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The map label for this gene is alaS [C]

Identifier: 37678955

GI number: 37678955

Start: 776455

End: 777339

Strand: Direct

Name: alaS [C]

Synonym: VV0771

Alternate gene names: 37678955

Gene position: 776455-777339 (Clockwise)

Preceding gene: 161486654

Following gene: 37678956

Centisome position: 23.15

GC content: 47.91

Gene sequence:

>885_bases
ATGCAGATAACAGCCACTAAGGTTCGCTTTTGTCATCAGGCCTGGCAGTTGGAGAGTGACATTGTACTCACTTCAGTCAA
TGAACATTCTCTTTATGTCGTGACTCAGCACACACCATTTCATCCGGTTAGTCATATTTGGCCAGATCACCCTGCAGATC
GGGGAAGCCTTATCGCGGATGGCAAAGAGTGGCCCATCATCGGTTGTTGGGTTGGCGCTGTAGAGTGCTCTACAGGGCGC
CTGTTTGTTGATCAAGCGATACCGGTAAAGCGAGATACAGAGGGATGGAGCTTCGTAGTGGTTCATGAAATTGAAGCCGA
GCGTGGGCAACTTTCTGTTGGATGCAAAGTACGATTGAGTGTCGACAAAGAATATCAACAAAGCCTGAGTCGAGGTCACA
GTGCAGGGCATTTAGCCTATCTGGCATTGAATAAAGTCTTGGCGCAAGGTTACTGGCGCAAAGATGCCGATCGCAAAGAC
CCTCATGGTTACTATGATTTTAACAGTTATGCTCAAGAGAGTAGCGTTGTGACGCCAGAGTGTTGTCTAGACACCTATCG
ACTGGGAAAAACGCTACGCAAAAGAGGGCTGAACAGTGCTGATGTGGTGGAAAATATTCAAGAGATTGAATCCGAGGTCA
ATGTACAGCTTGAGCACTGGCTTGCTCGCGGATCCGAAATATACATGAACTGTCATGGCGAATATTTAACCGACTCTCGT
TACTGGCAATGTGATTTGGGAGAAGCCTCAACGGCGATTATCCCTTGTGGGGGAACGCATGCTGCTGGGCTGTTCGAAAT
GAAAGAGATTGCCGTTACATTGGTGCTGTTGGATGAGCAGACCATTGAAATGCACACGCAAGTCACGCCCAACAGAGAAA
AATGA

Upstream 100 bases:

>100_bases
AAGTTTTACTTGGGCATTTTTTTATTTTCCGTTTCCCAATATGGATAACATGCCACATCATTCGTTGAGCGGATGATGCC
TCTTCGTTGAGATAAGAAAT

Downstream 100 bases:

>100_bases
TCTTTATATAAAAAAACAAAAATACAGATTTAAATATGCCTATATAGATTTTTGTGTTGTTTAAAATTGAAATGCAGCAT
ATGTAACTTATGCTTTCGGG

Product: metal-dependent hydrolase

Products: AMP; diphosphate; L-alanyl-tRNAAla [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQITATKVRFCHQAWQLESDIVLTSVNEHSLYVVTQHTPFHPVSHIWPDHPADRGSLIADGKEWPIIGCWVGAVECSTGR
LFVDQAIPVKRDTEGWSFVVVHEIEAERGQLSVGCKVRLSVDKEYQQSLSRGHSAGHLAYLALNKVLAQGYWRKDADRKD
PHGYYDFNSYAQESSVVTPECCLDTYRLGKTLRKRGLNSADVVENIQEIESEVNVQLEHWLARGSEIYMNCHGEYLTDSR
YWQCDLGEASTAIIPCGGTHAAGLFEMKEIAVTLVLLDEQTIEMHTQVTPNREK

Sequences:

>Translated_294_residues
MQITATKVRFCHQAWQLESDIVLTSVNEHSLYVVTQHTPFHPVSHIWPDHPADRGSLIADGKEWPIIGCWVGAVECSTGR
LFVDQAIPVKRDTEGWSFVVVHEIEAERGQLSVGCKVRLSVDKEYQQSLSRGHSAGHLAYLALNKVLAQGYWRKDADRKD
PHGYYDFNSYAQESSVVTPECCLDTYRLGKTLRKRGLNSADVVENIQEIESEVNVQLEHWLARGSEIYMNCHGEYLTDSR
YWQCDLGEASTAIIPCGGTHAAGLFEMKEIAVTLVLLDEQTIEMHTQVTPNREK
>Mature_294_residues
MQITATKVRFCHQAWQLESDIVLTSVNEHSLYVVTQHTPFHPVSHIWPDHPADRGSLIADGKEWPIIGCWVGAVECSTGR
LFVDQAIPVKRDTEGWSFVVVHEIEAERGQLSVGCKVRLSVDKEYQQSLSRGHSAGHLAYLALNKVLAQGYWRKDADRKD
PHGYYDFNSYAQESSVVTPECCLDTYRLGKTLRKRGLNSADVVENIQEIESEVNVQLEHWLARGSEIYMNCHGEYLTDSR
YWQCDLGEASTAIIPCGGTHAAGLFEMKEIAVTLVLLDEQTIEMHTQVTPNREK

Specific function: Unknown

COG id: COG2872

COG function: function code R; Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.1.1.7 [C]

Molecular weight: Translated: 33200; Mature: 33200

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITATKVRFCHQAWQLESDIVLTSVNEHSLYVVTQHTPFHPVSHIWPDHPADRGSLIAD
CCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEC
GKEWPIIGCWVGAVECSTGRLFVDQAIPVKRDTEGWSFVVVHEIEAERGQLSVGCKVRLS
CCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEECEEEEEE
VDKEYQQSLSRGHSAGHLAYLALNKVLAQGYWRKDADRKDPHGYYDFNSYAQESSVVTPE
ECHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHH
CCLDTYRLGKTLRKRGLNSADVVENIQEIESEVNVQLEHWLARGSEIYMNCHGEYLTDSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEHHHHHHCCCEEEEEECCCEECCCC
YWQCDLGEASTAIIPCGGTHAAGLFEMKEIAVTLVLLDEQTIEMHTQVTPNREK
EEEEECCCCCEEEEECCCCCCHHHHHHHHEEEEEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MQITATKVRFCHQAWQLESDIVLTSVNEHSLYVVTQHTPFHPVSHIWPDHPADRGSLIAD
CCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHCCCCCCCCCCCEEEC
GKEWPIIGCWVGAVECSTGRLFVDQAIPVKRDTEGWSFVVVHEIEAERGQLSVGCKVRLS
CCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEECEEEEEE
VDKEYQQSLSRGHSAGHLAYLALNKVLAQGYWRKDADRKDPHGYYDFNSYAQESSVVTPE
ECHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHH
CCLDTYRLGKTLRKRGLNSADVVENIQEIESEVNVQLEHWLARGSEIYMNCHGEYLTDSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEHHHHHHCCCEEEEEECCCEECCCC
YWQCDLGEASTAIIPCGGTHAAGLFEMKEIAVTLVLLDEQTIEMHTQVTPNREK
EEEEECCCCCEEEEECCCCCCHHHHHHHHEEEEEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; @ALAN01.txt*L-alanine!; tRNAAla [C]

Specific reaction: ATP + @ALAN01.txt*L-alanine! + tRNAAla = AMP + diphosphate + L-alanyl-tRNAAla [C]

General reaction: Aminoacylation; Esterification [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA