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The map label for this gene is czcC [H]

Identifier: 37523187

GI number: 37523187

Start: 3814312

End: 3815619

Strand: Direct

Name: czcC [H]

Synonym: glr3618

Alternate gene names: 37523187

Gene position: 3814312-3815619 (Clockwise)

Preceding gene: 37523182

Following gene: 37523192

Centisome position: 81.87

GC content: 66.59

Gene sequence:

>1308_bases
ATGCATTACCGTCTGTATTTGAGCGGCATCGCTTTGCTGTGGGCCGGGATGAACGCCCTGCCCGCCAATGCCCAGGGCGT
CCTGCCCGCAGGCGGACCCCTTGGGCTCAGACAGGCGCTCAGCCAGGCAGAACTGCGCAACCCGCAGCTGGTGGTTGCCC
AGCGCAACCTGGGCATTGGGCTAGCCGGGATCACCGCCGCCGGGGCTGCTCCGAACCCGCAACTGACCGTCTACTGGGGG
TTCGGCACGGTCTACACCGAGGACGGCAGCCCCCAGACAGTGGGGCTTTCTCAGAAACTGGAGACGGCAGGCAAGCGGCC
GGCCCGCCTTGCCCTGGCCGACGCCCAGTACCGCCTCGCCCTTTTACAGTACAACGCCACACGCTTTGAAATCCGCTCGC
AGGTGCGCAAAGCCTACGCCCAGTTCGCCGCGGCCCAGGCCGGCGGCCGCGCCCTCGAAGTGCAGGAGCGCCTCGCCCAA
AGGCTGCTCGAAGTAGCCCGCAAGCGCAGCGCAGCGGGCGAATCGCCCAAAACCGACGCCCTGCAGACCCAACTGGAGGT
CAACCGGCTCAAAACCCAACAGACCGAAGCCCTCGGCCGCGTCGAGCAGGCGCAGATCGCCCTGAGTGGTCTGTTGGGAC
GCGATCCGGAAGAAACCCTCGATATCGACGATCTGGGTCTATTTGAGCTGTCGCTCGAAAAAACTGCCCTGGTTCCTTTG
CCGGGCGCCCCCGTGCCGCTGGTGGCCACCTTCCTGGAGCGGGCTTACCGCGCCCGCTTAGATCTGCAGGCGGCCGAGCA
GCAGCGGGAGGTGGCCCGCCGCCAGCTGGCTCTGGCCCGCGCCCAGCGCGTCCCGGATGTGAATGTGGCGACTGGGTATC
TGTTTACCACGCGCACCAACAGCGACCCCCAGGCCCAGGGGGTCTACGTGGGCGTGGGGATCGATCTGCCGGTCTTCTAC
AACAACCAGGGCGAAGTGAAACTGGCGGAACTGGCCGGCGAGCAAAGCAGCCTGCAGATCGATGCTCTGAAGCTGCAGAT
TGCCGTGGAAGTGCGCACGGCCTACCGGGCGCTGCTCAACGCCCGCGAGAGCCTGCGCCGCCACCGCAACCAGCTGTTGC
CCGCCGCCCAGGACGTGGTACAGCTGACCCAACTGAGTTACGAACTGGGCAAGCGCGACCTGGGCGAGGTGGTCCTCGCC
CAGCAGGCGGCCCAGGCGGTGCTCGAAAGCTATCTCGAAGCAGTGGTGGCCTACCAGGGCGCCTGGGCGGATCTCGAAAA
AGCGGTGGGCGAACCGCTCGATGTCTAG

Upstream 100 bases:

>100_bases
TATCAGCCGCGCAACCGCCACAGCAGTCGTCCATGCGACGCTTCCCAACCGGGCTGTGCGGAGAAGATGAACCTCAATCA
CTTCAGCAGGGACGATCAAG

Downstream 100 bases:

>100_bases
ATCTCAAGCAGGGGGCGGTTCCACCCGGGCAGGCTCGATCCCGGGACGCGGCTTCGGGGCGGCGCTATACTGCCCGAACA
ACTTCTGCAGGCGCTCCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MHYRLYLSGIALLWAGMNALPANAQGVLPAGGPLGLRQALSQAELRNPQLVVAQRNLGIGLAGITAAGAAPNPQLTVYWG
FGTVYTEDGSPQTVGLSQKLETAGKRPARLALADAQYRLALLQYNATRFEIRSQVRKAYAQFAAAQAGGRALEVQERLAQ
RLLEVARKRSAAGESPKTDALQTQLEVNRLKTQQTEALGRVEQAQIALSGLLGRDPEETLDIDDLGLFELSLEKTALVPL
PGAPVPLVATFLERAYRARLDLQAAEQQREVARRQLALARAQRVPDVNVATGYLFTTRTNSDPQAQGVYVGVGIDLPVFY
NNQGEVKLAELAGEQSSLQIDALKLQIAVEVRTAYRALLNARESLRRHRNQLLPAAQDVVQLTQLSYELGKRDLGEVVLA
QQAAQAVLESYLEAVVAYQGAWADLEKAVGEPLDV

Sequences:

>Translated_435_residues
MHYRLYLSGIALLWAGMNALPANAQGVLPAGGPLGLRQALSQAELRNPQLVVAQRNLGIGLAGITAAGAAPNPQLTVYWG
FGTVYTEDGSPQTVGLSQKLETAGKRPARLALADAQYRLALLQYNATRFEIRSQVRKAYAQFAAAQAGGRALEVQERLAQ
RLLEVARKRSAAGESPKTDALQTQLEVNRLKTQQTEALGRVEQAQIALSGLLGRDPEETLDIDDLGLFELSLEKTALVPL
PGAPVPLVATFLERAYRARLDLQAAEQQREVARRQLALARAQRVPDVNVATGYLFTTRTNSDPQAQGVYVGVGIDLPVFY
NNQGEVKLAELAGEQSSLQIDALKLQIAVEVRTAYRALLNARESLRRHRNQLLPAAQDVVQLTQLSYELGKRDLGEVVLA
QQAAQAVLESYLEAVVAYQGAWADLEKAVGEPLDV
>Mature_435_residues
MHYRLYLSGIALLWAGMNALPANAQGVLPAGGPLGLRQALSQAELRNPQLVVAQRNLGIGLAGITAAGAAPNPQLTVYWG
FGTVYTEDGSPQTVGLSQKLETAGKRPARLALADAQYRLALLQYNATRFEIRSQVRKAYAQFAAAQAGGRALEVQERLAQ
RLLEVARKRSAAGESPKTDALQTQLEVNRLKTQQTEALGRVEQAQIALSGLLGRDPEETLDIDDLGLFELSLEKTALVPL
PGAPVPLVATFLERAYRARLDLQAAEQQREVARRQLALARAQRVPDVNVATGYLFTTRTNSDPQAQGVYVGVGIDLPVFY
NNQGEVKLAELAGEQSSLQIDALKLQIAVEVRTAYRALLNARESLRRHRNQLLPAAQDVVQLTQLSYELGKRDLGEVVLA
QQAAQAVLESYLEAVVAYQGAWADLEKAVGEPLDV

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47182; Mature: 47182

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRLYLSGIALLWAGMNALPANAQGVLPAGGPLGLRQALSQAELRNPQLVVAQRNLGIG
CEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEE
LAGITAAGAAPNPQLTVYWGFGTVYTEDGSPQTVGLSQKLETAGKRPARLALADAQYRLA
EECCEECCCCCCCCEEEEEECCEEEECCCCCCEECHHHHHHHCCCCCCEEEEECCHHEEE
LLQYNATRFEIRSQVRKAYAQFAAAQAGGRALEVQERLAQRLLEVARKRSAAGESPKTDA
EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LQTQLEVNRLKTQQTEALGRVEQAQIALSGLLGRDPEETLDIDDLGLFELSLEKTALVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCEEEEEC
PGAPVPLVATFLERAYRARLDLQAAEQQREVARRQLALARAQRVPDVNVATGYLFTTRTN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCC
SDPQAQGVYVGVGIDLPVFYNNQGEVKLAELAGEQSSLQIDALKLQIAVEVRTAYRALLN
CCCCCCEEEEEECEEEEEEECCCCCEEEHHHCCCCCCEEEEEEEEEEEEHHHHHHHHHHH
ARESLRRHRNQLLPAAQDVVQLTQLSYELGKRDLGEVVLAQQAAQAVLESYLEAVVAYQG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AWADLEKAVGEPLDV
CHHHHHHHCCCCCCC
>Mature Secondary Structure
MHYRLYLSGIALLWAGMNALPANAQGVLPAGGPLGLRQALSQAELRNPQLVVAQRNLGIG
CEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEE
LAGITAAGAAPNPQLTVYWGFGTVYTEDGSPQTVGLSQKLETAGKRPARLALADAQYRLA
EECCEECCCCCCCCEEEEEECCEEEECCCCCCEECHHHHHHHCCCCCCEEEEECCHHEEE
LLQYNATRFEIRSQVRKAYAQFAAAQAGGRALEVQERLAQRLLEVARKRSAAGESPKTDA
EEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LQTQLEVNRLKTQQTEALGRVEQAQIALSGLLGRDPEETLDIDDLGLFELSLEKTALVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCEEEEEC
PGAPVPLVATFLERAYRARLDLQAAEQQREVARRQLALARAQRVPDVNVATGYLFTTRTN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCC
SDPQAQGVYVGVGIDLPVFYNNQGEVKLAELAGEQSSLQIDALKLQIAVEVRTAYRALLN
CCCCCCEEEEEECEEEEEEECCCCCEEEHHHCCCCCCEEEEEEEEEEEEHHHHHHHHHHH
ARESLRRHRNQLLPAAQDVVQLTQLSYELGKRDLGEVVLAQQAAQAVLESYLEAVVAYQG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AWADLEKAVGEPLDV
CHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]