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The map label for this gene is tkt [H]

Identifier: 37523033

GI number: 37523033

Start: 3672527

End: 3674449

Strand: Reverse

Name: tkt [H]

Synonym: gll3464

Alternate gene names: 37523033

Gene position: 3674449-3672527 (Counterclockwise)

Preceding gene: 37523034

Following gene: 37523031

Centisome position: 78.87

GC content: 62.92

Gene sequence:

>1923_bases
ATGTGGATCATGACAACAACCACCGTTCGCTTTCCGATCGATATCAGTGCCTACAAGCCGCTGGCGCTGGATTTTGCCAA
TCCGGTGCTGAGCGCCGAACAGCGCGAGACGCTCAGAGCGAATATCCAGTTTTGTCGCGATGCGATTGTGTTCTTCACCG
CCACCGGGGCGGCCCGGGGAGTGGGCGGCCACACCGGCGGACCCTACGACACGGTGCCCGAGGTGATGATCCTCGAAGCG
CTCTTCCGGGGCAATCCCGACAAGTTTGTGCCCATCTTTTTTGACGAAGCCGGTCACCGGGTGGCCACCCAGTACCTGAT
GGCGGCCCTGCACGGCGAATTGCCCTTCGAGCAACTGCTGCAGTACCGCGCCGCCGATTCGCACCTGCCCGGTCACCCCG
AACTGGGGCTCACCCCCGGCGTCAAATTCAGCTCCGGACGGCTCGGGCACATGTGGCCCTACGTCAACGGCGTGGCGATG
GCCAATCCCGATAAGGTCGTCTTCTGCCTGGGTTCGGACGGTTCGCAGCAGGAGGGCAACGACGCGGAAGCCGCCCGCCT
TGCTGTCGCCCAAGGGCTCAACGTCAAGCTCATCGTCGACGACAACGACGTGACAATCGCCGGACACCCGTCGAAGTACC
TGCCGGGCTTCAGCGTCGCCAAGACCCTGGCGGGCCACGGACTCGCCATCGATGAAGGGGACGGCGAAGATCTCGACGGG
TTGTACGCCCGCATTTGTACGGCGATCACCGCCGCCGGCCCGGTCGCCGTCGTCAACAAGCGCCCCATGTGCGTGGGCAT
CGACGGCCTCGAGGGTTCGACCCACGGCCACGACGTCATTTCGGTGGATCTGGCGGTTGCTTATCTTGAAAAGCGCGGCC
AGAGCGAGGCGGTGAAGTTCCTCAAAAACGTCGCCAAACCCAAGCAGAGCTACACTTTCCTGGGCTCAGGCACCCAGATG
GGTTCCAACCGCAACGTCTTCGGCGAGGCGGTGGTGGCGGTGCTGGGCCGCATGGACGCGGCGGAGCGCAAGGCGCGGGT
CATGTGCATCGACAGCGACCTCGAAGGCTCCTGCGGTCTGAAGAAGATCCACGACACTTTCCCGGAAATTTTCGTCGCCT
CTGGGATCATGGAGCGGGGCAATCTTTCCGCCGCCGCCGGTTTCGGCATGGAGAAGGGCAAGCAGGGCATCTTCGGGACC
TTCAGCGCCTTTTTGGAGATGTGCATTTCAGAGATCACCATGGCGCGGCTCAACTACTCGAACGTGCTGTGCCACTTCTC
CCACTCCGGCATCGACGACATGGCCGACAACACCTGCCACTTCGGCCTCAACAACTTCTTTGCCGACAACGGCCTGGATG
ACGGCTACGAAACCCGGCTCTACTTCCCGGCGGACGCGGCCCAGATGAAAGCCTGCGTGGAGGCGGTCTTCCACCAGCCG
GGTTTGCGCTTTATCTTCTCGACGCGCTCCAAGACCCCCAACATCCTGGATGCCGACGGCAAGGACCTGCACGGCGAAGG
CTACACTTTTACTCCGGGTGCCGACGAGGTGGTGCGCGAGGGCACGGCGGGCTACATCGTGAGCTTCGGCGAATCGCTTT
ACCGGGCGCTCGATGCGGTCGAACGCCTCAAGGAGGAGGGCATCGACGTGGGTCTCATCAACAAGCCGACCCTCAACGTC
ATCGACGAAAAGATGCTCGCCAAAGTCGGCAGTTCCCCGATGGTGCTGGTGGTTGAATCGTTCAACCGCCGCACGGGCCT
CGGTAGCCGCTTCGGCTCCTGGCTGTTGGAGCGCGGTTACGCCCCCAAATTCGCCCACCTGGGCACCCACAAAGAAGGCT
GCGGCGGCCTGTGGGAGCAGTTCCCGCACCAGGGTATCGACCCGGTGGGGATCATAGCCAAGGTGAAGGAACTGGTGGGC
TAG

Upstream 100 bases:

>100_bases
CGAGGTTTTCCTGGAAACCGATGCTTGATACGCGGGCGCAAATCCGCTCAGCGAGAGCATCGCAATCGTCACATCCCCGA
CTGACGGCACCTTAAATAGG

Downstream 100 bases:

>100_bases
GGGACTTTTGCGAACCGATTTACTCGTGTCGCGCAAATCGGTTCGCGAATTACTCATCTCATCCAGATAGAAGGCCGACG
GTAACTCAAAGGTTGTCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MWIMTTTTVRFPIDISAYKPLALDFANPVLSAEQRETLRANIQFCRDAIVFFTATGAARGVGGHTGGPYDTVPEVMILEA
LFRGNPDKFVPIFFDEAGHRVATQYLMAALHGELPFEQLLQYRAADSHLPGHPELGLTPGVKFSSGRLGHMWPYVNGVAM
ANPDKVVFCLGSDGSQQEGNDAEAARLAVAQGLNVKLIVDDNDVTIAGHPSKYLPGFSVAKTLAGHGLAIDEGDGEDLDG
LYARICTAITAAGPVAVVNKRPMCVGIDGLEGSTHGHDVISVDLAVAYLEKRGQSEAVKFLKNVAKPKQSYTFLGSGTQM
GSNRNVFGEAVVAVLGRMDAAERKARVMCIDSDLEGSCGLKKIHDTFPEIFVASGIMERGNLSAAAGFGMEKGKQGIFGT
FSAFLEMCISEITMARLNYSNVLCHFSHSGIDDMADNTCHFGLNNFFADNGLDDGYETRLYFPADAAQMKACVEAVFHQP
GLRFIFSTRSKTPNILDADGKDLHGEGYTFTPGADEVVREGTAGYIVSFGESLYRALDAVERLKEEGIDVGLINKPTLNV
IDEKMLAKVGSSPMVLVVESFNRRTGLGSRFGSWLLERGYAPKFAHLGTHKEGCGGLWEQFPHQGIDPVGIIAKVKELVG

Sequences:

>Translated_640_residues
MWIMTTTTVRFPIDISAYKPLALDFANPVLSAEQRETLRANIQFCRDAIVFFTATGAARGVGGHTGGPYDTVPEVMILEA
LFRGNPDKFVPIFFDEAGHRVATQYLMAALHGELPFEQLLQYRAADSHLPGHPELGLTPGVKFSSGRLGHMWPYVNGVAM
ANPDKVVFCLGSDGSQQEGNDAEAARLAVAQGLNVKLIVDDNDVTIAGHPSKYLPGFSVAKTLAGHGLAIDEGDGEDLDG
LYARICTAITAAGPVAVVNKRPMCVGIDGLEGSTHGHDVISVDLAVAYLEKRGQSEAVKFLKNVAKPKQSYTFLGSGTQM
GSNRNVFGEAVVAVLGRMDAAERKARVMCIDSDLEGSCGLKKIHDTFPEIFVASGIMERGNLSAAAGFGMEKGKQGIFGT
FSAFLEMCISEITMARLNYSNVLCHFSHSGIDDMADNTCHFGLNNFFADNGLDDGYETRLYFPADAAQMKACVEAVFHQP
GLRFIFSTRSKTPNILDADGKDLHGEGYTFTPGADEVVREGTAGYIVSFGESLYRALDAVERLKEEGIDVGLINKPTLNV
IDEKMLAKVGSSPMVLVVESFNRRTGLGSRFGSWLLERGYAPKFAHLGTHKEGCGGLWEQFPHQGIDPVGIIAKVKELVG
>Mature_640_residues
MWIMTTTTVRFPIDISAYKPLALDFANPVLSAEQRETLRANIQFCRDAIVFFTATGAARGVGGHTGGPYDTVPEVMILEA
LFRGNPDKFVPIFFDEAGHRVATQYLMAALHGELPFEQLLQYRAADSHLPGHPELGLTPGVKFSSGRLGHMWPYVNGVAM
ANPDKVVFCLGSDGSQQEGNDAEAARLAVAQGLNVKLIVDDNDVTIAGHPSKYLPGFSVAKTLAGHGLAIDEGDGEDLDG
LYARICTAITAAGPVAVVNKRPMCVGIDGLEGSTHGHDVISVDLAVAYLEKRGQSEAVKFLKNVAKPKQSYTFLGSGTQM
GSNRNVFGEAVVAVLGRMDAAERKARVMCIDSDLEGSCGLKKIHDTFPEIFVASGIMERGNLSAAAGFGMEKGKQGIFGT
FSAFLEMCISEITMARLNYSNVLCHFSHSGIDDMADNTCHFGLNNFFADNGLDDGYETRLYFPADAAQMKACVEAVFHQP
GLRFIFSTRSKTPNILDADGKDLHGEGYTFTPGADEVVREGTAGYIVSFGESLYRALDAVERLKEEGIDVGLINKPTLNV
IDEKMLAKVGSSPMVLVVESFNRRTGLGSRFGSWLLERGYAPKFAHLGTHKEGCGGLWEQFPHQGIDPVGIIAKVKELVG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=537, Percent_Identity=23.8361266294227, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4507521, Length=537, Percent_Identity=23.8361266294227, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI133778974, Length=526, Percent_Identity=24.5247148288973, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788808, Length=226, Percent_Identity=29.2035398230088, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17539652, Length=506, Percent_Identity=26.2845849802372, Blast_Score=107, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325331, Length=245, Percent_Identity=31.8367346938775, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319593, Length=256, Percent_Identity=28.515625, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24666278, Length=537, Percent_Identity=24.5810055865922, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24645119, Length=550, Percent_Identity=24.7272727272727, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551847, Length=550, Percent_Identity=24.7272727272727, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550715, Length=550, Percent_Identity=24.7272727272727, Blast_Score=94, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 68992; Mature: 68992

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIMTTTTVRFPIDISAYKPLALDFANPVLSAEQRETLRANIQFCRDAIVFFTATGAARG
CEEEEEEEEEEEEEECCCCCEEHHHCCHHHCHHHHHHHHHHHHHHHHEEEEEEECCCCCC
VGGHTGGPYDTVPEVMILEALFRGNPDKFVPIFFDEAGHRVATQYLMAALHGELPFEQLL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
QYRAADSHLPGHPELGLTPGVKFSSGRLGHMWPYVNGVAMANPDKVVFCLGSDGSQQEGN
HHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCC
DAEAARLAVAQGLNVKLIVDDNDVTIAGHPSKYLPGFSVAKTLAGHGLAIDEGDGEDLDG
CHHHHHHHHHCCCEEEEEEECCCEEEECCCHHHCCCHHHHHHHCCCCEEEECCCCCCHHH
LYARICTAITAAGPVAVVNKRPMCVGIDGLEGSTHGHDVISVDLAVAYLEKRGQSEAVKF
HHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHH
LKNVAKPKQSYTFLGSGTQMGSNRNVFGEAVVAVLGRMDAAERKARVMCIDSDLEGSCGL
HHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCH
KKIHDTFPEIFVASGIMERGNLSAAAGFGMEKGKQGIFGTFSAFLEMCISEITMARLNYS
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NVLCHFSHSGIDDMADNTCHFGLNNFFADNGLDDGYETRLYFPADAAQMKACVEAVFHQP
CEEEEECCCCCCHHCCCCEECCCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCC
GLRFIFSTRSKTPNILDADGKDLHGEGYTFTPGADEVVREGTAGYIVSFGESLYRALDAV
CCEEEEECCCCCCCEECCCCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
ERLKEEGIDVGLINKPTLNVIDEKMLAKVGSSPMVLVVESFNRRTGLGSRFGSWLLERGY
HHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
APKFAHLGTHKEGCGGLWEQFPHQGIDPVGIIAKVKELVG
CCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MWIMTTTTVRFPIDISAYKPLALDFANPVLSAEQRETLRANIQFCRDAIVFFTATGAARG
CEEEEEEEEEEEEEECCCCCEEHHHCCHHHCHHHHHHHHHHHHHHHHEEEEEEECCCCCC
VGGHTGGPYDTVPEVMILEALFRGNPDKFVPIFFDEAGHRVATQYLMAALHGELPFEQLL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
QYRAADSHLPGHPELGLTPGVKFSSGRLGHMWPYVNGVAMANPDKVVFCLGSDGSQQEGN
HHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCC
DAEAARLAVAQGLNVKLIVDDNDVTIAGHPSKYLPGFSVAKTLAGHGLAIDEGDGEDLDG
CHHHHHHHHHCCCEEEEEEECCCEEEECCCHHHCCCHHHHHHHCCCCEEEECCCCCCHHH
LYARICTAITAAGPVAVVNKRPMCVGIDGLEGSTHGHDVISVDLAVAYLEKRGQSEAVKF
HHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHH
LKNVAKPKQSYTFLGSGTQMGSNRNVFGEAVVAVLGRMDAAERKARVMCIDSDLEGSCGL
HHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCH
KKIHDTFPEIFVASGIMERGNLSAAAGFGMEKGKQGIFGTFSAFLEMCISEITMARLNYS
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NVLCHFSHSGIDDMADNTCHFGLNNFFADNGLDDGYETRLYFPADAAQMKACVEAVFHQP
CEEEEECCCCCCHHCCCCEECCCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCC
GLRFIFSTRSKTPNILDADGKDLHGEGYTFTPGADEVVREGTAGYIVSFGESLYRALDAV
CCEEEEECCCCCCCEECCCCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
ERLKEEGIDVGLINKPTLNVIDEKMLAKVGSSPMVLVVESFNRRTGLGSRFGSWLLERGY
HHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
APKFAHLGTHKEGCGGLWEQFPHQGIDPVGIIAKVKELVG
CCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]