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The map label for this gene is btuR [H]

Identifier: 37523080

GI number: 37523080

Start: 3715718

End: 3716260

Strand: Reverse

Name: btuR [H]

Synonym: gll3511

Alternate gene names: 37523080

Gene position: 3716260-3715718 (Counterclockwise)

Preceding gene: 37523084

Following gene: 37523079

Centisome position: 79.76

GC content: 61.88

Gene sequence:

>543_bases
ATGGTAGCGCAAGTGGATGCATCGAACCCCACCTCCAAGGCCGTCGCTCCGTCGCTGGCTCTGCAGGGCACTCTCCAGAT
CGTCACCGGTCCCGACCGGGCCTTCAACGCCGGGGTGATCGCCCACGCGCTGCGGGCCGCAGGCCAGGGCGTGCCGGTAC
TTGTGGTGCAATTTCTCAAAGGCGGCATCGGTCAAGGTCCGGACAACCCGATGTATCTGTGCCAGGGTCTGCGCTGGGTG
CGCTGCAACCTGCAGCGCTGCCTGGACACGCCGCACCTGGAAATCGAAGAACAAAAAGCGATGTACGAACTGTGGAAGTA
CACCCGCCGGGCGGTCCACAGCGGTCGGTTCGGTCTGGTGGTGCTCGACGAATTGAGCCTGGCGATCCAATTTGGTTTGA
TTGCTGAGACAGAAGTGATCGAACTATTGGAGCAGCGGCCTTCGTATATGGACGTCATCCTGACCGGCCCCGAGATGCCC
ATCGCCCTGAGCGCCATGGCCGATCAGGTGACCGAACTGCGCAAAAGCGCCATCCAGCCCTAA

Upstream 100 bases:

>100_bases
ATCCGGCTTCGAAGGCGCCGGCTCGGTGCGGACGGCTTGACTACCTACCGCATCTAGTGTTTTATAGCCACAGAACACCA
CACAGATGGAGTCCGCTCGA

Downstream 100 bases:

>100_bases
GATCGCAGCAGGACTTGCGGGGGGCGGATGCTCAACAGTGACAGCTGGATCAAACAACGCGCCGCCGAGGGCATGATCGC
CCCGTTCGAGGCCGAATTGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MVAQVDASNPTSKAVAPSLALQGTLQIVTGPDRAFNAGVIAHALRAAGQGVPVLVVQFLKGGIGQGPDNPMYLCQGLRWV
RCNLQRCLDTPHLEIEEQKAMYELWKYTRRAVHSGRFGLVVLDELSLAIQFGLIAETEVIELLEQRPSYMDVILTGPEMP
IALSAMADQVTELRKSAIQP

Sequences:

>Translated_180_residues
MVAQVDASNPTSKAVAPSLALQGTLQIVTGPDRAFNAGVIAHALRAAGQGVPVLVVQFLKGGIGQGPDNPMYLCQGLRWV
RCNLQRCLDTPHLEIEEQKAMYELWKYTRRAVHSGRFGLVVLDELSLAIQFGLIAETEVIELLEQRPSYMDVILTGPEMP
IALSAMADQVTELRKSAIQP
>Mature_180_residues
MVAQVDASNPTSKAVAPSLALQGTLQIVTGPDRAFNAGVIAHALRAAGQGVPVLVVQFLKGGIGQGPDNPMYLCQGLRWV
RCNLQRCLDTPHLEIEEQKAMYELWKYTRRAVHSGRFGLVVLDELSLAIQFGLIAETEVIELLEQRPSYMDVILTGPEMP
IALSAMADQVTELRKSAIQP

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=168, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19621; Mature: 19621

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQVDASNPTSKAVAPSLALQGTLQIVTGPDRAFNAGVIAHALRAAGQGVPVLVVQFLK
CCEECCCCCCCCHHHCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGIGQGPDNPMYLCQGLRWVRCNLQRCLDTPHLEIEEQKAMYELWKYTRRAVHSGRFGLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VLDELSLAIQFGLIAETEVIELLEQRPSYMDVILTGPEMPIALSAMADQVTELRKSAIQP
EHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAQVDASNPTSKAVAPSLALQGTLQIVTGPDRAFNAGVIAHALRAAGQGVPVLVVQFLK
CCEECCCCCCCCHHHCCHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGIGQGPDNPMYLCQGLRWVRCNLQRCLDTPHLEIEEQKAMYELWKYTRRAVHSGRFGLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VLDELSLAIQFGLIAETEVIELLEQRPSYMDVILTGPEMPIALSAMADQVTELRKSAIQP
EHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]