSQ
CCCEEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
ERARKRMMSAVKNRKK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRSRDALVADFPGLTRDRKYGQAKVGEHDFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
DGSEEGVETKMAEQSLAAIREADVVLFMVDGRAGLTPSDEAIAAHLRKIEKATMLVVNKV
CCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEEEECC
DGIDADAASADFWQLGVDEMYQIAAAHGRGVTALIERALDPFFDNLLSTNSEGEIEDLTN
CCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
MEDEEAEQQEYSEEDAEESLKRLQDQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPG
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMERDGREYVLIDTAGVRRRGKVHETVEKFSVVKTLKAVEDANVVLLVIDAR
CCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
ENISDQDLSLLGFALNAGRSIVLAVNKWDGLDNEVKENVKKELDRRLGFVDFARIHFISA
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATEDHQPPMVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVRELPDSYKRYLMNYFRKSLDIMGTPIRIQFQNSDNPFENRVNKMTLSQ
CCCEEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
ERARKRMMSAVKNRKK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA