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The map label for this gene is alr [H]

Identifier: 37523387

GI number: 37523387

Start: 4024369

End: 4025514

Strand: Direct

Name: alr [H]

Synonym: glr3818

Alternate gene names: 37523387

Gene position: 4024369-4025514 (Clockwise)

Preceding gene: 37523386

Following gene: 37523388

Centisome position: 86.38

GC content: 68.24

Gene sequence:

>1146_bases
GTGGACGGGTTTGATGCGACGCGACGCGCCTGGGTGGAGATCGACCTCGATGCCCTCAGGCACAATGTTCAACAAATCAG
ACAAAGATTGCGGTCCCATTGCCGGGTGATGGCGGTGGTCAAAGCCGACGCCTACGGCCACGGCGCCCTGAGTGCCGGCC
GCGCCGCCCTGGAGGCGGGGGCCGCCTGCCTGGGGGTGGCCACCCTCGAAGAAGGTGCGCAGTTGCGCGAGAGCGGCCTG
GGTTGTCCGATCGTCGTCCTGGGACCCATCCACACCGGCGCCGAAGTTGCCGCAGTCGAGCACTGGCGGTTGGAACCGAC
GCTTTGCACGCCGCGCCAGGTGCTCGTCTGTGCGGAACACCTGAGTGCTCCCCATCCGGTGCACCTCAAAATCGACACGG
GCATGACCCGCCTGGGCGCACCCTGGCAGGATGCCGTCGAATTTGTGCGCCTGGCCTACCGGCTACCCCGCCTGCAGGTG
GCCTCGGTCTACTCGCACCTGGCCACCGCCGATGAGCCGGACTCCGCCGCCCTGGGCGAGCAACACCGCCGCTTCGAGCG
GGTGCTGGGCGAACTGGAAGCCGCCGGGGTGCGTCCCGAGTGTGTGCACCTGGCCAATTCCGCCGCCGCCCTGGGCGATC
CCGGATTGCACTACGACCTGGTGCGCGTGGGTGTGGCCCTCTACGGCCTCTACCCCGCCCCCGAATTTTATGGAGCCGCC
GAACTGCGGCCGGTGATGCAGGTCAGGGCGCGGGTCACCCAGGTGCGGGAAGTGCCGGCGGACACCGGCGTGAGCTACGG
CCACTTCTGGCGTACCCCGACCCCGAGCCGCCTGGCCACCGTCGCCATCGGCTACGCCGACGGGGTGCCGCGGCGGCTCT
CGGGCCAACTGCAGGTGCTGGTGCACGGGAGACGGGCTCCCCAGGTAGGTGCGATCACCATGGACCAGATCGTCATCGAC
TGCACCCACCTGAGCGCGGTGGAGGAGGGCGATGTGGTGACGCTGCTGGGCCGCGACGGCAACGAAGCAATCGGCGCCGC
CGACTGGGCCGACCCCCTGGGTACCATTGCTTACGAAATTCTTTGCGGTTTTAAGCACCGCCTGCCACGGGTGGTGCGCT
CCACGGCACCGGTATTTAACGTTTAG

Upstream 100 bases:

>100_bases
TGCCTGTGGAGATCGCCCTGATGGACCTGCTGTTACACTGACATCCAAGATCGCGCGACAAACGGGTTTTGCCCGGCGCG
CCAAGGTGGGTGAGTGAGCA

Downstream 100 bases:

>100_bases
CGACCGCCAGTTACCACAAAGAAGGGCATCTTGGCGCTTGTGGTAGCTTTGTTCTACGGTCTGCCGACTGTGGAGCGATA
GAAGACCATGACCTACGATT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDGFDATRRAWVEIDLDALRHNVQQIRQRLRSHCRVMAVVKADAYGHGALSAGRAALEAGAACLGVATLEEGAQLRESGL
GCPIVVLGPIHTGAEVAAVEHWRLEPTLCTPRQVLVCAEHLSAPHPVHLKIDTGMTRLGAPWQDAVEFVRLAYRLPRLQV
ASVYSHLATADEPDSAALGEQHRRFERVLGELEAAGVRPECVHLANSAAALGDPGLHYDLVRVGVALYGLYPAPEFYGAA
ELRPVMQVRARVTQVREVPADTGVSYGHFWRTPTPSRLATVAIGYADGVPRRLSGQLQVLVHGRRAPQVGAITMDQIVID
CTHLSAVEEGDVVTLLGRDGNEAIGAADWADPLGTIAYEILCGFKHRLPRVVRSTAPVFNV

Sequences:

>Translated_381_residues
MDGFDATRRAWVEIDLDALRHNVQQIRQRLRSHCRVMAVVKADAYGHGALSAGRAALEAGAACLGVATLEEGAQLRESGL
GCPIVVLGPIHTGAEVAAVEHWRLEPTLCTPRQVLVCAEHLSAPHPVHLKIDTGMTRLGAPWQDAVEFVRLAYRLPRLQV
ASVYSHLATADEPDSAALGEQHRRFERVLGELEAAGVRPECVHLANSAAALGDPGLHYDLVRVGVALYGLYPAPEFYGAA
ELRPVMQVRARVTQVREVPADTGVSYGHFWRTPTPSRLATVAIGYADGVPRRLSGQLQVLVHGRRAPQVGAITMDQIVID
CTHLSAVEEGDVVTLLGRDGNEAIGAADWADPLGTIAYEILCGFKHRLPRVVRSTAPVFNV
>Mature_381_residues
MDGFDATRRAWVEIDLDALRHNVQQIRQRLRSHCRVMAVVKADAYGHGALSAGRAALEAGAACLGVATLEEGAQLRESGL
GCPIVVLGPIHTGAEVAAVEHWRLEPTLCTPRQVLVCAEHLSAPHPVHLKIDTGMTRLGAPWQDAVEFVRLAYRLPRLQV
ASVYSHLATADEPDSAALGEQHRRFERVLGELEAAGVRPECVHLANSAAALGDPGLHYDLVRVGVALYGLYPAPEFYGAA
ELRPVMQVRARVTQVREVPADTGVSYGHFWRTPTPSRLATVAIGYADGVPRRLSGQLQVLVHGRRAPQVGAITMDQIVID
CTHLSAVEEGDVVTLLGRDGNEAIGAADWADPLGTIAYEILCGFKHRLPRVVRSTAPVFNV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=363, Percent_Identity=33.8842975206612, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1787439, Length=370, Percent_Identity=31.8918918918919, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41161; Mature: 41161

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGFDATRRAWVEIDLDALRHNVQQIRQRLRSHCRVMAVVKADAYGHGALSAGRAALEAG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHC
AACLGVATLEEGAQLRESGLGCPIVVLGPIHTGAEVAAVEHWRLEPTLCTPRQVLVCAEH
CHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCCCHHHHHHHHH
LSAPHPVHLKIDTGMTRLGAPWQDAVEFVRLAYRLPRLQVASVYSHLATADEPDSAALGE
CCCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHH
QHRRFERVLGELEAAGVRPECVHLANSAAALGDPGLHYDLVRVGVALYGLYPAPEFYGAA
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCHH
ELRPVMQVRARVTQVREVPADTGVSYGHFWRTPTPSRLATVAIGYADGVPRRLSGQLQVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHCCCEEEE
VHGRRAPQVGAITMDQIVIDCTHLSAVEEGDVVTLLGRDGNEAIGAADWADPLGTIAYEI
EECCCCCCCCCEEHHHHEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHH
LCGFKHRLPRVVRSTAPVFNV
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDGFDATRRAWVEIDLDALRHNVQQIRQRLRSHCRVMAVVKADAYGHGALSAGRAALEAG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHC
AACLGVATLEEGAQLRESGLGCPIVVLGPIHTGAEVAAVEHWRLEPTLCTPRQVLVCAEH
CHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHEECCCCCCCCHHHHHHHHH
LSAPHPVHLKIDTGMTRLGAPWQDAVEFVRLAYRLPRLQVASVYSHLATADEPDSAALGE
CCCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHH
QHRRFERVLGELEAAGVRPECVHLANSAAALGDPGLHYDLVRVGVALYGLYPAPEFYGAA
HHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCHH
ELRPVMQVRARVTQVREVPADTGVSYGHFWRTPTPSRLATVAIGYADGVPRRLSGQLQVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHCCCEEEE
VHGRRAPQVGAITMDQIVIDCTHLSAVEEGDVVTLLGRDGNEAIGAADWADPLGTIAYEI
EECCCCCCCCCEEHHHHEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHH
LCGFKHRLPRVVRSTAPVFNV
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]