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The map label for this gene is pabC [H]

Identifier: 161486633

GI number: 161486633

Start: 1298423

End: 1299226

Strand: Direct

Name: pabC [H]

Synonym: VV1278

Alternate gene names: 161486633

Gene position: 1298423-1299226 (Clockwise)

Preceding gene: 37679461

Following gene: 37679463

Centisome position: 38.71

GC content: 46.14

Gene sequence:

>804_bases
ATGTATTGGGTCAATGGCGTTGTAGCAACGGAAGTTTCTCTCTCAGACCGATCATTCCAGTATGGTGATGGCTGCTTTAC
CACCATGAAAACATTGAATGGCCAAATCGAGCATTGGCCATTACATATTGAACGTATGGAAGCGTGCTTACAGGTTCTTT
CCATTCCTCTCCCTGACTGGGCATTGGTTGAACAGTGGCTACACCAGGCCGCGTTACCAGATGCACGAGGTGGGTTGAAA
TTGCACATTAGCCGCGGAGAAGGCGGTCGCGGTTACAGTCCCAGTGGTGTTGCTACGCCTAATGTTACCATCTCGAGTTT
TTCCTATCCTGTTCATTATTCCCAATGGCAACAACATGGTGTCGAGCTCGGTGTGTGTCAAACACCACTCGGTATCAATC
CTATTCTTGCAGGACACAAGCATAATAATCGTCTTGAGCAAGTTCTTTGCAAAGCGGAGCTCGATGCGTTGGGTTACCTA
GATGGGGTGACGTTTAATGTGCAAAACCATGTGATTGAAACTACAATAGCCAATCTTTTTTGGGTTAAGAATGGAGTACT
TTTTACTCCCGATCTCACTTTAAGTGGGGTATCTGGTGTGATGCGTCGCTTGGTGATGGACGAAGCACAACGTCGTGCGA
TAGCGTGTCAGGAAATCAAAGCAGACTTGTCCTCTTTATTGGCGGCTGAGGAAGTATTCATGACCAACTCTTTACTGGGT
GTTGCTCCTATCAATCAGATTCTCGAAACCCGTTACCCAATTGGTACCACAACACGATATTTTCAAGGAATTTTTAACTC
GTGA

Upstream 100 bases:

>100_bases
TTTAAGAAAATCTAACACTCATTTAGGTTTCTGAAACTTGTATTTAAACGGCTTGATGCTTAGCATTAAGCCGTTTTGTT
TTTATTGGGATATAGATAGC

Downstream 100 bases:

>100_bases
TAAAAAAAATAATAGGGCTGCTCTTTATTGCCGCGTTGATGATAGGCGTTGCTACTTTTTGGGCATATTCGCAAACCAAA
ACCTACGTTAACCAACCGCT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKAELDALGYL
DGVTFNVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMDEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFQGIFNS

Sequences:

>Translated_267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKAELDALGYL
DGVTFNVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMDEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFQGIFNS
>Mature_267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKAELDALGYL
DGVTFNVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMDEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFQGIFNS

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=261, Percent_Identity=34.8659003831418, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI48994963, Length=165, Percent_Identity=28.4848484848485, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29553; Mature: 29553

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDW
CEEECEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCH
ALVEQWLHQAALPDARGGLKLHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHG
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECEECCCCHHHHHHCC
VELGVCQTPLGINPILAGHKHNNRLEQVLCKAELDALGYLDGVTFNVQNHVIETTIANLF
CEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHH
WVKNGVLFTPDLTLSGVSGVMRRLVMDEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAPINQILETRYPIGTTTRYFQGIFNS
HHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDW
CEEECEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCH
ALVEQWLHQAALPDARGGLKLHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHG
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECEECCCCHHHHHHCC
VELGVCQTPLGINPILAGHKHNNRLEQVLCKAELDALGYLDGVTFNVQNHVIETTIANLF
CEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHH
WVKNGVLFTPDLTLSGVSGVMRRLVMDEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAPINQILETRYPIGTTTRYFQGIFNS
HHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]