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The map label for this gene is ppa [H]

Identifier: 37523796

GI number: 37523796

Start: 4441205

End: 4441720

Strand: Direct

Name: ppa [H]

Synonym: glr4227

Alternate gene names: 37523796

Gene position: 4441205-4441720 (Clockwise)

Preceding gene: 37523787

Following gene: 37523797

Centisome position: 95.32

GC content: 56.78

Gene sequence:

>516_bases
GTGATCGACTTGAGTAAGATTCCCGCCCGCCCGAAGGAGGGCCTAATCAACGTTCTGGTGGAAATTCCCGGACGTTCCCA
TAACAAGTTTGAGTTCGACAAGGACCTGGGGATTTTTACCCTCGACCGTGTGCTCTATGCTGCAGTGTACTATCCGGGCG
ATTACGGTTTTGTCCCGAATACGCTGGCGGACGACGGCGATCCGCTCGATGGGCTGGTATTGATGGACGAGCCGACTTTT
ACAGGATGTCTTATCGCTGCGCGGCCGATCGGGGTGCTCGGGATGATCGACAGCGGCGAGGGGGACGAGAAGATTCTCTG
TGTGCCCGTCAAAGATCCGCGCTACGCAGGGGTCAAGGATCTTTCGGACATTGCCCAGCACCGCCTCGACGAGATTGCCG
AATTTTTTGCCACCTACAAACGCCTCGAAAAAAAGGTGACCGAGATCACCGGCTGGCAGGGGGTGGAGGTGGCTCAACAA
CTGGTGGATAAGGCCATCGCAGCCTACACGCCGTAA

Upstream 100 bases:

>100_bases
AAGTGCGGCTGCTCCGTCGTATTGCAACTTCCTTTAGTTTGTCCGTCTCCCCTGGTACGATGCCCTAAAATGGCTATCGG
ACGCATCCGAAGGGGGTATC

Downstream 100 bases:

>100_bases
ACCAACAAAGGGGGCAGGAGCCAATGCTACGCACCGTACTACTCGGCAAAATCCACCGCGCCACTGTGACTGGAGCCTGT
CTGGAGTATGTGGGTTCGAT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MIDLSKIPARPKEGLINVLVEIPGRSHNKFEFDKDLGIFTLDRVLYAAVYYPGDYGFVPNTLADDGDPLDGLVLMDEPTF
TGCLIAARPIGVLGMIDSGEGDEKILCVPVKDPRYAGVKDLSDIAQHRLDEIAEFFATYKRLEKKVTEITGWQGVEVAQQ
LVDKAIAAYTP

Sequences:

>Translated_171_residues
MIDLSKIPARPKEGLINVLVEIPGRSHNKFEFDKDLGIFTLDRVLYAAVYYPGDYGFVPNTLADDGDPLDGLVLMDEPTF
TGCLIAARPIGVLGMIDSGEGDEKILCVPVKDPRYAGVKDLSDIAQHRLDEIAEFFATYKRLEKKVTEITGWQGVEVAQQ
LVDKAIAAYTP
>Mature_171_residues
MIDLSKIPARPKEGLINVLVEIPGRSHNKFEFDKDLGIFTLDRVLYAAVYYPGDYGFVPNTLADDGDPLDGLVLMDEPTF
TGCLIAARPIGVLGMIDSGEGDEKILCVPVKDPRYAGVKDLSDIAQHRLDEIAEFFATYKRLEKKVTEITGWQGVEVAQQ
LVDKAIAAYTP

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=148, Percent_Identity=39.1891891891892, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18845; Mature: 18845

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSKIPARPKEGLINVLVEIPGRSHNKFEFDKDLGIFTLDRVLYAAVYYPGDYGFVPN
CCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TLADDGDPLDGLVLMDEPTFTGCLIAARPIGVLGMIDSGEGDEKILCVPVKDPRYAGVKD
CCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHH
LSDIAQHRLDEIAEFFATYKRLEKKVTEITGWQGVEVAQQLVDKAIAAYTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDLSKIPARPKEGLINVLVEIPGRSHNKFEFDKDLGIFTLDRVLYAAVYYPGDYGFVPN
CCCCCCCCCCCHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TLADDGDPLDGLVLMDEPTFTGCLIAARPIGVLGMIDSGEGDEKILCVPVKDPRYAGVKD
CCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHH
LSDIAQHRLDEIAEFFATYKRLEKKVTEITGWQGVEVAQQLVDKAIAAYTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]