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The map label for this gene is rnhA [H]

Identifier: 161486651

GI number: 161486651

Start: 810698

End: 811216

Strand: Direct

Name: rnhA [H]

Synonym: VV0806

Alternate gene names: 161486651

Gene position: 810698-811216 (Clockwise)

Preceding gene: 37678985

Following gene: 37678994

Centisome position: 24.17

GC content: 44.32

Gene sequence:

>519_bases
ATGCGAGCGTACTTCATTTTTCACATCACATCCTTATCTGATGAGAGACAAGCACGTTGCGTTGTCAAAATAGAAAAGGA
ACAAACAATGAAAAATGAATCATGCGCGTTGTATATTGCAGTCACAGCGTCCAGTGTCGATGGTGGAATTGGTTTGGTGG
TGTACAACAAAGCTGGTGAGTTAATGGACCAGCAATGTTTACCGATGCAGGGATACACCAGTAATACTGAGCTAGAGCTA
ATTGCGTTGGTGGAGTGTATGCAATATGCGCGTGATGGCGATGTCATCTATACCAGCAGTGATTTTTGTGTTCGTGGATT
TAACGAATGGATTGATACCTGGAAGCAAAAAGGTTGGCGTAAGTCAGACAAAAAGCCAGTAGCAAATCGCGATTTATGGC
AACAGGTAGATGCGCTCCGAGCCGAGAAATACGTTGAGGTAATCAGAGCAACCCCAAGTACGCATCCAGCGTTAAGCGAA
GCGTATAACATGGCAAAACAAGCGCTTAGCAAGTTGTAG

Upstream 100 bases:

>100_bases
TGATAGCCTGCGAGGGCTGCTTTCAGTAGGGCCTTTAAGATCTTCTCGCGTAGCGGAGAAAAGGTGGTCATAACGTGTCC
TTATGGTTCAGGGCACAGTG

Downstream 100 bases:

>100_bases
ATGAATTTGGTTAAGCTCAGCTTTCAGAACGTACTCAGCCCTTGCAATACAAGGGTTTAGCTCTCTCTCAAGAGCGAGTG
CTGGCAATTAAATAGGCCGA

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRAYFIFHITSLSDERQARCVVKIEKEQTMKNESCALYIAVTASSVDGGIGLVVYNKAGELMDQQCLPMQGYTSNTELEL
IALVECMQYARDGDVIYTSSDFCVRGFNEWIDTWKQKGWRKSDKKPVANRDLWQQVDALRAEKYVEVIRATPSTHPALSE
AYNMAKQALSKL

Sequences:

>Translated_172_residues
MRAYFIFHITSLSDERQARCVVKIEKEQTMKNESCALYIAVTASSVDGGIGLVVYNKAGELMDQQCLPMQGYTSNTELEL
IALVECMQYARDGDVIYTSSDFCVRGFNEWIDTWKQKGWRKSDKKPVANRDLWQQVDALRAEKYVEVIRATPSTHPALSE
AYNMAKQALSKL
>Mature_172_residues
MRAYFIFHITSLSDERQARCVVKIEKEQTMKNESCALYIAVTASSVDGGIGLVVYNKAGELMDQQCLPMQGYTSNTELEL
IALVECMQYARDGDVIYTSSDFCVRGFNEWIDTWKQKGWRKSDKKPVANRDLWQQVDALRAEKYVEVIRATPSTHPALSE
AYNMAKQALSKL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=68, Percent_Identity=38.2352941176471, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 19560; Mature: 19560

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYFIFHITSLSDERQARCVVKIEKEQTMKNESCALYIAVTASSVDGGIGLVVYNKAGE
CCEEEEEEEECCCCCCCCEEEEEECHHHHCCCCCEEEEEEEEECCCCCCEEEEEECCCCH
LMDQQCLPMQGYTSNTELELIALVECMQYARDGDVIYTSSDFCVRGFNEWIDTWKQKGWR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
KSDKKPVANRDLWQQVDALRAEKYVEVIRATPSTHPALSEAYNMAKQALSKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAYFIFHITSLSDERQARCVVKIEKEQTMKNESCALYIAVTASSVDGGIGLVVYNKAGE
CCEEEEEEEECCCCCCCCEEEEEECHHHHCCCCCEEEEEEEEECCCCCCEEEEEECCCCH
LMDQQCLPMQGYTSNTELELIALVECMQYARDGDVIYTSSDFCVRGFNEWIDTWKQKGWR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
KSDKKPVANRDLWQQVDALRAEKYVEVIRATPSTHPALSEAYNMAKQALSKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]