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The map label for this gene is frpA [H]

Identifier: 37523709

GI number: 37523709

Start: 4338985

End: 4340868

Strand: Direct

Name: frpA [H]

Synonym: glr4140

Alternate gene names: 37523709

Gene position: 4338985-4340868 (Clockwise)

Preceding gene: 37523708

Following gene: 37523710

Centisome position: 93.13

GC content: 63.91

Gene sequence:

>1884_bases
ATGCCCGAAGAAGAAGAAGAATTTCACGAAGAAGATGCATCGCCTGGGGAAATGGACGAGCCGGCGATGGCGCTCGAAGC
ACCGGAACCCGAGGAGCCGCAGCTGCTTGCGAGCCTCGAATCCGAGGGGCCGCAGGCGGCCCCGGAAATTCTCAGCGAAC
AGCAGGACGACGACGGCAACACGCTTTTTCGGGAGACCCGCGACGCCGAGGGCGATATCACGGTGCAGGGGGCAAGCTTC
GGCGACGAACTTGTCGTCGAGGCCCACTACGACGACGGATTTCTGGGGCTGGGCATTTTGCGGCAAGTCGACGGCGTCAC
AGTCTCGACCCAATCCGGCTTCAGCAAATCGTACCTGGGCGAGGAAGCTGACAACCTCACCCTCCGGGGAGGAGCCGGAG
GAGATACCTTCGCCATCGACGCGGCGGTCCAGGCCGACCTTACCATCGAAGCCGGCAATGGCAGCGACACGATCCAGGGT
GGCGACGGCAACGAGACCATCGACGGCGGCCGGGGCGATGACACGATCGACGGGGGCGGCGGCGACGACACCATTGCAGG
CGAACGGGGCGACGATCTGATCCGCGGCGGTCTGGGCAATGACACGATCGACGCCGGCGAGGGCAACGACACGATCGACG
GAGGCGACGGCGACGACAAGCTTACCGGCGGCGAAGGGGACGATGTCCTGCACGCCGGGCATGGTCGCGACACCCTCGAA
GACACCCAGGGCAACAACTGGTTTATCGCCCAGGCCCAGGACCGGGTCGCAGCGGCAGATCAAGCCCAAAACGAAACCAC
CACCGCAGCGGATCCGTCGCAGGTGCCCGTCGTCGAGCAGCACAGCTTTGCCCACGGCGCCTACCGCAACTTTGACAACT
GGGATCTCGATGACGACGGCCTGGTAGAAAAGACCGAAACCATCCAGCTGATGAGCGATCCGAGCATCGAGGGCCAGGAT
GCGGCAACCCTGGGCACGTTGCGCTCGATGCAGGGGCAGGCCGACACCTGGAATATCGGCGCATTGAGCGACGACGGCCG
CTTTCCGTGGTCGGAAGACCCTAAAGGAATGAGCCAGGCGGATTTGCTCGCCTACACCCGGCTTGGCGAGGACGACGAGA
ACCGCAAGCTCACCGAAGCTTACTTCCTGCGCACCGACAACTACATCGAAGGACTCAGCGATCAAACCCGTAGCCAGGGG
CTCTTTACCGGCGACGGCACCATCGAGGCGGCCGATGTCAAGCAGGGCAACGCCGGCACCTGCAATCCGCTCTCGGCCCT
GATCGGCGAACTTTCTCAAGATCCCGAGGCGGTTCAGGAGCGCTTTGGGCAAAACGCAGACGGCAGCTTCAGCGTCGAAC
TCGGCAGCGGCGAGCAGAAGGTAGCCCCCCTCACCGACGCCGAGCGCGCCTACTTCGGCCGCGCCGAGAATGGCGACTGG
CAGGCGGTCTACGAAAAAGCCGTCCTGCAGGCGGGCCTGAGCGGCGACGGCAACAACTTCGAAAACACGATCCGCGCCGT
CACCGGCAACGATTCCACTGCGATCACTCTAGACGGCGAACACCGAGCCGAGGCTCTAAGCGCTCTGGAATCGGCCCTCG
AAGACGACCGGCTGGCCCTTGCCAGCCTCAGCGACAACGAGGACGAAAAGCAAAACGGCGGGATTGTCCTGCCGGACAAC
CACGCCTACGCCGTGGTCGGCTACGAAGATGGGCAGGTAGAAATGCAAAATCCCTGGGGCCGCGAGGAACCCAAAGGTGC
GAATGGCCGCCCCCGAGACGGCAAAGACGACGGGCGTTTCACCGTGAGCAAAGACGAACTTATCGACACCTTCGACTGGT
TGGGAGTGGAGCAACCGCCCCGGAGGCCGGGCGGCGGCCGTTAG

Upstream 100 bases:

>100_bases
CCGAACGGCTCTTGGCAGCGATCGACGATTGGCTCGATCGCTGGAACTTGCCCACGCCGGTTTAAACCCTAGTAGCCGGG
CGGTTGTCAGGGAGCGGCAG

Downstream 100 bases:

>100_bases
CTATTTAGGCGGGAAGCCCCGCGCTCTATGCAAAGCATGAGCGTCGGGTACGTCACTACAAAGCAGGTACAAAGCAGCGG
ACACCATCGACGGGTGGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MPEEEEEFHEEDASPGEMDEPAMALEAPEPEEPQLLASLESEGPQAAPEILSEQQDDDGNTLFRETRDAEGDITVQGASF
GDELVVEAHYDDGFLGLGILRQVDGVTVSTQSGFSKSYLGEEADNLTLRGGAGGDTFAIDAAVQADLTIEAGNGSDTIQG
GDGNETIDGGRGDDTIDGGGGDDTIAGERGDDLIRGGLGNDTIDAGEGNDTIDGGDGDDKLTGGEGDDVLHAGHGRDTLE
DTQGNNWFIAQAQDRVAAADQAQNETTTAADPSQVPVVEQHSFAHGAYRNFDNWDLDDDGLVEKTETIQLMSDPSIEGQD
AATLGTLRSMQGQADTWNIGALSDDGRFPWSEDPKGMSQADLLAYTRLGEDDENRKLTEAYFLRTDNYIEGLSDQTRSQG
LFTGDGTIEAADVKQGNAGTCNPLSALIGELSQDPEAVQERFGQNADGSFSVELGSGEQKVAPLTDAERAYFGRAENGDW
QAVYEKAVLQAGLSGDGNNFENTIRAVTGNDSTAITLDGEHRAEALSALESALEDDRLALASLSDNEDEKQNGGIVLPDN
HAYAVVGYEDGQVEMQNPWGREEPKGANGRPRDGKDDGRFTVSKDELIDTFDWLGVEQPPRRPGGGR

Sequences:

>Translated_627_residues
MPEEEEEFHEEDASPGEMDEPAMALEAPEPEEPQLLASLESEGPQAAPEILSEQQDDDGNTLFRETRDAEGDITVQGASF
GDELVVEAHYDDGFLGLGILRQVDGVTVSTQSGFSKSYLGEEADNLTLRGGAGGDTFAIDAAVQADLTIEAGNGSDTIQG
GDGNETIDGGRGDDTIDGGGGDDTIAGERGDDLIRGGLGNDTIDAGEGNDTIDGGDGDDKLTGGEGDDVLHAGHGRDTLE
DTQGNNWFIAQAQDRVAAADQAQNETTTAADPSQVPVVEQHSFAHGAYRNFDNWDLDDDGLVEKTETIQLMSDPSIEGQD
AATLGTLRSMQGQADTWNIGALSDDGRFPWSEDPKGMSQADLLAYTRLGEDDENRKLTEAYFLRTDNYIEGLSDQTRSQG
LFTGDGTIEAADVKQGNAGTCNPLSALIGELSQDPEAVQERFGQNADGSFSVELGSGEQKVAPLTDAERAYFGRAENGDW
QAVYEKAVLQAGLSGDGNNFENTIRAVTGNDSTAITLDGEHRAEALSALESALEDDRLALASLSDNEDEKQNGGIVLPDN
HAYAVVGYEDGQVEMQNPWGREEPKGANGRPRDGKDDGRFTVSKDELIDTFDWLGVEQPPRRPGGGR
>Mature_626_residues
PEEEEEFHEEDASPGEMDEPAMALEAPEPEEPQLLASLESEGPQAAPEILSEQQDDDGNTLFRETRDAEGDITVQGASFG
DELVVEAHYDDGFLGLGILRQVDGVTVSTQSGFSKSYLGEEADNLTLRGGAGGDTFAIDAAVQADLTIEAGNGSDTIQGG
DGNETIDGGRGDDTIDGGGGDDTIAGERGDDLIRGGLGNDTIDAGEGNDTIDGGDGDDKLTGGEGDDVLHAGHGRDTLED
TQGNNWFIAQAQDRVAAADQAQNETTTAADPSQVPVVEQHSFAHGAYRNFDNWDLDDDGLVEKTETIQLMSDPSIEGQDA
ATLGTLRSMQGQADTWNIGALSDDGRFPWSEDPKGMSQADLLAYTRLGEDDENRKLTEAYFLRTDNYIEGLSDQTRSQGL
FTGDGTIEAADVKQGNAGTCNPLSALIGELSQDPEAVQERFGQNADGSFSVELGSGEQKVAPLTDAERAYFGRAENGDWQ
AVYEKAVLQAGLSGDGNNFENTIRAVTGNDSTAITLDGEHRAEALSALESALEDDRLALASLSDNEDEKQNGGIVLPDNH
AYAVVGYEDGQVEMQNPWGREEPKGANGRPRDGKDDGRFTVSKDELIDTFDWLGVEQPPRRPGGGR

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 66665; Mature: 66534

Theoretical pI: Translated: 3.74; Mature: 3.74

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEEEEEFHEEDASPGEMDEPAMALEAPEPEEPQLLASLESEGPQAAPEILSEQQDDDGN
CCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCC
TLFRETRDAEGDITVQGASFGDELVVEAHYDDGFLGLGILRQVDGVTVSTQSGFSKSYLG
CHHHHCCCCCCCEEEECCCCCCEEEEEEECCCCEEHHHHHHHHCCEEEECCCCCCHHHCC
EEADNLTLRGGAGGDTFAIDAAVQADLTIEAGNGSDTIQGGDGNETIDGGRGDDTIDGGG
CCCCCEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCC
GDDTIAGERGDDLIRGGLGNDTIDAGEGNDTIDGGDGDDKLTGGEGDDVLHAGHGRDTLE
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHH
DTQGNNWFIAQAQDRVAAADQAQNETTTAADPSQVPVVEQHSFAHGAYRNFDNWDLDDDG
HCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCCCCCCC
LVEKTETIQLMSDPSIEGQDAATLGTLRSMQGQADTWNIGALSDDGRFPWSEDPKGMSQA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHH
DLLAYTRLGEDDENRKLTEAYFLRTDNYIEGLSDQTRSQGLFTGDGTIEAADVKQGNAGT
HHHHHHHCCCCCCCCEEEEEEEEECCHHHHCCCHHHHHCCEEECCCEEEEECCCCCCCCC
CNPLSALIGELSQDPEAVQERFGQNADGSFSVELGSGEQKVAPLTDAERAYFGRAENGDW
CCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCH
QAVYEKAVLQAGLSGDGNNFENTIRAVTGNDSTAITLDGEHRAEALSALESALEDDRLAL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCEEE
ASLSDNEDEKQNGGIVLPDNHAYAVVGYEDGQVEMQNPWGREEPKGANGRPRDGKDDGRF
EECCCCCCHHCCCCEEEECCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCE
TVSKDELIDTFDWLGVEQPPRRPGGGR
EECHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PEEEEEFHEEDASPGEMDEPAMALEAPEPEEPQLLASLESEGPQAAPEILSEQQDDDGN
CCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCC
TLFRETRDAEGDITVQGASFGDELVVEAHYDDGFLGLGILRQVDGVTVSTQSGFSKSYLG
CHHHHCCCCCCCEEEECCCCCCEEEEEEECCCCEEHHHHHHHHCCEEEECCCCCCHHHCC
EEADNLTLRGGAGGDTFAIDAAVQADLTIEAGNGSDTIQGGDGNETIDGGRGDDTIDGGG
CCCCCEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCC
GDDTIAGERGDDLIRGGLGNDTIDAGEGNDTIDGGDGDDKLTGGEGDDVLHAGHGRDTLE
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHH
DTQGNNWFIAQAQDRVAAADQAQNETTTAADPSQVPVVEQHSFAHGAYRNFDNWDLDDDG
HCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCCCCCCC
LVEKTETIQLMSDPSIEGQDAATLGTLRSMQGQADTWNIGALSDDGRFPWSEDPKGMSQA
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHH
DLLAYTRLGEDDENRKLTEAYFLRTDNYIEGLSDQTRSQGLFTGDGTIEAADVKQGNAGT
HHHHHHHCCCCCCCCEEEEEEEEECCHHHHCCCHHHHHCCEEECCCEEEEECCCCCCCCC
CNPLSALIGELSQDPEAVQERFGQNADGSFSVELGSGEQKVAPLTDAERAYFGRAENGDW
CCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCH
QAVYEKAVLQAGLSGDGNNFENTIRAVTGNDSTAITLDGEHRAEALSALESALEDDRLAL
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCEEE
ASLSDNEDEKQNGGIVLPDNHAYAVVGYEDGQVEMQNPWGREEPKGANGRPRDGKDDGRF
EECCCCCCHHCCCCEEEECCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCE
TVSKDELIDTFDWLGVEQPPRRPGGGR
EECHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8423153 [H]