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The map label for this gene is bioD

Identifier: 37523078

GI number: 37523078

Start: 3714390

End: 3715079

Strand: Reverse

Name: bioD

Synonym: gvip476

Alternate gene names: 37523078

Gene position: 3715079-3714390 (Counterclockwise)

Preceding gene: 37523079

Following gene: 37523076

Centisome position: 79.74

GC content: 67.1

Gene sequence:

>690_bases
ATGGCGGGCGTACTGGTAAGCGGCACCGACACCGGGGCCGGCAAGACGATCTTATGCGCGGCCCTCGCTGCCTGGTGGCT
CGCCCATCGCCGCACGCCGGCAGCCATCCTCAAGCCCGTCCAGTGCGGCCCGGGGGATCGCGAGTACTACCGCACGGTCT
TCGGCGACGCGCTTTCGGTGCTCAATCCGCTGTATTTCGAAGCCCCCCTCGCCCCGCCCCTGGCGGCGGCCCGCGAAGGG
CAGACAGTCGATATCGGTCTGCTTTGGAAAAGTTACTGCGAGGCGGCGGCCGGCCACGCCCTGGTCCTAGTCGAAGGGGT
GGGCGGTCTCGGTTGCCCGCTCGGTTGGGATTACACCGTGGCGGATCTGGCGCGCGACTGGCGCCTGCCGGTGCTGCTGG
TGGCTCCTCTGCGGCTCGGAGTGGTCGGTCAACTGGTGGCCCACACGGGTTTTGCCCGTGCTCAGAATCTGGATCTGAGC
GCGTTGGTCCTATCGGAGATCGAACCGGTGAGCGCAGAGCAGCGCGCCCAGTGGGCGGATGTACAACTTATCGAGAACCT
CTGCCACCTGCCGGTGCTGGGGGTGCTTTCCCACCTGGAAGCTGCTACCGACCGCGCAGCACTCGCAGCCGCGGGGAGCG
GATTGTGGCTGGAGGCGGCTGGGACATTGTTCACAGCAGAGCGCGGATAA

Upstream 100 bases:

>100_bases
TTACCACCGACCAGGTGCCCGAGGTGACCTACGCGACGCGCAAGGACGGCCCCGGCAAGTACCAATCGCAGGAACAGCGC
ATCGTGCTGCCGCGGGTCTG

Downstream 100 bases:

>100_bases
ATTCGTCGTCGCGGAAGCGCCCGCTCCCCCGGCCGCGGGCGGAGCGCAGGTCGCCCTGGCGGACCACCACCAGATCGAGG
GACGGGATGACGTAGAGCCG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAGVLVSGTDTGAGKTILCAALAAWWLAHRRTPAAILKPVQCGPGDREYYRTVFGDALSVLNPLYFEAPLAPPLAAAREG
QTVDIGLLWKSYCEAAAGHALVLVEGVGGLGCPLGWDYTVADLARDWRLPVLLVAPLRLGVVGQLVAHTGFARAQNLDLS
ALVLSEIEPVSAEQRAQWADVQLIENLCHLPVLGVLSHLEAATDRAALAAAGSGLWLEAAGTLFTAERG

Sequences:

>Translated_229_residues
MAGVLVSGTDTGAGKTILCAALAAWWLAHRRTPAAILKPVQCGPGDREYYRTVFGDALSVLNPLYFEAPLAPPLAAAREG
QTVDIGLLWKSYCEAAAGHALVLVEGVGGLGCPLGWDYTVADLARDWRLPVLLVAPLRLGVVGQLVAHTGFARAQNLDLS
ALVLSEIEPVSAEQRAQWADVQLIENLCHLPVLGVLSHLEAATDRAALAAAGSGLWLEAAGTLFTAERG
>Mature_228_residues
AGVLVSGTDTGAGKTILCAALAAWWLAHRRTPAAILKPVQCGPGDREYYRTVFGDALSVLNPLYFEAPLAPPLAAAREGQ
TVDIGLLWKSYCEAAAGHALVLVEGVGGLGCPLGWDYTVADLARDWRLPVLLVAPLRLGVVGQLVAHTGFARAQNLDLSA
LVLSEIEPVSAEQRAQWADVQLIENLCHLPVLGVLSHLEAATDRAALAAAGSGLWLEAAGTLFTAERG

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family

Homologues:

Organism=Escherichia coli, GI1786995, Length=217, Percent_Identity=29.4930875576037, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOD_GLOVI (Q7NFL5)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926455.1
- ProteinModelPortal:   Q7NFL5
- GeneID:   2601913
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3509
- HOGENOM:   HBG650065
- OMA:   ALAAYWQ
- ProtClustDB:   PRK00090
- BioCyc:   GVIO251221:GLL3509-MONOMER
- BRENDA:   6.3.3.3
- HAMAP:   MF_00336
- InterPro:   IPR004472
- PIRSF:   PIRSF006755
- TIGRFAMs:   TIGR00347

Pfam domain/function: NA

EC number: =6.3.3.3

Molecular weight: Translated: 24051; Mature: 23920

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVLVSGTDTGAGKTILCAALAAWWLAHRRTPAAILKPVQCGPGDREYYRTVFGDALSV
CCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
LNPLYFEAPLAPPLAAAREGQTVDIGLLWKSYCEAAAGHALVLVEGVGGLGCPLGWDYTV
HCHHHHCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHH
ADLARDWRLPVLLVAPLRLGVVGQLVAHTGFARAQNLDLSALVLSEIEPVSAEQRAQWAD
HHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
VQLIENLCHLPVLGVLSHLEAATDRAALAAAGSGLWLEAAGTLFTAERG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCC
>Mature Secondary Structure 
AGVLVSGTDTGAGKTILCAALAAWWLAHRRTPAAILKPVQCGPGDREYYRTVFGDALSV
CCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHH
LNPLYFEAPLAPPLAAAREGQTVDIGLLWKSYCEAAAGHALVLVEGVGGLGCPLGWDYTV
HCHHHHCCCCCCCHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHH
ADLARDWRLPVLLVAPLRLGVVGQLVAHTGFARAQNLDLSALVLSEIEPVSAEQRAQWAD
HHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCCHHHHHHHHH
VQLIENLCHLPVLGVLSHLEAATDRAALAAAGSGLWLEAAGTLFTAERG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292