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The map label for this gene is bioH [C]

Identifier: 37523246

GI number: 37523246

Start: 3883181

End: 3884230

Strand: Reverse

Name: bioH [C]

Synonym: gll3677

Alternate gene names: 37523246

Gene position: 3884230-3883181 (Counterclockwise)

Preceding gene: 37523249

Following gene: 37523245

Centisome position: 83.37

GC content: 66.67

Gene sequence:

>1050_bases
GTGATCACAGTGTCGAAATATTCGTTGCCCATCGCCGATTCTCCCAGCCCAGAGCGCCATCCTAGCTTCCGGCTTCCCCC
ACGCCGCAGCCCGTGGACGGGTAGAATCAGAAATAAATCTTCACGACCGACAGGAGCCCGGATGCGCGCCGATCTCAAGC
CCCCCTCGACCACCGAAGCGTACTGGACCTGGCGGGGCCATCGCATCTGCTACTGGGTGGCCGAGCCGAATGCCGCCCCT
GAGCGCCCGCCGATCGTGCTGTTGCACGGCTTTGGCGCCTCGGCGGGCCATTGGCGCAAAAATATTGCCGAACTGGCGGC
CCACCGCCGGGTCTATGCCCTCGACTGGCTGGGTTTCGGCGCTTCGGCCAAACCGGCCCTTCCTTACAGTCTGGAGCTGT
GGGAGGCACAACTGGTCGATTTTTGCACTGAGGTGGTCGGTGCCCCGGCGGTGCTGGTCGGCAATTCGATCGGCGCCCTC
GAAGCGCTGATGGTCACCGCCCGCCACCCCGAGCGGGCGACGGCCACGGTGCTGCTCAACTGTGCAGGCGGGCTCACCCA
CCGCCCCGAGGAACTGCCGCTGGTCACCCGGCCGGTGATGGCGGCGATGCAGATGGTCCTGCGCGTGCCCGGTCTTGCCG
AGCGCTTTTTTGATTTCGCCCGCTCCAAACGCAACATCCGCAACACCCTGCGCCAGGTCTACGGCAACGCCGAGGCGGTC
ACCGAAGAACTGGTCGAACTGCTGTACACTCCCTCGAGCGATCCGGGTGCCGCCGCCGTGTTCGTCTCGGTGCTCACCGC
CGAGGCCGGCCCCCGTCCCGAAGAACTGCTGCCCCTGGTGCGCACGCCCCTACTGGTCCTCTGGGGCGACAAAGACCCCT
GGACACCTATCGGCCGCGGTCGCACCTTCGCCCGCTACGCCCCCCAGTCCCAGTTCGTGGCCCTCGAAGGTCTTGGCCAC
TGCCCCCACGACGAGGACCCCCGGCGGGTCAATGCCGCTATCCGCGAGTGGCTGGCGACCACCGAGTGCCTACATGACAA
TCGGGCGTGA

Upstream 100 bases:

>100_bases
CAGCTGCTCCAGATAGGCGTCGAACTCGCCCCCCATCTCCAGCAATACCGGCTTGAGCAGGTGGGCAATGGCCTCTGGGG
AACGGGCCGAGCGCGCCCGG

Downstream 100 bases:

>100_bases
AATTGAGACGGTTATTGCAGAAATGTCTTTTTTTCCGATGCGACCGCTGAGCGTCCGGGGCAGTTGTAGGGTGCTGTCCA
GCCGAAACTTCGGGGCTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MITVSKYSLPIADSPSPERHPSFRLPPRRSPWTGRIRNKSSRPTGARMRADLKPPSTTEAYWTWRGHRICYWVAEPNAAP
ERPPIVLLHGFGASAGHWRKNIAELAAHRRVYALDWLGFGASAKPALPYSLELWEAQLVDFCTEVVGAPAVLVGNSIGAL
EALMVTARHPERATATVLLNCAGGLTHRPEELPLVTRPVMAAMQMVLRVPGLAERFFDFARSKRNIRNTLRQVYGNAEAV
TEELVELLYTPSSDPGAAAVFVSVLTAEAGPRPEELLPLVRTPLLVLWGDKDPWTPIGRGRTFARYAPQSQFVALEGLGH
CPHDEDPRRVNAAIREWLATTECLHDNRA

Sequences:

>Translated_349_residues
MITVSKYSLPIADSPSPERHPSFRLPPRRSPWTGRIRNKSSRPTGARMRADLKPPSTTEAYWTWRGHRICYWVAEPNAAP
ERPPIVLLHGFGASAGHWRKNIAELAAHRRVYALDWLGFGASAKPALPYSLELWEAQLVDFCTEVVGAPAVLVGNSIGAL
EALMVTARHPERATATVLLNCAGGLTHRPEELPLVTRPVMAAMQMVLRVPGLAERFFDFARSKRNIRNTLRQVYGNAEAV
TEELVELLYTPSSDPGAAAVFVSVLTAEAGPRPEELLPLVRTPLLVLWGDKDPWTPIGRGRTFARYAPQSQFVALEGLGH
CPHDEDPRRVNAAIREWLATTECLHDNRA
>Mature_349_residues
MITVSKYSLPIADSPSPERHPSFRLPPRRSPWTGRIRNKSSRPTGARMRADLKPPSTTEAYWTWRGHRICYWVAEPNAAP
ERPPIVLLHGFGASAGHWRKNIAELAAHRRVYALDWLGFGASAKPALPYSLELWEAQLVDFCTEVVGAPAVLVGNSIGAL
EALMVTARHPERATATVLLNCAGGLTHRPEELPLVTRPVMAAMQMVLRVPGLAERFFDFARSKRNIRNTLRQVYGNAEAV
TEELVELLYTPSSDPGAAAVFVSVLTAEAGPRPEELLPLVRTPLLVLWGDKDPWTPIGRGRTFARYAPQSQFVALEGLGH
CPHDEDPRRVNAAIREWLATTECLHDNRA

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=282, Percent_Identity=25.886524822695, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586387, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24586391, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24586389, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24586385, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 38690; Mature: 38690

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVSKYSLPIADSPSPERHPSFRLPPRRSPWTGRIRNKSSRPTGARMRADLKPPSTTEA
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCE
YWTWRGHRICYWVAEPNAAPERPPIVLLHGFGASAGHWRKNIAELAAHRRVYALDWLGFG
EEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCC
ASAKPALPYSLELWEAQLVDFCTEVVGAPAVLVGNSIGALEALMVTARHPERATATVLLN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCEEEEEEE
CAGGLTHRPEELPLVTRPVMAAMQMVLRVPGLAERFFDFARSKRNIRNTLRQVYGNAEAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TEELVELLYTPSSDPGAAAVFVSVLTAEAGPRPEELLPLVRTPLLVLWGDKDPWTPIGRG
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
RTFARYAPQSQFVALEGLGHCPHDEDPRRVNAAIREWLATTECLHDNRA
CCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MITVSKYSLPIADSPSPERHPSFRLPPRRSPWTGRIRNKSSRPTGARMRADLKPPSTTEA
CEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCE
YWTWRGHRICYWVAEPNAAPERPPIVLLHGFGASAGHWRKNIAELAAHRRVYALDWLGFG
EEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCC
ASAKPALPYSLELWEAQLVDFCTEVVGAPAVLVGNSIGALEALMVTARHPERATATVLLN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCEEEEEEE
CAGGLTHRPEELPLVTRPVMAAMQMVLRVPGLAERFFDFARSKRNIRNTLRQVYGNAEAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TEELVELLYTPSSDPGAAAVFVSVLTAEAGPRPEELLPLVRTPLLVLWGDKDPWTPIGRG
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
RTFARYAPQSQFVALEGLGHCPHDEDPRRVNAAIREWLATTECLHDNRA
CCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]