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The map label for this gene is panD2

Identifier: 37523797

GI number: 37523797

Start: 4441744

End: 4442121

Strand: Direct

Name: panD2

Synonym: glr4228

Alternate gene names: 37523797

Gene position: 4441744-4442121 (Clockwise)

Preceding gene: 37523796

Following gene: 37523798

Centisome position: 95.34

GC content: 63.76

Gene sequence:

>378_bases
ATGCTACGCACCGTACTACTCGGCAAAATCCACCGCGCCACTGTGACTGGAGCCTGTCTGGAGTATGTGGGTTCGATCAG
CGTCGACAGCCGTTTGCTCGCGGCGGCGGGTATCCTGCCCCACGAACAGGTGCACGTCGTCAACCTCAACAACGGCGCGC
GCCTGGTCACCTACGCCATCGAGGCCAGCGAAGGTTCCGGGGCGGTGGTCCTCAACGGTGCAGCGGCCCGCTTGGCAGCA
GCCGGCGATCAGGTGATTGTCCTTGCCTACGGCCAGGGCACGGCCGTTGAACTGGAGCACCACCAACCCCAGGTGGTGTA
CGTCGATGCTCAGAACCGCATCGTCTCGGTCCACAGGAGCGTCGAACACGCTGGTTGA

Upstream 100 bases:

>100_bases
CCGAGATCACCGGCTGGCAGGGGGTGGAGGTGGCTCAACAACTGGTGGATAAGGCCATCGCAGCCTACACGCCGTAAACC
AACAAAGGGGGCAGGAGCCA

Downstream 100 bases:

>100_bases
GATCTGGGCCTTTGCGCTGTTGGTGCTCAACAGCCTGGCAGCCCTGTGGCTTTTTACCTACGGGATCAATGCCTACTGGC
TGACTGCCCGGCGCGGGGCG

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase 2

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MLRTVLLGKIHRATVTGACLEYVGSISVDSRLLAAAGILPHEQVHVVNLNNGARLVTYAIEASEGSGAVVLNGAAARLAA
AGDQVIVLAYGQGTAVELEHHQPQVVYVDAQNRIVSVHRSVEHAG

Sequences:

>Translated_125_residues
MLRTVLLGKIHRATVTGACLEYVGSISVDSRLLAAAGILPHEQVHVVNLNNGARLVTYAIEASEGSGAVVLNGAAARLAA
AGDQVIVLAYGQGTAVELEHHQPQVVYVDAQNRIVSVHRSVEHAG
>Mature_125_residues
MLRTVLLGKIHRATVTGACLEYVGSISVDSRLLAAAGILPHEQVHVVNLNNGARLVTYAIEASEGSGAVVLNGAAARLAA
AGDQVIVLAYGQGTAVELEHHQPQVVYVDAQNRIVSVHRSVEHAG

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=121, Percent_Identity=40.495867768595, Blast_Score=95, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND2_GLOVI (Q7NDK7)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_927174.1
- ProteinModelPortal:   Q7NDK7
- SMR:   Q7NDK7
- GeneID:   2602631
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr4228
- NMPDR:   fig|251221.1.peg.4228
- HOGENOM:   HBG302821
- OMA:   CLNGPPA
- ProtClustDB:   PRK05449
- BioCyc:   GVIO251221:GLR4228-MONOMER
- BRENDA:   4.1.1.11
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 13053; Mature: 13053

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTVLLGKIHRATVTGACLEYVGSISVDSRLLAAAGILPHEQVHVVNLNNGARLVTYAI
CCCEEEECCCHHHEEHHHHHHHHCCCCCCCCEEEHHCCCCCCEEEEEEECCCCEEEEEEE
EASEGSGAVVLNGAAARLAAAGDQVIVLAYGQGTAVELEHHQPQVVYVDAQNRIVSVHRS
EECCCCCEEEECCCCEEEECCCCEEEEEEECCCCEEEEECCCCEEEEEECCCEEEEEEHH
VEHAG
HCCCC
>Mature Secondary Structure
MLRTVLLGKIHRATVTGACLEYVGSISVDSRLLAAAGILPHEQVHVVNLNNGARLVTYAI
CCCEEEECCCHHHEEHHHHHHHHCCCCCCCCEEEHHCCCCCCEEEEEEECCCCEEEEEEE
EASEGSGAVVLNGAAARLAAAGDQVIVLAYGQGTAVELEHHQPQVVYVDAQNRIVSVHRS
EECCCCCEEEECCCCEEEECCCCEEEEEEECCCCEEEEECCCCEEEEEECCCEEEEEEHH
VEHAG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292