Click here to switch to the map view.

The map label for this gene is lgt

Identifier: 37523962

GI number: 37523962

Start: 4622236

End: 4623045

Strand: Reverse

Name: lgt

Synonym: gll4393

Alternate gene names: 37523962

Gene position: 4623045-4622236 (Counterclockwise)

Preceding gene: 37523963

Following gene: 37523960

Centisome position: 99.23

GC content: 63.21

Gene sequence:

>810_bases
GTGCCCATGGAAACCGGCTTCACCTCCCCGGGACCGCTTATCGTTCAGATTGGCGGCTTTGCGGTCCGCTGGTACAGCTT
GCTCATTCTCGCGGGAATCATTGCCGGTACGCTGCTGTCGCAGAAACTGGCCCCCGAGCGCAAGGTCGCCCCGGAGGTGC
TCTCGGATCTGGTCGTCTGGCTGGTGGTGGGGGCGATTCCGATGGCGCGGCTGTACTATGTACTCTTCGAGTGGCAGCGC
TTCGCCGGGGAACCCTGGTGGAAGGTGTTTGCCATCTGGGAAGGGGGCATCGCCATCCACGGCGCCATCTTGGGGGGGCT
GCTCGCCGGTTGGCTCTTTTGCCGCCGCAACGGCTATTCGCTTCTGACGATGATAGATCTGGCCGCCCCGGGGCTCATCC
TCGGCCAGGCCATTGGCCGCTGGGGCAACTTTTTCAATTCCGAAGCCTACGGTGCCCCCACCAATCTGCCCTGGAAACTG
TTTATCCCCGAGGCCAACCGCCCGCCCGGGATGGCCGCCTTTGCCTACTACCACCCGACGTTTCTGTACGAATCGCTCTG
GAACCTGGGGGTACTGGCCCTGTTGCTGTTTGTGTTCTTTCGCTTTAAAAATCTGCGGCCCGGCAGCATCGCCTGTCTGT
ACGCCCTGGCCTACAGTGTCGGACGCTTCTGGATCGAAGGGTTGCGCCTCGACTCGCTGATGGTGGGTCCGCTGCGCACC
GCCCAGTTGGTCAGCCTCGCCGGAATCGTGCTGGGGGCAGTCGGTCTGTGGTGGCTCAATCGCCGCAGTGCCCGACAAGA
GGCGCCGTGA

Upstream 100 bases:

>100_bases
GCCAGGGCATGGAGTGGGACGTGGTCGGCTGTGAAAGCTTCGTGAGCGATCCCGGCCGCTGGTCGCGTCTGCGCCCCGGT
GAATTGATTCCCACCTGACG

Downstream 100 bases:

>100_bases
GCCTCGAACAAGCGGCCCCGGTGCGTCAGGCGCACCGGGGCCGGCTGGTATTGCCTCGACCCATCTGCCGCTAGAGTTCG
AGCAGGATGGCAAAAGTGTT

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVWLVVGAIPMARLYYVLFEWQR
FAGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYSLLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKL
FIPEANRPPGMAAFAYYHPTFLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRT
AQLVSLAGIVLGAVGLWWLNRRSARQEAP

Sequences:

>Translated_269_residues
MPMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVWLVVGAIPMARLYYVLFEWQR
FAGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYSLLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKL
FIPEANRPPGMAAFAYYHPTFLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRT
AQLVSLAGIVLGAVGLWWLNRRSARQEAP
>Mature_268_residues
PMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVWLVVGAIPMARLYYVLFEWQRF
AGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYSLLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKLF
IPEANRPPGMAAFAYYHPTFLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRTA
QLVSLAGIVLGAVGLWWLNRRSARQEAP

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=286, Percent_Identity=29.020979020979, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_GLOVI (Q7ND43)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_927339.1
- GeneID:   2602796
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll4393
- NMPDR:   fig|251221.1.peg.4393
- HOGENOM:   HBG450278
- OMA:   CARAYYV
- ProtClustDB:   PRK00052
- BioCyc:   GVIO251221:GLL4393-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 29833; Mature: 29701

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x181aaf4c)-; HASH(0x183632f8)-; HASH(0x1877861c)-; HASH(0x189088bc)-; HASH(0x18de405c)-; HASH(0x18b3c9f4)-; HASH(0x4061e5bc)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVW
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LVVGAIPMARLYYVLFEWQRFAGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCH
LLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKLFIPEANRPPGMAAFAYYHPT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHH
FLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHH
AQLVSLAGIVLGAVGLWWLNRRSARQEAP
HHHHHHHHHHHHHHHHHHHCCHHHCCCCH
>Mature Secondary Structure 
PMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVW
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LVVGAIPMARLYYVLFEWQRFAGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYS
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCH
LLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKLFIPEANRPPGMAAFAYYHPT
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHH
FLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHH
AQLVSLAGIVLGAVGLWWLNRRSARQEAP
HHHHHHHHHHHHHHHHHHHCCHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292