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The map label for this gene is gufA [H]

Identifier: 37523849

GI number: 37523849

Start: 4505610

End: 4506392

Strand: Direct

Name: gufA [H]

Synonym: glr4280

Alternate gene names: 37523849

Gene position: 4505610-4506392 (Clockwise)

Preceding gene: 37523848

Following gene: 37523856

Centisome position: 96.71

GC content: 62.71

Gene sequence:

>783_bases
ATGCACCCAGTCTTCCTCGGAACCTTCGCCAGTCTGATCGCCGGCCTCGCCACGGCTGTAGGGGCCTTGCCGGTGCTCTT
TGCCCGCAAGCTCTCCCAGAAGACCCAGTCGATTTTGCTGGGTTTCGGCGGCGGGGTAATGCTCGCCGCTTCCGCTTTTT
CGCTGATCGTGCCGGGCACGGATATTGCCGTCAAGCAGGGTTACTCCCGGCCCGTCGCGGCTCTGATCATGGCGGTCGGC
ATTCTGCTGGGCGGCCTATTTTTGTGGCTGGCCAACCGCTACTTTCCCCACGAGCACTTCATCAAAGGCCCGGAGGGCGC
CAACCCCAGTCCTGAGCGTCTCAAGCGCATCTGGTTATTCGTGGGGGCTATCGCCCTGCACAACTTTCCGGAGGGGATGG
CGGTCGGCGTCAGCTTCGGGGGCGGCAGCATCGCCGAAGGTTTGCCGGTGGCGGTGGGCATCGGTCTGCAGAACATGCCC
GAGGGGCTGGTGGTGGCCGTCGCCCTGTTGGGCCAGGGCTATTCGGTGGGCTACGCGCTGTGGGTGACGTTGCTTTCGGG
TCTGGTCGAACCGATTGGCGGTCTACTGGGGGCGAGCGTGGTGAGTGTTTCCCAGGCGATCTTGCCCTGGGGGATGGCCT
TTGCCGCCGGGGCGATGCTGTTTGTGATCAGCGACGAAATTATCCCGGAGTCGCATCGTCAGGGCTTTGACCTCGAAGGG
ACGGTGGGGGTGATGGTGGGATTTGTGGTAATGATGTTTCTCGATATTGCCCTGGGCAGCTAA

Upstream 100 bases:

>100_bases
TTTGCGTTACGCTCGGCTCGGCCTCGTTGTCGCCACGCGGCAGGTGCTGGCCACTACCCTCACCCTGCTCGGCATCGAGC
CGCGCGAATCGATGTAGGCC

Downstream 100 bases:

>100_bases
AAAACTTACCAGCTAAATCGGGCGTTGTTGCCGGTGCGGGGGGGGGGACTGAGTACCGCCGCTGCGCTGCCCAGGGCCAT
CACCTGCCCAAACTCCAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MHPVFLGTFASLIAGLATAVGALPVLFARKLSQKTQSILLGFGGGVMLAASAFSLIVPGTDIAVKQGYSRPVAALIMAVG
ILLGGLFLWLANRYFPHEHFIKGPEGANPSPERLKRIWLFVGAIALHNFPEGMAVGVSFGGGSIAEGLPVAVGIGLQNMP
EGLVVAVALLGQGYSVGYALWVTLLSGLVEPIGGLLGASVVSVSQAILPWGMAFAAGAMLFVISDEIIPESHRQGFDLEG
TVGVMVGFVVMMFLDIALGS

Sequences:

>Translated_260_residues
MHPVFLGTFASLIAGLATAVGALPVLFARKLSQKTQSILLGFGGGVMLAASAFSLIVPGTDIAVKQGYSRPVAALIMAVG
ILLGGLFLWLANRYFPHEHFIKGPEGANPSPERLKRIWLFVGAIALHNFPEGMAVGVSFGGGSIAEGLPVAVGIGLQNMP
EGLVVAVALLGQGYSVGYALWVTLLSGLVEPIGGLLGASVVSVSQAILPWGMAFAAGAMLFVISDEIIPESHRQGFDLEG
TVGVMVGFVVMMFLDIALGS
>Mature_260_residues
MHPVFLGTFASLIAGLATAVGALPVLFARKLSQKTQSILLGFGGGVMLAASAFSLIVPGTDIAVKQGYSRPVAALIMAVG
ILLGGLFLWLANRYFPHEHFIKGPEGANPSPERLKRIWLFVGAIALHNFPEGMAVGVSFGGGSIAEGLPVAVGIGLQNMP
EGLVVAVALLGQGYSVGYALWVTLLSGLVEPIGGLLGASVVSVSQAILPWGMAFAAGAMLFVISDEIIPESHRQGFDLEG
TVGVMVGFVVMMFLDIALGS

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=159, Percent_Identity=45.2830188679245, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI229577418, Length=159, Percent_Identity=45.2830188679245, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI187936949, Length=149, Percent_Identity=27.5167785234899, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI55741750, Length=149, Percent_Identity=27.5167785234899, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789419, Length=249, Percent_Identity=30.9236947791165, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=319, Percent_Identity=33.2288401253918, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24652846, Length=164, Percent_Identity=46.9512195121951, Blast_Score=141, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 26858; Mature: 26858

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVFLGTFASLIAGLATAVGALPVLFARKLSQKTQSILLGFGGGVMLAASAFSLIVPGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCC
DIAVKQGYSRPVAALIMAVGILLGGLFLWLANRYFPHEHFIKGPEGANPSPERLKRIWLF
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHH
VGAIALHNFPEGMAVGVSFGGGSIAEGLPVAVGIGLQNMPEGLVVAVALLGQGYSVGYAL
HHHHHHHCCCCCEEEEEECCCCCHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHH
WVTLLSGLVEPIGGLLGASVVSVSQAILPWGMAFAAGAMLFVISDEIIPESHRQGFDLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHCCCCCCCC
TVGVMVGFVVMMFLDIALGS
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHPVFLGTFASLIAGLATAVGALPVLFARKLSQKTQSILLGFGGGVMLAASAFSLIVPGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCC
DIAVKQGYSRPVAALIMAVGILLGGLFLWLANRYFPHEHFIKGPEGANPSPERLKRIWLF
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHH
VGAIALHNFPEGMAVGVSFGGGSIAEGLPVAVGIGLQNMPEGLVVAVALLGQGYSVGYAL
HHHHHHHCCCCCEEEEEECCCCCHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHH
WVTLLSGLVEPIGGLLGASVVSVSQAILPWGMAFAAGAMLFVISDEIIPESHRQGFDLEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHCCCCCCCC
TVGVMVGFVVMMFLDIALGS
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]