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The map label for this gene is murQ

Identifier: 37523581

GI number: 37523581

Start: 4214525

End: 4215445

Strand: Direct

Name: murQ

Synonym: glr4012

Alternate gene names: 37523581

Gene position: 4214525-4215445 (Clockwise)

Preceding gene: 37523579

Following gene: 37523584

Centisome position: 90.46

GC content: 66.23

Gene sequence:

>921_bases
ATGGACGAACGGCTGCCCGAGCGCGCGCATCTTGTCACCGAGCAAGTCAATCCCGATAGTGCCCGACTCGACCGGCTCGA
CAGCCCGTCGCTGGTTGAGTTGTTCTGCCGCGAGGACGAGCGGGTGGTGCCGGCCGTGCGGGCTGCCGCGCCCGCCATCG
CCCGGGCGATCGATCTCACCGCTGCCGCCTTGCGCGGCGGGGGGCGTCTGTTTTACGTCGGGGCGGGTACCAGCGGAAGG
CTCGGGGTGCTCGACGCAAGCGAGTGCCCGCCGACTTTTTGTACCGACCCCGAGCAGGTGCAAGGGATCATTGCCGGGGG
AACGGCCGCCCTCACCCGTAGTGTCGAAGGGGCCGAGGACGACCCCGAGGCGGGAGCCGCCGAGCTTGCGGGGCGCGCTC
TGAGTGCTGCGGATGTGGTGGTGGGTATCAGCGCCGGGGGCACTGCTCCCTACGTGAGCGGTGCCCTTGCCTACGCCCGT
TCGCTGGGGGGCGTCACGATCTTCGTAGCCTGTGTACCTACAAACCAGATCCCCGAGCGCTGGGACATCGAAATTCGGGT
GCCGGTGGGGCCGGAGGTGCTCGCCGGTTCGACGCGCCTCAAGGCGGGCACCGCCACCAAGCTGGTGCTCAACATCCTTT
CGACTGGGGCGATGGTTCGCCTCGGCAAGACCTATGGCAACTTGATGGTCGATGTGGCGGTCAGCAACCAGAAGCTGCGT
GACCGGGCCGTGCGCATCCTGACTACCCTCACGGAGCTTGAGCGCACCGCCGCCCTCGCTTTGCTCGAAGCGAGCGGCCT
GCGGGTGAAAGTCGCCTTGCTGATGCACTGGAGCAATCAGGATCCGGCTTCCTGTGCAACTGCTTTGGAAGCGGCGGGTG
GATTGCTTCCTGTTGCTCTTGAGAAATTGAGCGGAAGATAG

Upstream 100 bases:

>100_bases
GTGAAGGCATTGCAAAGCGTCCAGTGATGCCTTTCAGGCGTTGACAAAATGGAGACTATATTTGAGTGTTTACTCCCTGA
AAGTTATAAGGCATCAGGCT

Downstream 100 bases:

>100_bases
GCACTTCTAAAGAGTATCGGGATCGATCCCTTGCTCCCGCAGGTACCGGGCGAGCCTTTCTCGCGATTGCCGTTCGCGTT
CAGCCATCTGGACGGCCTGT

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLTAAALRGGGRLFYVGAGTSGR
LGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAEDDPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYAR
SLGGVTIFVACVPTNQIPERWDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLR
DRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVALEKLSGR

Sequences:

>Translated_306_residues
MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLTAAALRGGGRLFYVGAGTSGR
LGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAEDDPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYAR
SLGGVTIFVACVPTNQIPERWDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLR
DRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVALEKLSGR
>Mature_306_residues
MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLTAAALRGGGRLFYVGAGTSGR
LGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAEDDPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYAR
SLGGVTIFVACVPTNQIPERWDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLR
DRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVALEKLSGR

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=292, Percent_Identity=46.5753424657534, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_GLOVI (Q7NE68)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926958.1
- HSSP:   P44862
- ProteinModelPortal:   Q7NE68
- SMR:   Q7NE68
- GeneID:   2602415
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr4012
- NMPDR:   fig|251221.1.peg.4012
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- BioCyc:   GVIO251221:GLR4012-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- TIGRFAMs:   TIGR00274

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31769; Mature: 31769

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 88-88 ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLT
CCCCCCCHHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAALRGGGRLFYVGAGTSGRLGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAED
HHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHCEEEECCHHHHHHCCCCCCC
DPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYARSLGGVTIFVACVPTNQIPER
CCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
WDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLR
CCEEEECCCCCHHHCCCCEECCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCHHHH
DRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVAL
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHH
EKLSGR
HHHCCC
>Mature Secondary Structure
MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLT
CCCCCCCHHHHHHHCCCCCHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AAALRGGGRLFYVGAGTSGRLGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAED
HHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHCEEEECCHHHHHHCCCCCCC
DPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYARSLGGVTIFVACVPTNQIPER
CCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
WDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLR
CCEEEECCCCCHHHCCCCEECCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCHHHH
DRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVAL
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHH
EKLSGR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292