Click here to switch to the map view.

The map label for this gene is argS

Identifier: 37523848

GI number: 37523848

Start: 4503801

End: 4505606

Strand: Direct

Name: argS

Synonym: gvip558

Alternate gene names: 37523848

Gene position: 4503801-4505606 (Clockwise)

Preceding gene: 37523847

Following gene: 37523849

Centisome position: 96.67

GC content: 63.57

Gene sequence:

>1806_bases
ATGACAGCCCTATCACTGCAGCAACAACTCGCCGAGAGCATTTACACCGCTCTCGGCACCGCTTTTGAGGCCGGGCAACT
GGGACAACTCACCCAGTTGCCCCCGCGCCAATCCGTCGTCGTCGAAAAGCCGAAAGTCCCCGAGCACGGCGACTACGCGA
CACCGGTGGCGATGAGCCTGGCCAAGCCCTGTCGCCTGGCGCCCCTTGCCATTGCCGAGGCTATCGCTTCCTACCTGGCA
AGCGACGAGATCGGCGTCGAGGTGGCAAAACCGGGCTTTATCAATTTGCGCCTCGGCCACCGGTTCGTGGCCGTCGAATT
GCAGAACATCTTAGAACTCAAGGGTGACTACGGCCGGACGGTGCCGCAGCAGCCCGAGCGCATCCTGCTCGAATTTGTCT
CGGCCAATCCGACCGGGCCGCTGCACCTGGGCCACGGGCGCTGGGCGGCGCTCGGCTCCAGCCTGGAGCGGATCTTGCAG
TTCGCAGGCTATACAGTCGATAGCGAATTTTATATCAACGATGCGGGCAACCAGATGCAGCTGTTGGGCCTCTCGCTCAA
GCAGCGCTATTTGCAGGTTCTAGGTGAGGCGGTCGAGTTGCCCGACGGCGGCTACAAGGGCAGCTATCTGAAGGAGCTGG
CGGAGCAACTGGTGGCCGACAAGGGCGACAGCCTGGGCGGCGAACCCGTCGAGTGGTTCAGCGCTTACGCCGAGGGCCGG
CTGTTGGAGCAGCAGAAGATCACCTTGCAGCAATTTCGCACCGAGTTCGACCGCTGGTATTCCGAGCGCTCGCTGCACTG
TGCGGGGGCCATCGAAGCGGCTCTTGCCGATCTGGAGGCGCGGGGGATGCTCTACCGGGCGGCCCGCTCGCGCCAGGAGC
AAAGCGGCGAAATTACCGGCCGCTCCAAAAAGGTGCAGGCCCCGGCCGCCTTCGAGGAAGAAGACGGCGGTGGCGAGGCG
CTGTTTTTCAAGGCGGCGGATTTTGGCGACGAGATGGACCGGGTGGTCAAGCGCGCCGACGGCAACACCACCTACCTCGC
CGCCGACATCGCCTACCACTGGGACAAGTACCAGCGCGGCTACGGGCGGCTCATCAACATCTGGGGCGCCGATCACCACG
GCTACGTGCCGCGGATGAAGGCGGTCGCCCAGGCGCTCGGACACCCGGCCGACTCCCTGGAGATCTTGATCGGCCAGATG
GTGCGGCTGTTCAAGACCAACCCCGAGACCGGCCAAAAAGAAGAAATGCGCATGTCGAAGCGCCGGGGTGAACTGGTGAG
CGTCGACGATCTGATCGAAGAAGTGGGGGTCGATGCCGGGCGGTGGTTCTTGCTCAGCCAATCGCTCAATACCACGGTCA
ATTTCGACCTCGACCTGGCCCAGTCCGAAAAATTCGACAACCCCGTCTTCTATGTCCAGTACAACCACGCCCGCTGCTGC
AGCATTCTGCGCAAGGCCCCCGAGCGGGGGATGCCCATCCTTGAGCGCTTCGAGTTTCTCAAGCCCGACGGCGGACTGTG
GCTCGAAACCCCGCAGGAGCGTACTCTTGCGCTACGGTTGCTTGCCGCCCCGGACGAGTATCGTTTTGCGGCCGTCGACC
GGACTCCCCAGCGGCTCACCCAGTACGCCTACGATCTGGCCAGCGACGTGAGCCAGTTCTACGAGCACTGCCCGATTTTG
CCACCTCTGGCGGAGAACCTGGAGCCTGCTTTGCGTTACGCTCGGCTCGGCCTCGTTGTCGCCACGCGGCAGGTGCTGGC
CACTACCCTCACCCTGCTCGGCATCGAGCCGCGCGAATCGATGTAG

Upstream 100 bases:

>100_bases
GGCACTGCGGGGGGCTAAGCCCCCTGGCCGGACCCGCTGCTGTGGCCCTTCCCCCGCATAGGCGTCCTCGCACACCATCT
ACACGATCGGCGGGAAGAGT

Downstream 100 bases:

>100_bases
GCCATGCACCCAGTCTTCCTCGGAACCTTCGCCAGTCTGATCGCCGGCCTCGCCACGGCTGTAGGGGCCTTGCCGGTGCT
CTTTGCCCGCAAGCTCTCCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTALSLQQQLAESIYTALGTAFEAGQLGQLTQLPPRQSVVVEKPKVPEHGDYATPVAMSLAKPCRLAPLAIAEAIASYLA
SDEIGVEVAKPGFINLRLGHRFVAVELQNILELKGDYGRTVPQQPERILLEFVSANPTGPLHLGHGRWAALGSSLERILQ
FAGYTVDSEFYINDAGNQMQLLGLSLKQRYLQVLGEAVELPDGGYKGSYLKELAEQLVADKGDSLGGEPVEWFSAYAEGR
LLEQQKITLQQFRTEFDRWYSERSLHCAGAIEAALADLEARGMLYRAARSRQEQSGEITGRSKKVQAPAAFEEEDGGGEA
LFFKAADFGDEMDRVVKRADGNTTYLAADIAYHWDKYQRGYGRLINIWGADHHGYVPRMKAVAQALGHPADSLEILIGQM
VRLFKTNPETGQKEEMRMSKRRGELVSVDDLIEEVGVDAGRWFLLSQSLNTTVNFDLDLAQSEKFDNPVFYVQYNHARCC
SILRKAPERGMPILERFEFLKPDGGLWLETPQERTLALRLLAAPDEYRFAAVDRTPQRLTQYAYDLASDVSQFYEHCPIL
PPLAENLEPALRYARLGLVVATRQVLATTLTLLGIEPRESM

Sequences:

>Translated_601_residues
MTALSLQQQLAESIYTALGTAFEAGQLGQLTQLPPRQSVVVEKPKVPEHGDYATPVAMSLAKPCRLAPLAIAEAIASYLA
SDEIGVEVAKPGFINLRLGHRFVAVELQNILELKGDYGRTVPQQPERILLEFVSANPTGPLHLGHGRWAALGSSLERILQ
FAGYTVDSEFYINDAGNQMQLLGLSLKQRYLQVLGEAVELPDGGYKGSYLKELAEQLVADKGDSLGGEPVEWFSAYAEGR
LLEQQKITLQQFRTEFDRWYSERSLHCAGAIEAALADLEARGMLYRAARSRQEQSGEITGRSKKVQAPAAFEEEDGGGEA
LFFKAADFGDEMDRVVKRADGNTTYLAADIAYHWDKYQRGYGRLINIWGADHHGYVPRMKAVAQALGHPADSLEILIGQM
VRLFKTNPETGQKEEMRMSKRRGELVSVDDLIEEVGVDAGRWFLLSQSLNTTVNFDLDLAQSEKFDNPVFYVQYNHARCC
SILRKAPERGMPILERFEFLKPDGGLWLETPQERTLALRLLAAPDEYRFAAVDRTPQRLTQYAYDLASDVSQFYEHCPIL
PPLAENLEPALRYARLGLVVATRQVLATTLTLLGIEPRESM
>Mature_600_residues
TALSLQQQLAESIYTALGTAFEAGQLGQLTQLPPRQSVVVEKPKVPEHGDYATPVAMSLAKPCRLAPLAIAEAIASYLAS
DEIGVEVAKPGFINLRLGHRFVAVELQNILELKGDYGRTVPQQPERILLEFVSANPTGPLHLGHGRWAALGSSLERILQF
AGYTVDSEFYINDAGNQMQLLGLSLKQRYLQVLGEAVELPDGGYKGSYLKELAEQLVADKGDSLGGEPVEWFSAYAEGRL
LEQQKITLQQFRTEFDRWYSERSLHCAGAIEAALADLEARGMLYRAARSRQEQSGEITGRSKKVQAPAAFEEEDGGGEAL
FFKAADFGDEMDRVVKRADGNTTYLAADIAYHWDKYQRGYGRLINIWGADHHGYVPRMKAVAQALGHPADSLEILIGQMV
RLFKTNPETGQKEEMRMSKRRGELVSVDDLIEEVGVDAGRWFLLSQSLNTTVNFDLDLAQSEKFDNPVFYVQYNHARCCS
ILRKAPERGMPILERFEFLKPDGGLWLETPQERTLALRLLAAPDEYRFAAVDRTPQRLTQYAYDLASDVSQFYEHCPILP
PLAENLEPALRYARLGLVVATRQVLATTLTLLGIEPRESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=615, Percent_Identity=23.2520325203252, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1788184, Length=593, Percent_Identity=26.9814502529511, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_GLOVI (Q7NDF6)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_927225.1
- ProteinModelPortal:   Q7NDF6
- GeneID:   2602682
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.4279
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   CLSK423190
- BioCyc:   GVIO251221:GLR4279-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 66958; Mature: 66827

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSLQQQLAESIYTALGTAFEAGQLGQLTQLPPRQSVVVEKPKVPEHGDYATPVAMSL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
AKPCRLAPLAIAEAIASYLASDEIGVEVAKPGFINLRLGHRFVAVELQNILELKGDYGRT
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCEEEHHHHHHHHHHCCCCCCC
VPQQPERILLEFVSANPTGPLHLGHGRWAALGSSLERILQFAGYTVDSEFYINDAGNQMQ
CCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
LLGLSLKQRYLQVLGEAVELPDGGYKGSYLKELAEQLVADKGDSLGGEPVEWFSAYAEGR
EHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
LLEQQKITLQQFRTEFDRWYSERSLHCAGAIEAALADLEARGMLYRAARSRQEQSGEITG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RSKKVQAPAAFEEEDGGGEALFFKAADFGDEMDRVVKRADGNTTYLAADIAYHWDKYQRG
CCCEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
YGRLINIWGADHHGYVPRMKAVAQALGHPADSLEILIGQMVRLFKTNPETGQKEEMRMSK
CCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RRGELVSVDDLIEEVGVDAGRWFLLSQSLNTTVNFDLDLAQSEKFDNPVFYVQYNHARCC
HCCCEECHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCHHHH
SILRKAPERGMPILERFEFLKPDGGLWLETPQERTLALRLLAAPDEYRFAAVDRTPQRLT
HHHHHCCCCCCCHHHHHHHHCCCCCEEECCCCHHEEEEEEEECCCCCEEEECCCCHHHHH
QYAYDLASDVSQFYEHCPILPPLAENLEPALRYARLGLVVATRQVLATTLTLLGIEPRES
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
M
C
>Mature Secondary Structure 
TALSLQQQLAESIYTALGTAFEAGQLGQLTQLPPRQSVVVEKPKVPEHGDYATPVAMSL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHH
AKPCRLAPLAIAEAIASYLASDEIGVEVAKPGFINLRLGHRFVAVELQNILELKGDYGRT
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCEEEHHHHHHHHHHCCCCCCC
VPQQPERILLEFVSANPTGPLHLGHGRWAALGSSLERILQFAGYTVDSEFYINDAGNQMQ
CCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEE
LLGLSLKQRYLQVLGEAVELPDGGYKGSYLKELAEQLVADKGDSLGGEPVEWFSAYAEGR
EHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
LLEQQKITLQQFRTEFDRWYSERSLHCAGAIEAALADLEARGMLYRAARSRQEQSGEITG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RSKKVQAPAAFEEEDGGGEALFFKAADFGDEMDRVVKRADGNTTYLAADIAYHWDKYQRG
CCCEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
YGRLINIWGADHHGYVPRMKAVAQALGHPADSLEILIGQMVRLFKTNPETGQKEEMRMSK
CCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RRGELVSVDDLIEEVGVDAGRWFLLSQSLNTTVNFDLDLAQSEKFDNPVFYVQYNHARCC
HCCCEECHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCHHHH
SILRKAPERGMPILERFEFLKPDGGLWLETPQERTLALRLLAAPDEYRFAAVDRTPQRLT
HHHHHCCCCCCCHHHHHHHHCCCCCEEECCCCHHEEEEEEEECCCCCEEEECCCCHHHHH
QYAYDLASDVSQFYEHCPILPPLAENLEPALRYARLGLVVATRQVLATTLTLLGIEPRES
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292