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The map label for this gene is etfD [H]

Identifier: 37522931

GI number: 37522931

Start: 3570385

End: 3572103

Strand: Reverse

Name: etfD [H]

Synonym: gll3362

Alternate gene names: 37522931

Gene position: 3572103-3570385 (Counterclockwise)

Preceding gene: 37522932

Following gene: 37522928

Centisome position: 76.67

GC content: 62.07

Gene sequence:

>1719_bases
ATGTCGCCACCCATTCGCTATGATTTGCTGCTGGTCGGGGGCAGCGCTTCGAATCTGATCCTTGCCCACCGCCTGTTGGA
TCTGGCCGGCAAAAGCGGCCTGCCCCTCACCATCGCCCTGGTCGAAAAAAGCGCCCAGTTCGGCGCCCACATCGTCAGCG
GTGCGCTCACCAAGACCCACGTCCTCGAAAAAGTCTTCCCCGACTTCAAGACAAACGGCTTTCCAATCGAGGGCTATGTC
ACCCATAGCCACCTGAGCGTGCTGGGCTCCGAGGAGCGCTGGGATCTGCCCCACGCCATCGTACCCAAAGGTTTTCGCAA
AGAGGGCCACGCCATCTTGACCCTGAGCCATGCCATCCGCTGGCTGGCGGAGCAACTGCAGGCCAAAGCCAAAGAGCTTC
CGAACGTTCTGCTGGACGTCTTTCCGGGGTTCGCCGCCCAGGAGATCCTCTACGAGGACCAGCGGGTCGCGGGTGTGCGG
GTGAGCGCCTCGGGCGACGTGTTCGAGGATGCCATCTTCGCCGAATTCACCTGCTTCGGCGACAAGGGATTCCTCTCCAA
AGACTTGGTGGAGCGTTTCGCCTTGCGCCCCAATCCCCAATTGTGGTCGGTGGGAATCAAAGAAGTCTGGGAAGTCGACC
TCGACTGTCGGGGCGTCGTCTGGCACACCCTGGGCTATCCGATTCTGGACGGCACCTTCAGCGGCGGTTTCGTCTACGGC
CTGGGCCACAAGAAACTGGCCATCGGCCTGGTGATCAGCCTGGACAGCAAAAACCCCAACCTCAACCCGCAATTGCGCCT
GCAACAGTTCAAGGCCCATCCCTGGATACAGGAACTGATCCAAGGCGGGCGGCTGCTCAAGTACGGCGCCGCGGTGATCC
CCGAGGGGGGCTACTACAGCCTGCCCACCCGCTTTGGCGTCGAAGGGGCGTTGCTGTTGGGCGATGCGTTGGGTGTCCTC
GATGCGGCCAGTCTTTCCGGTCTCGACAAATCGATGGAGACCGGTTACGTCGCCGCCGAACTGTTGCACGGCGCGTTTGT
CGACCGCAACTTCGAAGGTCTGACCGAACGCTACAAAAGTGCCGTCATGGACGGTTTCATCGGTCAGGAACTTTACGCGA
GCCGCCACTTCCGCCGGGCTTTTCTCGAAAACGACCGGCTTTTGGGCGAGTACCTGCCCGCCGTCTGCCAGAGCGTCGAT
CAGGGCCACCCCTGGCTGGGCAGTCTCAAATTCGGTCTCGGTAAACCGATCCAGCGCTCCACCGATACGTTCCAGGCTTT
GGGACTGATCCTGGGGCGCATCAGCGGCGACAAGATCTTCCGCTACACCCCTTGCCACGAGAATATCGAACCGGCCTTCA
CCCAGCCTGCTGTGGCGGTCAGCACCCAGGCGCGGCCCGAGACGCTCTTGAGCCGTCCCGACGCGGTCTTCTTTGCGGCC
CCTCGCTACCACGAGGGCAACCGCCACATCGAAGAATTCGATGCCGATACCTGCCGCCGCTGCATCGCCGTTTACGACCG
GCTGGGCAAACCCACCCCCTGCATCGCCGACTGCACCGCCGAGGTGCACCGCATCGACGAAGCGGGCGGTGTGCGTGTCC
ACGGTATGTCCCTCGAAAACTGCATCCAGTGCCGCACCTGCGAGATTGTCTGTCCGTCGGTGAATTTGCGGGTCAACCCG
ACCTACGAAGGCTCCGGCCCGGATTTCTACGGCCTGTAG

Upstream 100 bases:

>100_bases
AAATTTGCCCACCACGGCATCGTGGGCGATCTCCACCAGGTCATCCCGGAACTCATCCGCCAACTCAAACTCCAGAAGAC
CTCTACCCCGGACACGAGCC

Downstream 100 bases:

>100_bases
CATAGATCGCCGGGCTTTAAGGTTGCTGTTCTTCTTCGCCGAACAGCCTGCGCAGGATGTGCCCCTGGGCACGGTAGAGA
TCCTCGATGCGCTCCTGGTG

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSPPIRYDLLLVGGSASNLILAHRLLDLAGKSGLPLTIALVEKSAQFGAHIVSGALTKTHVLEKVFPDFKTNGFPIEGYV
THSHLSVLGSEERWDLPHAIVPKGFRKEGHAILTLSHAIRWLAEQLQAKAKELPNVLLDVFPGFAAQEILYEDQRVAGVR
VSASGDVFEDAIFAEFTCFGDKGFLSKDLVERFALRPNPQLWSVGIKEVWEVDLDCRGVVWHTLGYPILDGTFSGGFVYG
LGHKKLAIGLVISLDSKNPNLNPQLRLQQFKAHPWIQELIQGGRLLKYGAAVIPEGGYYSLPTRFGVEGALLLGDALGVL
DAASLSGLDKSMETGYVAAELLHGAFVDRNFEGLTERYKSAVMDGFIGQELYASRHFRRAFLENDRLLGEYLPAVCQSVD
QGHPWLGSLKFGLGKPIQRSTDTFQALGLILGRISGDKIFRYTPCHENIEPAFTQPAVAVSTQARPETLLSRPDAVFFAA
PRYHEGNRHIEEFDADTCRRCIAVYDRLGKPTPCIADCTAEVHRIDEAGGVRVHGMSLENCIQCRTCEIVCPSVNLRVNP
TYEGSGPDFYGL

Sequences:

>Translated_572_residues
MSPPIRYDLLLVGGSASNLILAHRLLDLAGKSGLPLTIALVEKSAQFGAHIVSGALTKTHVLEKVFPDFKTNGFPIEGYV
THSHLSVLGSEERWDLPHAIVPKGFRKEGHAILTLSHAIRWLAEQLQAKAKELPNVLLDVFPGFAAQEILYEDQRVAGVR
VSASGDVFEDAIFAEFTCFGDKGFLSKDLVERFALRPNPQLWSVGIKEVWEVDLDCRGVVWHTLGYPILDGTFSGGFVYG
LGHKKLAIGLVISLDSKNPNLNPQLRLQQFKAHPWIQELIQGGRLLKYGAAVIPEGGYYSLPTRFGVEGALLLGDALGVL
DAASLSGLDKSMETGYVAAELLHGAFVDRNFEGLTERYKSAVMDGFIGQELYASRHFRRAFLENDRLLGEYLPAVCQSVD
QGHPWLGSLKFGLGKPIQRSTDTFQALGLILGRISGDKIFRYTPCHENIEPAFTQPAVAVSTQARPETLLSRPDAVFFAA
PRYHEGNRHIEEFDADTCRRCIAVYDRLGKPTPCIADCTAEVHRIDEAGGVRVHGMSLENCIQCRTCEIVCPSVNLRVNP
TYEGSGPDFYGL
>Mature_571_residues
SPPIRYDLLLVGGSASNLILAHRLLDLAGKSGLPLTIALVEKSAQFGAHIVSGALTKTHVLEKVFPDFKTNGFPIEGYVT
HSHLSVLGSEERWDLPHAIVPKGFRKEGHAILTLSHAIRWLAEQLQAKAKELPNVLLDVFPGFAAQEILYEDQRVAGVRV
SASGDVFEDAIFAEFTCFGDKGFLSKDLVERFALRPNPQLWSVGIKEVWEVDLDCRGVVWHTLGYPILDGTFSGGFVYGL
GHKKLAIGLVISLDSKNPNLNPQLRLQQFKAHPWIQELIQGGRLLKYGAAVIPEGGYYSLPTRFGVEGALLLGDALGVLD
AASLSGLDKSMETGYVAAELLHGAFVDRNFEGLTERYKSAVMDGFIGQELYASRHFRRAFLENDRLLGEYLPAVCQSVDQ
GHPWLGSLKFGLGKPIQRSTDTFQALGLILGRISGDKIFRYTPCHENIEPAFTQPAVAVSTQARPETLLSRPDAVFFAAP
RYHEGNRHIEEFDADTCRRCIAVYDRLGKPTPCIADCTAEVHRIDEAGGVRVHGMSLENCIQCRTCEIVCPSVNLRVNPT
YEGSGPDFYGL

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=596, Percent_Identity=28.5234899328859, Blast_Score=213, Evalue=4e-55,
Organism=Escherichia coli, GI1787991, Length=408, Percent_Identity=27.6960784313726, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082155, Length=355, Percent_Identity=27.6056338028169, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786227, Length=339, Percent_Identity=28.3185840707965, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144720, Length=397, Percent_Identity=33.2493702770781, Blast_Score=204, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6324932, Length=613, Percent_Identity=28.0587275693312, Blast_Score=173, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24652256, Length=600, Percent_Identity=28.3333333333333, Blast_Score=204, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 62899; Mature: 62767

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPIRYDLLLVGGSASNLILAHRLLDLAGKSGLPLTIALVEKSAQFGAHIVSGALTKTH
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VLEKVFPDFKTNGFPIEGYVTHSHLSVLGSEERWDLPHAIVPKGFRKEGHAILTLSHAIR
HHHHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHHH
WLAEQLQAKAKELPNVLLDVFPGFAAQEILYEDQRVAGVRVSASGDVFEDAIFAEFTCFG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHEEEEEC
DKGFLSKDLVERFALRPNPQLWSVGIKEVWEVDLDCRGVVWHTLGYPILDGTFSGGFVYG
CCCCCHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCEEEHHHCCCCEECCCCCCCEEEE
LGHKKLAIGLVISLDSKNPNLNPQLRLQQFKAHPWIQELIQGGRLLKYGAAVIPEGGYYS
CCCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEECCCEECCCCCEEE
LPTRFGVEGALLLGDALGVLDAASLSGLDKSMETGYVAAELLHGAFVDRNFEGLTERYKS
CCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVMDGFIGQELYASRHFRRAFLENDRLLGEYLPAVCQSVDQGHPWLGSLKFGLGKPIQRS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC
TDTFQALGLILGRISGDKIFRYTPCHENIEPAFTQPAVAVSTQARPETLLSRPDAVFFAA
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCEEEEEC
PRYHEGNRHIEEFDADTCRRCIAVYDRLGKPTPCIADCTAEVHRIDEAGGVRVHGMSLEN
CCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHH
CIQCRTCEIVCPSVNLRVNPTYEGSGPDFYGL
HHCCCEEEEECCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SPPIRYDLLLVGGSASNLILAHRLLDLAGKSGLPLTIALVEKSAQFGAHIVSGALTKTH
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VLEKVFPDFKTNGFPIEGYVTHSHLSVLGSEERWDLPHAIVPKGFRKEGHAILTLSHAIR
HHHHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHHH
WLAEQLQAKAKELPNVLLDVFPGFAAQEILYEDQRVAGVRVSASGDVFEDAIFAEFTCFG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHEEEEEC
DKGFLSKDLVERFALRPNPQLWSVGIKEVWEVDLDCRGVVWHTLGYPILDGTFSGGFVYG
CCCCCHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCEEEHHHCCCCEECCCCCCCEEEE
LGHKKLAIGLVISLDSKNPNLNPQLRLQQFKAHPWIQELIQGGRLLKYGAAVIPEGGYYS
CCCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEECCCEECCCCCEEE
LPTRFGVEGALLLGDALGVLDAASLSGLDKSMETGYVAAELLHGAFVDRNFEGLTERYKS
CCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVMDGFIGQELYASRHFRRAFLENDRLLGEYLPAVCQSVDQGHPWLGSLKFGLGKPIQRS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC
TDTFQALGLILGRISGDKIFRYTPCHENIEPAFTQPAVAVSTQARPETLLSRPDAVFFAA
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCEEEEEC
PRYHEGNRHIEEFDADTCRRCIAVYDRLGKPTPCIADCTAEVHRIDEAGGVRVHGMSLEN
CCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHH
CIQCRTCEIVCPSVNLRVNPTYEGSGPDFYGL
HHCCCEEEEECCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]