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The map label for this gene is etfA [H]

Identifier: 37522932

GI number: 37522932

Start: 3572081

End: 3573166

Strand: Reverse

Name: etfA [H]

Synonym: gll3363

Alternate gene names: 37522932

Gene position: 3573166-3572081 (Counterclockwise)

Preceding gene: 37522933

Following gene: 37522931

Centisome position: 76.69

GC content: 64.0

Gene sequence:

>1086_bases
ATGAGCACCAAACAAGTCCTCATCTTTGTCGAACAGGAGGACGGCTGCGCCCGGCCGGTCGCCTTTGAACTGTTGGGAGC
GGGCCGGATGCTGGCCAATAAACTCGGGGCGGAACTGGCGGCATTCGTAGCCTGCGATTCGGTGGGAGAACTGCCCGAGA
CGCTCGTCGCCCACGGGGCCGACCGGGTCTACGTGGCGGAGCATCCGGAACTGGCCACCTACCGCACCCTGCCCTACCGG
CGGGTGCTCATCGATCTCATCGCGGCGATGGACACCCCTCCGCACATCGTGCTGTTCGGTTCCACCACCACCGGCCGGGA
TTTGGCCCCGCGCATCGCCGCCTACTTCGAGACGGGGCTGACTGCCGATTGCACAGAACTCGACATCGGTCCCTACGAGC
ACACCAACGCCCAAGATCCGAGCAAGGTGGGTCTCTACCCCGACTGTCTCTACGCCATTCGTCCCAGCTTCGGCGAATCG
CTCAAAGCCCGCATCCTCGGTCCCTGGAAAAATCCCCAGATGGCCACGGTGCGCTCCGGGGTGATGGTGCCGCTCGCTCC
CGACGCCACCCGCACGGGCGTGGTCCAGTCGGTCCCGGTGCACCTCGAAAGCGCGGATCTGCAATTGGTGGTCGCCGAGA
CCTTGCGTTCGCTGGGCGAGCAGGTCGAACTGCAGGGCGCCGAGGTGATCGTCTCGGGGGGCTACGGTCTGGGCAATCCC
GAGGGTTTTGCCCTGATGTACCAGCTCGCCGCTTGCTTCGAAAACAGTGCCGTGGGTTCCTCGCGCAAGGCGGTGGACGC
CGGTTGGATCGCCCACGCCCACCAGGTGGGCCAGACGGGCAAGACCGTGCGCCCGAAGCTCTATATCGCCTGCGGCATCT
CGGGGGCCATCCAGCACCGGGTCGGCATGGACAAATCGGCCACAATTGTGGCCATCAACAAAGACTCCAACGCCCCAATC
TTTAAATTTGCCCACCACGGCATCGTGGGCGATCTCCACCAGGTCATCCCGGAACTCATCCGCCAACTCAAACTCCAGAA
GACCTCTACCCCGGACACGAGCCATGTCGCCACCCATTCGCTATGA

Upstream 100 bases:

>100_bases
AAATTGGCGGCAACTGTACCCTCTACCAGGGCAAGCCTCTCCAGCAACTGGTAGACGATTTGCTTGCCGCCCAGGTGATT
GCACCGGAGCTTGTGAAGCA

Downstream 100 bases:

>100_bases
TTTGCTGCTGGTCGGGGGCAGCGCTTCGAATCTGATCCTTGCCCACCGCCTGTTGGATCTGGCCGGCAAAAGCGGCCTGC
CCCTCACCATCGCCCTGGTC

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSTKQVLIFVEQEDGCARPVAFELLGAGRMLANKLGAELAAFVACDSVGELPETLVAHGADRVYVAEHPELATYRTLPYR
RVLIDLIAAMDTPPHIVLFGSTTTGRDLAPRIAAYFETGLTADCTELDIGPYEHTNAQDPSKVGLYPDCLYAIRPSFGES
LKARILGPWKNPQMATVRSGVMVPLAPDATRTGVVQSVPVHLESADLQLVVAETLRSLGEQVELQGAEVIVSGGYGLGNP
EGFALMYQLAACFENSAVGSSRKAVDAGWIAHAHQVGQTGKTVRPKLYIACGISGAIQHRVGMDKSATIVAINKDSNAPI
FKFAHHGIVGDLHQVIPELIRQLKLQKTSTPDTSHVATHSL

Sequences:

>Translated_361_residues
MSTKQVLIFVEQEDGCARPVAFELLGAGRMLANKLGAELAAFVACDSVGELPETLVAHGADRVYVAEHPELATYRTLPYR
RVLIDLIAAMDTPPHIVLFGSTTTGRDLAPRIAAYFETGLTADCTELDIGPYEHTNAQDPSKVGLYPDCLYAIRPSFGES
LKARILGPWKNPQMATVRSGVMVPLAPDATRTGVVQSVPVHLESADLQLVVAETLRSLGEQVELQGAEVIVSGGYGLGNP
EGFALMYQLAACFENSAVGSSRKAVDAGWIAHAHQVGQTGKTVRPKLYIACGISGAIQHRVGMDKSATIVAINKDSNAPI
FKFAHHGIVGDLHQVIPELIRQLKLQKTSTPDTSHVATHSL
>Mature_360_residues
STKQVLIFVEQEDGCARPVAFELLGAGRMLANKLGAELAAFVACDSVGELPETLVAHGADRVYVAEHPELATYRTLPYRR
VLIDLIAAMDTPPHIVLFGSTTTGRDLAPRIAAYFETGLTADCTELDIGPYEHTNAQDPSKVGLYPDCLYAIRPSFGESL
KARILGPWKNPQMATVRSGVMVPLAPDATRTGVVQSVPVHLESADLQLVVAETLRSLGEQVELQGAEVIVSGGYGLGNPE
GFALMYQLAACFENSAVGSSRKAVDAGWIAHAHQVGQTGKTVRPKLYIACGISGAIQHRVGMDKSATIVAINKDSNAPIF
KFAHHGIVGDLHQVIPELIRQLKLQKTSTPDTSHVATHSL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=353, Percent_Identity=33.7110481586402, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI189181759, Length=122, Percent_Identity=60.655737704918, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1786226, Length=327, Percent_Identity=29.9694189602446, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1787990, Length=292, Percent_Identity=30.1369863013699, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506929, Length=342, Percent_Identity=34.7953216374269, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6325261, Length=339, Percent_Identity=29.2035398230088, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17136898, Length=343, Percent_Identity=35.2769679300292, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24652801, Length=343, Percent_Identity=35.2769679300292, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 38652; Mature: 38521

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKQVLIFVEQEDGCARPVAFELLGAGRMLANKLGAELAAFVACDSVGELPETLVAHGA
CCCCEEEEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
DRVYVAEHPELATYRTLPYRRVLIDLIAAMDTPPHIVLFGSTTTGRDLAPRIAAYFETGL
CEEEEECCCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
TADCTELDIGPYEHTNAQDPSKVGLYPDCLYAIRPSFGESLKARILGPWKNPQMATVRSG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHCC
VMVPLAPDATRTGVVQSVPVHLESADLQLVVAETLRSLGEQVELQGAEVIVSGGYGLGNP
EEEEECCCCCCCCCEEECCEEEECCCEEEEHHHHHHHHHHHEEECCCEEEEECCCCCCCC
EGFALMYQLAACFENSAVGSSRKAVDAGWIAHAHQVGQTGKTVRPKLYIACGISGAIQHR
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHH
VGMDKSATIVAINKDSNAPIFKFAHHGIVGDLHQVIPELIRQLKLQKTSTPDTSHVATHS
CCCCCCEEEEEEECCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
L
C
>Mature Secondary Structure 
STKQVLIFVEQEDGCARPVAFELLGAGRMLANKLGAELAAFVACDSVGELPETLVAHGA
CCCEEEEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
DRVYVAEHPELATYRTLPYRRVLIDLIAAMDTPPHIVLFGSTTTGRDLAPRIAAYFETGL
CEEEEECCCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
TADCTELDIGPYEHTNAQDPSKVGLYPDCLYAIRPSFGESLKARILGPWKNPQMATVRSG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHCC
VMVPLAPDATRTGVVQSVPVHLESADLQLVVAETLRSLGEQVELQGAEVIVSGGYGLGNP
EEEEECCCCCCCCCEEECCEEEECCCEEEEHHHHHHHHHHHEEECCCEEEEECCCCCCCC
EGFALMYQLAACFENSAVGSSRKAVDAGWIAHAHQVGQTGKTVRPKLYIACGISGAIQHR
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHH
VGMDKSATIVAINKDSNAPIFKFAHHGIVGDLHQVIPELIRQLKLQKTSTPDTSHVATHS
CCCCCCEEEEEEECCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA