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The map label for this gene is btuB [H]

Identifier: 37523249

GI number: 37523249

Start: 3887007

End: 3889238

Strand: Reverse

Name: btuB [H]

Synonym: gll3680

Alternate gene names: 37523249

Gene position: 3889238-3887007 (Counterclockwise)

Preceding gene: 37523250

Following gene: 37523246

Centisome position: 83.48

GC content: 59.9

Gene sequence:

>2232_bases
ATGTCCGGGCTGCGCGTGGGCGGACTGGTTTTGGGTTGCGCGTTTTCGGTTTCGATTGCGGCGGCGGCCGAACCTCTGCC
GCCTGTCTCCACGCGGGCGGGCGACCTGGCCCCGGCTGAATGGAACCGCATTGCCCAGGCGGCCGGGTCACAGGTTGCTC
CTTCTCAGCCGGTGGCCCAGCAGGCGGGCGAGACCGAAGCGGACCTCAAGGATGAACCCATCGATCTCGACGAGGTGACC
GTCACCGGCACCGGTCGAGCCCGGCGGCAGAGCGAGACGACCACGCCAATTTATATCATCGACCAAAAAGAAATCGAGCA
AAAAGGCTCGCGCACCCTGGGAGATGCGATCCGCAACGTGCCGGGGGTGACCACCAACATCTTCGGAGCCGGCTCGGATG
TCCACAACGGCTACTTTATCCGCGGCGTGCCCACCACCAGCACGGCCATCCTCATCGACGGCCGTCCGATCACCAACCTC
AACCAGGAACACTACGATCCGAGCGAGATTCCCGTCAATAATGTCGAGCGCATCGAGGTGATGCCTTCCGGGGGAACGAC
CCTCTACGGCAGCACGGCCCTGGGCGGCGTCATCAACGTGATCACCCGCAAGCCCACCCGGCCCATCGAAGGGCAGTTGT
CCGTGGAATTTGGCTCCTACGGCTACAGCAAGTACGGCGCCTACTACCAGGGCAAAAGCGGACCGGTTACCTACAATTTC
AACTACGAGAACTTCAATACCCTCAACAGCTTTTTCTACCGGGTGGAGCGGCCGGTGGGCATCTTGAGCGGTACCCGGCC
CAACGGCGATGTCAATATGCGCTCCTACAACCTCGATGTCGGCTACGAAATCGACGCGCGCAACACGATCACCCTCAACA
CCTACTTGCGCAATTTCGCTAAGGGCATCTCGCCATTTTCGATCGTCGATACCCGTCAGAACGTCTTTGGCGGCCAAAGT
GCCGAGCAACTCGGGCTCAACGCCGATCACCAATCGCGTTTGCTCACCGACACCTGGGGTATCGGCCTCACCTGGGACAG
CAAACTCGGTCAGGGCAACGATTCGAACCTGCAATTCCGCGTCTCGGTGGACCGGGCGCTCAACCGTGAACTCGACCGCA
TCGGCGACGATTTCAGCACCGAGATTTATCTATTGGGACTGCGCGGCAGCCACGCCTGGCAGGTTTCTCCCGGCTGGGGC
ATTACCTACGGCTTTGACTTCCTGCGCGAAATCGGCCGCTCCGGGGTGACGACGATTGCGACGGGAACCAGCACCACCGA
TTACGATACCAGCCTCGACCGGCCCGCCCTGTTTTTCCTCAACGACTTCAAGCTGGCGAGCAACGTCACACTCACCGCCG
GGGCTAGGTACAGCATCACCAGCCAGTTCGGCAATTCCTTTGATCCCAACATCGGCATCCGCTGGCAAGTCGCTCCCAAC
TTCGCCCTGCGCACCAACTTCAATCAGGGATTCAAAGCGCCCAACTTTCACGATCTTTACGGCAAAACCGTCCACAAGGG
CAACCCGAACCTGCTGCCTGAGCGCGGTTCATTTTTTGACGCCGGCATCGATTGGCAACCAACACCCACCACCAACTTGC
GCTTTACGACCTTCATCGCCAACATCAGCAACTTGATGTCCCTCAACCTGGCAGACCCGCGCTTCGCGGATTTTGCCTAT
TTCCAGTCGCTGGGCTATATCTTCAACGACCGGGTGCGGGTCAATTATCCGTCGGTTTACAACACCGGCTTCGAGATGGG
TTTCAACTGGCGGATGGCTCCGAGTTGGGAATTCTTTTTGACCAATACCTACACCGACTCGCGGGTCGTAGAGGGGTTGC
GGCCTGAGATCAACCAGACTCAACAGGCGCTGGTGCCCTTTTTGATGGGCCGTGCCGGATTCAGCTACGAAGATCCGAAC
GGCTTTCGCGCGGCTGTCTTTGCCAACGTCGTAGGCGGTCGCTCGGTGGACACCTACCACGTCGGGCCGGGGGATGCCGA
GGCGTTCGACCCCGCCGGCAATCCGATATTTATCTCCCATATCGCCAAATTGCCGCCCGGCTCGCTGCTGCCCGGCTACA
CGACTGTGGATCTGTCGCTTCGGGTACCTGTGGCCCAGGCCATCGTCTTGAACGCCTATATCGACAATCTGCTCAACACC
TATTACGAGCGCTCCTACGGCGGTCCCGCCCCCGGCACCAATTTCCGGGTGGGCTTGAAGACGACTTTTTGA

Upstream 100 bases:

>100_bases
TAAAATCTTTCTTAAAGTTGTTCATCTTTCTTGACAAAGATCCGCCGCCCGGGGTGGGGTGAACGGCGGGTTATTAGATC
CAAACAGATAGGGAGAGTGT

Downstream 100 bases:

>100_bases
TGGCGGCAGGGCCGCTATTCGGTGTCGTATCGAATCCGGGTGAAGCGGCAGGGTTTGAATCGGACACAGTCTTTTTGGCC
GCTCTTTGGTTTGGGATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MSGLRVGGLVLGCAFSVSIAAAAEPLPPVSTRAGDLAPAEWNRIAQAAGSQVAPSQPVAQQAGETEADLKDEPIDLDEVT
VTGTGRARRQSETTTPIYIIDQKEIEQKGSRTLGDAIRNVPGVTTNIFGAGSDVHNGYFIRGVPTTSTAILIDGRPITNL
NQEHYDPSEIPVNNVERIEVMPSGGTTLYGSTALGGVINVITRKPTRPIEGQLSVEFGSYGYSKYGAYYQGKSGPVTYNF
NYENFNTLNSFFYRVERPVGILSGTRPNGDVNMRSYNLDVGYEIDARNTITLNTYLRNFAKGISPFSIVDTRQNVFGGQS
AEQLGLNADHQSRLLTDTWGIGLTWDSKLGQGNDSNLQFRVSVDRALNRELDRIGDDFSTEIYLLGLRGSHAWQVSPGWG
ITYGFDFLREIGRSGVTTIATGTSTTDYDTSLDRPALFFLNDFKLASNVTLTAGARYSITSQFGNSFDPNIGIRWQVAPN
FALRTNFNQGFKAPNFHDLYGKTVHKGNPNLLPERGSFFDAGIDWQPTPTTNLRFTTFIANISNLMSLNLADPRFADFAY
FQSLGYIFNDRVRVNYPSVYNTGFEMGFNWRMAPSWEFFLTNTYTDSRVVEGLRPEINQTQQALVPFLMGRAGFSYEDPN
GFRAAVFANVVGGRSVDTYHVGPGDAEAFDPAGNPIFISHIAKLPPGSLLPGYTTVDLSLRVPVAQAIVLNAYIDNLLNT
YYERSYGGPAPGTNFRVGLKTTF

Sequences:

>Translated_743_residues
MSGLRVGGLVLGCAFSVSIAAAAEPLPPVSTRAGDLAPAEWNRIAQAAGSQVAPSQPVAQQAGETEADLKDEPIDLDEVT
VTGTGRARRQSETTTPIYIIDQKEIEQKGSRTLGDAIRNVPGVTTNIFGAGSDVHNGYFIRGVPTTSTAILIDGRPITNL
NQEHYDPSEIPVNNVERIEVMPSGGTTLYGSTALGGVINVITRKPTRPIEGQLSVEFGSYGYSKYGAYYQGKSGPVTYNF
NYENFNTLNSFFYRVERPVGILSGTRPNGDVNMRSYNLDVGYEIDARNTITLNTYLRNFAKGISPFSIVDTRQNVFGGQS
AEQLGLNADHQSRLLTDTWGIGLTWDSKLGQGNDSNLQFRVSVDRALNRELDRIGDDFSTEIYLLGLRGSHAWQVSPGWG
ITYGFDFLREIGRSGVTTIATGTSTTDYDTSLDRPALFFLNDFKLASNVTLTAGARYSITSQFGNSFDPNIGIRWQVAPN
FALRTNFNQGFKAPNFHDLYGKTVHKGNPNLLPERGSFFDAGIDWQPTPTTNLRFTTFIANISNLMSLNLADPRFADFAY
FQSLGYIFNDRVRVNYPSVYNTGFEMGFNWRMAPSWEFFLTNTYTDSRVVEGLRPEINQTQQALVPFLMGRAGFSYEDPN
GFRAAVFANVVGGRSVDTYHVGPGDAEAFDPAGNPIFISHIAKLPPGSLLPGYTTVDLSLRVPVAQAIVLNAYIDNLLNT
YYERSYGGPAPGTNFRVGLKTTF
>Mature_742_residues
SGLRVGGLVLGCAFSVSIAAAAEPLPPVSTRAGDLAPAEWNRIAQAAGSQVAPSQPVAQQAGETEADLKDEPIDLDEVTV
TGTGRARRQSETTTPIYIIDQKEIEQKGSRTLGDAIRNVPGVTTNIFGAGSDVHNGYFIRGVPTTSTAILIDGRPITNLN
QEHYDPSEIPVNNVERIEVMPSGGTTLYGSTALGGVINVITRKPTRPIEGQLSVEFGSYGYSKYGAYYQGKSGPVTYNFN
YENFNTLNSFFYRVERPVGILSGTRPNGDVNMRSYNLDVGYEIDARNTITLNTYLRNFAKGISPFSIVDTRQNVFGGQSA
EQLGLNADHQSRLLTDTWGIGLTWDSKLGQGNDSNLQFRVSVDRALNRELDRIGDDFSTEIYLLGLRGSHAWQVSPGWGI
TYGFDFLREIGRSGVTTIATGTSTTDYDTSLDRPALFFLNDFKLASNVTLTAGARYSITSQFGNSFDPNIGIRWQVAPNF
ALRTNFNQGFKAPNFHDLYGKTVHKGNPNLLPERGSFFDAGIDWQPTPTTNLRFTTFIANISNLMSLNLADPRFADFAYF
QSLGYIFNDRVRVNYPSVYNTGFEMGFNWRMAPSWEFFLTNTYTDSRVVEGLRPEINQTQQALVPFLMGRAGFSYEDPNG
FRAAVFANVVGGRSVDTYHVGPGDAEAFDPAGNPIFISHIAKLPPGSLLPGYTTVDLSLRVPVAQAIVLNAYIDNLLNTY
YERSYGGPAPGTNFRVGLKTTF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=172, Percent_Identity=33.7209302325581, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790405, Length=163, Percent_Identity=30.6748466257669, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81461; Mature: 81330

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLRVGGLVLGCAFSVSIAAAAEPLPPVSTRAGDLAPAEWNRIAQAAGSQVAPSQPVAQ
CCCCEECCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
QAGETEADLKDEPIDLDEVTVTGTGRARRQSETTTPIYIIDQKEIEQKGSRTLGDAIRNV
HCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHC
PGVTTNIFGAGSDVHNGYFIRGVPTTSTAILIDGRPITNLNQEHYDPSEIPVNNVERIEV
CCCEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
MPSGGTTLYGSTALGGVINVITRKPTRPIEGQLSVEFGSYGYSKYGAYYQGKSGPVTYNF
ECCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHCCCEEECCCCCEEEEE
NYENFNTLNSFFYRVERPVGILSGTRPNGDVNMRSYNLDVGYEIDARNTITLNTYLRNFA
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECEECEEECCCCEEEHHHHHHHHH
KGISPFSIVDTRQNVFGGQSAEQLGLNADHQSRLLTDTWGIGLTWDSKLGQGNDSNLQFR
HCCCCEEEEECHHHHCCCCCHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEE
VSVDRALNRELDRIGDDFSTEIYLLGLRGSHAWQVSPGWGITYGFDFLREIGRSGVTTIA
EEHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEE
TGTSTTDYDTSLDRPALFFLNDFKLASNVTLTAGARYSITSQFGNSFDPNIGIRWQVAPN
ECCCCCCCCCCCCCCEEEEEECEEEECCEEEECCCCEEEHHHCCCCCCCCCCEEEEECCC
FALRTNFNQGFKAPNFHDLYGKTVHKGNPNLLPERGSFFDAGIDWQPTPTTNLRFTTFIA
EEEECCCCCCCCCCCCHHHCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCEEEEHHHH
NISNLMSLNLADPRFADFAYFQSLGYIFNDRVRVNYPSVYNTGFEMGFNWRMAPSWEFFL
HHHHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCEEEEE
TNTYTDSRVVEGLRPEINQTQQALVPFLMGRAGFSYEDPNGFRAAVFANVVGGRSVDTYH
EECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCEEEE
VGPGDAEAFDPAGNPIFISHIAKLPPGSLLPGYTTVDLSLRVPVAQAIVLNAYIDNLLNT
CCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHH
YYERSYGGPAPGTNFRVGLKTTF
HHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SGLRVGGLVLGCAFSVSIAAAAEPLPPVSTRAGDLAPAEWNRIAQAAGSQVAPSQPVAQ
CCCEECCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHH
QAGETEADLKDEPIDLDEVTVTGTGRARRQSETTTPIYIIDQKEIEQKGSRTLGDAIRNV
HCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHCCHHHHHHHHHC
PGVTTNIFGAGSDVHNGYFIRGVPTTSTAILIDGRPITNLNQEHYDPSEIPVNNVERIEV
CCCEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
MPSGGTTLYGSTALGGVINVITRKPTRPIEGQLSVEFGSYGYSKYGAYYQGKSGPVTYNF
ECCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHCCCEEECCCCCEEEEE
NYENFNTLNSFFYRVERPVGILSGTRPNGDVNMRSYNLDVGYEIDARNTITLNTYLRNFA
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECEECEEECCCCEEEHHHHHHHHH
KGISPFSIVDTRQNVFGGQSAEQLGLNADHQSRLLTDTWGIGLTWDSKLGQGNDSNLQFR
HCCCCEEEEECHHHHCCCCCHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEE
VSVDRALNRELDRIGDDFSTEIYLLGLRGSHAWQVSPGWGITYGFDFLREIGRSGVTTIA
EEHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEE
TGTSTTDYDTSLDRPALFFLNDFKLASNVTLTAGARYSITSQFGNSFDPNIGIRWQVAPN
ECCCCCCCCCCCCCCEEEEEECEEEECCEEEECCCCEEEHHHCCCCCCCCCCEEEEECCC
FALRTNFNQGFKAPNFHDLYGKTVHKGNPNLLPERGSFFDAGIDWQPTPTTNLRFTTFIA
EEEECCCCCCCCCCCCHHHCCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCEEEEHHHH
NISNLMSLNLADPRFADFAYFQSLGYIFNDRVRVNYPSVYNTGFEMGFNWRMAPSWEFFL
HHHHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCEEEEE
TNTYTDSRVVEGLRPEINQTQQALVPFLMGRAGFSYEDPNGFRAAVFANVVGGRSVDTYH
EECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHCCCCCEEEE
VGPGDAEAFDPAGNPIFISHIAKLPPGSLLPGYTTVDLSLRVPVAQAIVLNAYIDNLLNT
CCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHH
YYERSYGGPAPGTNFRVGLKTTF
HHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA