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The map label for this gene is glpX [C]

Identifier: 37522911

GI number: 37522911

Start: 3547620

End: 3548660

Strand: Direct

Name: glpX [C]

Synonym: gvip460

Alternate gene names: 37522911

Gene position: 3547620-3548660 (Clockwise)

Preceding gene: 37522909

Following gene: 37522915

Centisome position: 76.15

GC content: 61.48

Gene sequence:

>1041_bases
ATGGAAAAAACCCTTGGCTTGGAAATTATCGAGGTAGTCGAGCAGGCCGCGATCGCGTCGGCCCGCTTGATGGGCAAAGG
ACTCAGAAACGAGGCGGACGGTGTCGCGGTCAAGGCGATGCGCGACCGCATGAACCAAATCTATATGCGCGGGCGGATCG
TGATTGGCGAAGGCGAGCGCGACGACGCCCCGATGCTCTATATCGGCGAGCAGGTGGGTATCTGCACCCAGCCCAACGCC
GCCCAGATGTGCAGTATCGACGAACTGCTCGAAATCGACATCGCCGTGGATCCCTGCGAGGGCACCAACCTGGTGGCCGA
GGGCCGGCAGGGTTCGATGGCGGTACTGGCCATCTCCGAAAAAGGCGGTCTGTTGGGGGCACCTGACCTGTACATGAAAA
AGCTTGCCGCTCCGCCCCAGGCCAAAGGCAAGGTCCATATCGACTACCCGGCCACCAAGAATTTGCAGATCATCGCCGAG
TGCCTCGATCGCGCTATCGAAGATTTGGTGGTGATCGTCATGAAGCGCGACCGCCACAAAGACTTGATTAGCGAGATCCG
CTCGACGGGGGCGCGGGTGCGCTTCATCGACGACGGCGATATTTCGGCGGCCCTTTCGGCGGGCATCAACGGCACCGGCG
TGCACGCGCTGATGGGCATCGGCGCGGCCCCCGAAGGGGTAATTTCCGCCGCTGCCCTGCGCTGTTTAGGATCGCACTTT
CAGGGCCAGCTCATCTACGATCCCGATGTGGTCCAGACCGGCCTGCTCAAGGGCACCAAAGCCGAAATCGAAGAGCAGCT
CAAAGCCCAGGGCGTCGAGCAGCCCGACAAAGTCTGGGAGGCCGAAGAACTCGCTTCCGGCAAGAATGTGCTCTTTGCCG
CCTGCGGGATCACCGACGGCGATTTTATCAAGGGCGTGCGCTTTTTCACCGGTTCCGCCCGCACCGAGACGATGGTCATC
TCCAGCCAATCCAACACCGTCCGCTTCGTGGACACCGTCCACATCCTCGACCCGGCCCACCATGCCTCGCTGGTGATCTG
A

Upstream 100 bases:

>100_bases
GGATTTGCCAGGAGCCTCGGAGGCTTCCGGCAATCCCTTTCAAGGCGTCCGGGGCGTTCTGGTACACTGAGGACCGCGGA
TGTAGATGAGGTGCGCGGCC

Downstream 100 bases:

>100_bases
CGTCTATTGCTGCAATAAGCGCAGGAAGCACGGTCCAGGCGGCTGTGCCCTTTTGTTTTGTAGAGTTTGCTTGTCTGGAC
ATTTGGTTAAAGACTATCCG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2/SBPase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MEKTLGLEIIEVVEQAAIASARLMGKGLRNEADGVAVKAMRDRMNQIYMRGRIVIGEGERDDAPMLYIGEQVGICTQPNA
AQMCSIDELLEIDIAVDPCEGTNLVAEGRQGSMAVLAISEKGGLLGAPDLYMKKLAAPPQAKGKVHIDYPATKNLQIIAE
CLDRAIEDLVVIVMKRDRHKDLISEIRSTGARVRFIDDGDISAALSAGINGTGVHALMGIGAAPEGVISAAALRCLGSHF
QGQLIYDPDVVQTGLLKGTKAEIEEQLKAQGVEQPDKVWEAEELASGKNVLFAACGITDGDFIKGVRFFTGSARTETMVI
SSQSNTVRFVDTVHILDPAHHASLVI

Sequences:

>Translated_346_residues
MEKTLGLEIIEVVEQAAIASARLMGKGLRNEADGVAVKAMRDRMNQIYMRGRIVIGEGERDDAPMLYIGEQVGICTQPNA
AQMCSIDELLEIDIAVDPCEGTNLVAEGRQGSMAVLAISEKGGLLGAPDLYMKKLAAPPQAKGKVHIDYPATKNLQIIAE
CLDRAIEDLVVIVMKRDRHKDLISEIRSTGARVRFIDDGDISAALSAGINGTGVHALMGIGAAPEGVISAAALRCLGSHF
QGQLIYDPDVVQTGLLKGTKAEIEEQLKAQGVEQPDKVWEAEELASGKNVLFAACGITDGDFIKGVRFFTGSARTETMVI
SSQSNTVRFVDTVHILDPAHHASLVI
>Mature_346_residues
MEKTLGLEIIEVVEQAAIASARLMGKGLRNEADGVAVKAMRDRMNQIYMRGRIVIGEGERDDAPMLYIGEQVGICTQPNA
AQMCSIDELLEIDIAVDPCEGTNLVAEGRQGSMAVLAISEKGGLLGAPDLYMKKLAAPPQAKGKVHIDYPATKNLQIIAE
CLDRAIEDLVVIVMKRDRHKDLISEIRSTGARVRFIDDGDISAALSAGINGTGVHALMGIGAAPEGVISAAALRCLGSHF
QGQLIYDPDVVQTGLLKGTKAEIEEQLKAQGVEQPDKVWEAEELASGKNVLFAACGITDGDFIKGVRFFTGSARTETMVI
SSQSNTVRFVDTVHILDPAHHASLVI

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family

Homologues:

Organism=Escherichia coli, GI1790360, Length=344, Percent_Identity=40.9883720930233, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789298, Length=335, Percent_Identity=37.3134328358209, Blast_Score=214, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FBSB_GLOVI (Q7NG31)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926288.1
- HSSP:   P0A9C9
- ProteinModelPortal:   Q7NG31
- SMR:   Q7NG31
- GeneID:   2601745
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3342
- HOGENOM:   HBG284837
- OMA:   GTVRFIE
- ProtClustDB:   PRK09479
- BioCyc:   GVIO251221:GLR3342-MONOMER
- InterPro:   IPR004464
- PIRSF:   PIRSF004532
- TIGRFAMs:   TIGR00330

Pfam domain/function: PF03320 FBPase_glpX

EC number: =3.1.3.11; =3.1.3.37

Molecular weight: Translated: 37030; Mature: 37030

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: BINDING 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTLGLEIIEVVEQAAIASARLMGKGLRNEADGVAVKAMRDRMNQIYMRGRIVIGEGER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
DDAPMLYIGEQVGICTQPNAAQMCSIDELLEIDIAVDPCEGTNLVAEGRQGSMAVLAISE
CCCCEEEECCCCCCCCCCCHHHHCCHHHHEEEEEEECCCCCCCEEECCCCCCEEEEEEEC
KGGLLGAPDLYMKKLAAPPQAKGKVHIDYPATKNLQIIAECLDRAIEDLVVIVMKRDRHK
CCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHH
DLISEIRSTGARVRFIDDGDISAALSAGINGTGVHALMGIGAAPEGVISAAALRCLGSHF
HHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCC
QGQLIYDPDVVQTGLLKGTKAEIEEQLKAQGVEQPDKVWEAEELASGKNVLFAACGITDG
CCEEEECCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCEEEEEECCCCC
DFIKGVRFFTGSARTETMVISSQSNTVRFVDTVHILDPAHHASLVI
HHHHHHHEEECCCCCEEEEEECCCCEEEEEEEEEEECCCCCCEECC
>Mature Secondary Structure
MEKTLGLEIIEVVEQAAIASARLMGKGLRNEADGVAVKAMRDRMNQIYMRGRIVIGEGER
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
DDAPMLYIGEQVGICTQPNAAQMCSIDELLEIDIAVDPCEGTNLVAEGRQGSMAVLAISE
CCCCEEEECCCCCCCCCCCHHHHCCHHHHEEEEEEECCCCCCCEEECCCCCCEEEEEEEC
KGGLLGAPDLYMKKLAAPPQAKGKVHIDYPATKNLQIIAECLDRAIEDLVVIVMKRDRHK
CCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHH
DLISEIRSTGARVRFIDDGDISAALSAGINGTGVHALMGIGAAPEGVISAAALRCLGSHF
HHHHHHHHCCCEEEEEECCCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCC
QGQLIYDPDVVQTGLLKGTKAEIEEQLKAQGVEQPDKVWEAEELASGKNVLFAACGITDG
CCEEEECCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCHHHHCCCCCEEEEEECCCCC
DFIKGVRFFTGSARTETMVISSQSNTVRFVDTVHILDPAHHASLVI
HHHHHHHEEECCCCCEEEEEECCCCEEEEEEEEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292