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The map label for this gene is yciC [H]

Identifier: 37523386

GI number: 37523386

Start: 4023205

End: 4024242

Strand: Direct

Name: yciC [H]

Synonym: glr3817

Alternate gene names: 37523386

Gene position: 4023205-4024242 (Clockwise)

Preceding gene: 37523382

Following gene: 37523387

Centisome position: 86.35

GC content: 59.34

Gene sequence:

>1038_bases
ATGCAGATTCAAGAGCGTGGCCTACCTGTCACGGTAATCACCGGATTTTTGGGCAGCGGCAAGACGACGCTGGTCAACCA
CATCCTGCGCAACAACCAGGGCATCAAAACGGCCGTAATCGTCAACGAATTCGGCGATATCGGCATCGACAGCGAACTGA
TCGTCTCCACCGAAGAAGACATGGTCGAACTGGAGAACGGCTGTATCTGCTGCACCGTCCGCGACGACCTGGTGCAGGCC
ACCCTGCGCATTCTGGAGCGTGATCAAAAAGTCGACTATCTGGTGGTCGAGACCACGGGCCTTGCTGATCCGCTGCCGGT
GGCGATGACGTTTTTGGGTCCCGAACTGCGCAACGTCACCCGCCTCGACGGCATCATCGGCGTCGTGGACGCCGAGAATT
TTGCCCCGACGCTGTTCAATTCCGAGACCGCCGCCAACCAGATCGCCTACTCGGATATTATTTTGCTCAACAAGACCGAC
TGCGTCGAACACGAAGCGCTCGAACGGCTCGAAGGGCAGATCCGCGAACTCAAAGAGGACGGTCCTATCCTGCGCACCGA
ATACGGCCGAGTGGATCTACGCATGATCCTCGATGTGGGCGTCTTCAAGCTCGAAGAGCAATTCGCCGAAGCCGAGACGG
AGGAGCACGGGCACGTCCACGGTCCCGACTGCGGCCACGATCACCACGAGCATGACCACGGGCATAGCCACGACCACCAT
GACCACGATCACGACCATCACCACCACAACCACATCGAGGCGGAAGGCTTTACCTCGATCTCGCTGGTATCCGAGCGGCC
CCTTGCCGCCAAGCAATTCGAGCAGTTCCTCAAAGATCTGCCCCAGGGTGTTTTTCGAGGCAAGGGCATCCTGTGGCTGG
CGGAGTCGCCGGAAAAAGTGATCTTTCACCTGGTGGGCAGCCGCATCCGCATCGACCGCGAAACCTGGGACGGCGCACGC
AAGAATCAGGCGGTCTTCATCGGCAAGGATTTTGACCGCGAGGCGCTCAAGGCCCGCTGGTCGGAGTGTCTGGCTTGA

Upstream 100 bases:

>100_bases
GCGACCCTTTCAGGGTAACCGCCGGGGGCGGTCTGCGAAGCGACGGCGGGCCGGTGCATACTAAAGAGAGGGCGAAGCGA
AGCACCCTGAGGAATCCCAC

Downstream 100 bases:

>100_bases
GGAACCGGGGGATGGCCCTTTCCCTCTGCCTGTGGAGATCGCCCTGATGGACCTGCTGTTACACTGACATCCAAGATCGC
GCGACAAACGGGTTTTGCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MQIQERGLPVTVITGFLGSGKTTLVNHILRNNQGIKTAVIVNEFGDIGIDSELIVSTEEDMVELENGCICCTVRDDLVQA
TLRILERDQKVDYLVVETTGLADPLPVAMTFLGPELRNVTRLDGIIGVVDAENFAPTLFNSETAANQIAYSDIILLNKTD
CVEHEALERLEGQIRELKEDGPILRTEYGRVDLRMILDVGVFKLEEQFAEAETEEHGHVHGPDCGHDHHEHDHGHSHDHH
DHDHDHHHHNHIEAEGFTSISLVSERPLAAKQFEQFLKDLPQGVFRGKGILWLAESPEKVIFHLVGSRIRIDRETWDGAR
KNQAVFIGKDFDREALKARWSECLA

Sequences:

>Translated_345_residues
MQIQERGLPVTVITGFLGSGKTTLVNHILRNNQGIKTAVIVNEFGDIGIDSELIVSTEEDMVELENGCICCTVRDDLVQA
TLRILERDQKVDYLVVETTGLADPLPVAMTFLGPELRNVTRLDGIIGVVDAENFAPTLFNSETAANQIAYSDIILLNKTD
CVEHEALERLEGQIRELKEDGPILRTEYGRVDLRMILDVGVFKLEEQFAEAETEEHGHVHGPDCGHDHHEHDHGHSHDHH
DHDHDHHHHNHIEAEGFTSISLVSERPLAAKQFEQFLKDLPQGVFRGKGILWLAESPEKVIFHLVGSRIRIDRETWDGAR
KNQAVFIGKDFDREALKARWSECLA
>Mature_345_residues
MQIQERGLPVTVITGFLGSGKTTLVNHILRNNQGIKTAVIVNEFGDIGIDSELIVSTEEDMVELENGCICCTVRDDLVQA
TLRILERDQKVDYLVVETTGLADPLPVAMTFLGPELRNVTRLDGIIGVVDAENFAPTLFNSETAANQIAYSDIILLNKTD
CVEHEALERLEGQIRELKEDGPILRTEYGRVDLRMILDVGVFKLEEQFAEAETEEHGHVHGPDCGHDHHEHDHGHSHDHH
DHDHDHHHHNHIEAEGFTSISLVSERPLAAKQFEQFLKDLPQGVFRGKGILWLAESPEKVIFHLVGSRIRIDRETWDGAR
KNQAVFIGKDFDREALKARWSECLA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=362, Percent_Identity=32.3204419889503, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI126722884, Length=362, Percent_Identity=32.0441988950276, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI148727351, Length=362, Percent_Identity=32.0441988950276, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI146231952, Length=348, Percent_Identity=32.7586206896552, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI223941779, Length=202, Percent_Identity=40.5940594059406, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223941776, Length=364, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI119120938, Length=131, Percent_Identity=43.5114503816794, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI87082430, Length=348, Percent_Identity=31.6091954022989, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788499, Length=217, Percent_Identity=33.6405529953917, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324356, Length=225, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38835; Mature: 38835

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIQERGLPVTVITGFLGSGKTTLVNHILRNNQGIKTAVIVNEFGDIGIDSELIVSTEED
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECHHH
MVELENGCICCTVRDDLVQATLRILERDQKVDYLVVETTGLADPLPVAMTFLGPELRNVT
HHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCHHHHHHH
RLDGIIGVVDAENFAPTLFNSETAANQIAYSDIILLNKTDCVEHEALERLEGQIRELKED
HHCCEEEEEECCCCCCCCCCCCHHHHHHEEHEEEEECCCCHHHHHHHHHHHHHHHHHHHC
GPILRTEYGRVDLRMILDVGVFKLEEQFAEAETEEHGHVHGPDCGHDHHEHDHGHSHDHH
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DHDHDHHHHNHIEAEGFTSISLVSERPLAAKQFEQFLKDLPQGVFRGKGILWLAESPEKV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
IFHLVGSRIRIDRETWDGARKNQAVFIGKDFDREALKARWSECLA
HHHHHCCEEEEECHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQIQERGLPVTVITGFLGSGKTTLVNHILRNNQGIKTAVIVNEFGDIGIDSELIVSTEED
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECHHH
MVELENGCICCTVRDDLVQATLRILERDQKVDYLVVETTGLADPLPVAMTFLGPELRNVT
HHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCHHHHHHH
RLDGIIGVVDAENFAPTLFNSETAANQIAYSDIILLNKTDCVEHEALERLEGQIRELKED
HHCCEEEEEECCCCCCCCCCCCHHHHHHEEHEEEEECCCCHHHHHHHHHHHHHHHHHHHC
GPILRTEYGRVDLRMILDVGVFKLEEQFAEAETEEHGHVHGPDCGHDHHEHDHGHSHDHH
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DHDHDHHHHNHIEAEGFTSISLVSERPLAAKQFEQFLKDLPQGVFRGKGILWLAESPEKV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
IFHLVGSRIRIDRETWDGARKNQAVFIGKDFDREALKARWSECLA
HHHHHCCEEEEECHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]